Associations of THBS2 and THBS4 polymorphisms to gastric cancer in a Southeast Chinese population
Lin X, Hu D, Chen G, Shi Y, Zhang H, Wang X, Guo X, Lu L, Black D, Zheng XW, Luo X. Associations of THBS2 and THBS4 polymorphisms to gastric cancer in a Southeast Chinese population. Cancer Genetics 2016, 209: 215-222. PMID: 27160021, DOI: 10.1016/j.cancergen.2016.04.003.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCase-Control StudiesChinaGenetic Predisposition to DiseaseGenotypeHumansMicePolymorphism, GeneticPrognosisReal-Time Polymerase Chain ReactionRNA, MessengerSpectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationStomach NeoplasmsThrombospondinsConceptsGastric cancerSoutheast Chinese populationThrombospondin-2Thrombospondin-4MRNA expressionChinese populationHuman GC tumorsMouse stomach tissuesDiffuse-type gastric cancerCase-control setsClinicopathological featuresTumor sizePoor prognosisReal-time PCRGC tumorsUnfavorable genotypesPrognosis predictionGC casesMouse stomachModest associationStomach tissueCancer developmentGC riskMRNA overexpressionHuman stomach