Xingguang Luo, MD
Associate Research Scientist in PsychiatryCards
Appointments
Psychiatry
Primary
Additional Titles
Assistant Professor, Psychiatry
Contact Info
Appointments
Psychiatry
Primary
Additional Titles
Assistant Professor, Psychiatry
Contact Info
Appointments
Psychiatry
Primary
Additional Titles
Assistant Professor, Psychiatry
Contact Info
About
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Titles
Associate Research Scientist in Psychiatry
Assistant Professor, Psychiatry
Appointments
Psychiatry
Associate Research ScientistPrimary
Other Departments & Organizations
- Division of Human Genetics
- Psychiatry
- Yale Global Mental Health Program
Education & Training
- Assistant Professor
- Yale University School of Medicine (2012)
- Post-doc (2000-2003)
- Yale University (2003)
- MD
- Shanghai Medical University (2000)
Research
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Overview
NIH R01: Fine-mapping the risk loci for alcoholism in ADH gene cluster and ALDH2 gene
NIH R21: Deep sequencing of glutamatergic pathway genes in alcohol and nicotine co-dependence
NIH R21: Post-GWAS transcriptome-wide LncRNA profiling in alcoholism
Medical Research Interests
Behavior and Behavior Mechanisms; Mental Disorders; Psychiatry and Psychology
Public Health Interests
Genetics, Genomics, Epigenetics; Mental Health; Substance Use, Addiction
ORCID
0000-0002-0909-9372
Research at a Glance
Yale Co-Authors
Frequent collaborators of Xingguang Luo's published research.
Publications Timeline
A big-picture view of Xingguang Luo's research output by year.
Research Interests
Research topics Xingguang Luo is interested in exploring.
Chiang-Shan Ray Li, MD, PhD
Joel Gelernter, MD
Ke Wang
John Krystal, MD
Jaime Ide, PhD
Heping Zhang, PhD
296Publications
10,094Citations
Mental Disorders
Publications
2026
Enhanced detection of bladder cancer using combined circulating tumor cells, urine-derived epithelial cells, and molecular biomarkers
Jiang Z, Yuan C, Yuan H, Qin C, Li Y, Hu Y, Sun C, Deng J, Deng F, Li C, Li X, Zheng J, Luo X, Pan X, Yan K, Deng G. Enhanced detection of bladder cancer using combined circulating tumor cells, urine-derived epithelial cells, and molecular biomarkers. Journal Of Cancer Research And Clinical Oncology 2026 PMID: 42107019, DOI: 10.1007/s00432-026-06469-x.Peer-Reviewed Original ResearchOmics insights into MYBL2-promoted cancer stem-like cells driving ferroptosis resistance in hepatocellular carcinoma
Chen Y, Li X, Luo C, Lin G, Zhou X, Wen Z, Su H, Meng W, Chen C, Lu J, Luo X, Jiang D, Liu H, Ning Z, Chen Y, Tam P, Pan X. Omics insights into MYBL2-promoted cancer stem-like cells driving ferroptosis resistance in hepatocellular carcinoma. Journal Of Advanced Research 2026 PMID: 41864611, DOI: 10.1016/j.jare.2026.03.039.Peer-Reviewed Original ResearchEarly Clinical Symptom Patterns Predict the Subsequent Treatment Response of Patients with Acute Schizophrenia
Liu Z, Chen W, Wang X, Huang J, Gou M, Han H, Wang J, Wang D, Chen S, Xie T, Tian L, Luo X, Li C, Li Y, Tan Y. Early Clinical Symptom Patterns Predict the Subsequent Treatment Response of Patients with Acute Schizophrenia. Schizophrenia Bulletin 2026, 52: sbag009. PMID: 41863369, PMCID: PMC13005118, DOI: 10.1093/schbul/sbag009.Peer-Reviewed Original ResearchCitationsModifications on histone tails in psychiatric disorders.
Mao Q, Luo Z, Yu Z, Chen B, Wang K, Cao Y, Ji J, Wang F, Zuo L, Li C, Wang X, Zhang Y, Luo X. Modifications on histone tails in psychiatric disorders. EC Psychology And Psychiatry 2026, 15 PMID: 42079388, PMCID: PMC13134692.Peer-Reviewed Original ResearchPhenome-wide association study of P2RX7 identifies schizophrenia and mood disorders as primary associated phenotypes
Zhu L, Mao Q, Luo Z, Chen B, Zhang Y, Lu X, Liu P, Ji J, Wang X, Wang K, Pan X, Cao Y, Liu N, Zheng J, Wang F, Yang K, Yang F, Yu Z, Hu J, Luo J, Zuo L, Wang Z, Luo X, Guo X. Phenome-wide association study of P2RX7 identifies schizophrenia and mood disorders as primary associated phenotypes. Journal Of Affective Disorders 2026, 402: 121327. PMID: 41672153, DOI: 10.1016/j.jad.2026.121327.Peer-Reviewed Original ResearchAltmetricDecreased N-acetylaspartate plus N-acetyl-aspartyl-glutamate levels in the caudate of schizophrenia patients with tardive dyskinesia
Yu T, Li Y, Li N, Gou M, Chen W, Wang Z, Tan S, Yang F, Tian B, Luo X, Tan Y. Decreased N-acetylaspartate plus N-acetyl-aspartyl-glutamate levels in the caudate of schizophrenia patients with tardive dyskinesia. Scientific Reports 2026, 16: 6773. PMID: 41617886, PMCID: PMC12913869, DOI: 10.1038/s41598-026-37396-z.Peer-Reviewed Original ResearchCitationsThe moderation effect of remnant cholesterol for linking cerebrospinal fluid interleukin 10 to blood pressure
Yang X, Su L, Fan J, Chen Y, Yang Z, Kang Y, Luo X, Han X, Liu Y, Wang F. The moderation effect of remnant cholesterol for linking cerebrospinal fluid interleukin 10 to blood pressure. Science Progress 2026, 109: 00368504251410792. PMID: 41481098, PMCID: PMC12759153, DOI: 10.1177/00368504251410792.Peer-Reviewed Original Research
2025
Concurrent TB and HIV therapies control TB reactivation during co-infection but not chronic immune activation
Sharan R, Zou Y, Singh B, Shivanna V, Dick E, Hall-Ursone S, Luo X, Guo G, Khader S, Alvarez X, Rengarajan J, Lai Z, Mehra S, Wu H, Kaushal D. Concurrent TB and HIV therapies control TB reactivation during co-infection but not chronic immune activation. Nature Communications 2025, 17: 499. PMID: 41387448, PMCID: PMC12804781, DOI: 10.1038/s41467-025-67188-4.Peer-Reviewed Original ResearchCitationsAltmetricProfiling Cell-state Fingerprints Based on Deep Learning Model with Meta-programs of Pan-cancer
Wen Z, Zhang Y, Lin G, Li X, Xiao C, Xu S, Wang J, Cao S, Chen Y, Liu H, Luo X, Chen Y, Tam P, Pan X. Profiling Cell-state Fingerprints Based on Deep Learning Model with Meta-programs of Pan-cancer. Genomics Proteomics & Bioinformatics 2025, qzaf123. PMID: 41329499, DOI: 10.1093/gpbjnl/qzaf123.Peer-Reviewed Original ResearchIDEDNIK syndrome: a newly recognized rare genetic disorder caused by AP1S1 and AP1B1 mutations
Wu R, Luo X, Wang X. IDEDNIK syndrome: a newly recognized rare genetic disorder caused by AP1S1 and AP1B1 mutations. Frontiers In Neurology 2025, 16: 1695128. PMID: 41404470, PMCID: PMC12702699, DOI: 10.3389/fneur.2025.1695128.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsCitationsAltmetric
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