2020
Abnormal functional connectivity of motor circuit in the schizophrenic patients with tardive dyskinesia: A resting-state fMRI study
Yu T, Li Y, Li N, Huang J, Fan F, Luo X, Tan S, Yang F, Tian B, Tian L, Hong L, Tan Y. Abnormal functional connectivity of motor circuit in the schizophrenic patients with tardive dyskinesia: A resting-state fMRI study. Neuroscience Letters 2020, 742: 135548. PMID: 33279570, DOI: 10.1016/j.neulet.2020.135548.Peer-Reviewed Original ResearchConceptsAbnormal Involuntary Movement ScaleTardive dyskinesiaRight postcentral gyrusInferior frontal gyrusPostcentral gyrusSchizophrenic patientsWhole brain resting-state functional connectivity (rsFC) analysisMotor circuitsLeft primary motor cortexRight supplementary motor areaFunctional connectivityPathogenesis of TDResting-state fMRI studyResting-state functional connectivity analysisFrontal gyrusAIMS total scoreLeft triangular partPrimary motor cortexAbnormal functional connectivityRight superior parietal lobuleSupplementary motor areaNegative Syndrome ScaleNon-TD groupSuperior parietal lobuleBilateral parietal cortex
2018
Resting-state Brain Activity Changes Associated with Tardive Dyskinesia in Patients with Schizophrenia: Fractional Amplitude of Low-frequency Fluctuation Decreased in the Occipital Lobe
Zhang P, Li Y, Fan F, Li CR, Luo X, Yang F, Yao Y, Tan Y. Resting-state Brain Activity Changes Associated with Tardive Dyskinesia in Patients with Schizophrenia: Fractional Amplitude of Low-frequency Fluctuation Decreased in the Occipital Lobe. Neuroscience 2018, 385: 237-245. PMID: 29909076, DOI: 10.1016/j.neuroscience.2018.06.014.Peer-Reviewed Original ResearchConceptsAbnormal Involuntary Movement ScaleMiddle occipital gyrusRight calcarine sulcusTardive dyskinesiaBrain activity changesClinical parametersLeft middle occipital gyrusSchizophrenic patientsCalcarine sulcusOccipital lobeSeverity of TDAIMS total scoreDecreased brain activityFractional amplitudeResting-state functional magnetic resonance imaging (fMRI) dataResting-state brain activityLow-frequency fluctuationsNegative Syndrome ScaleBrain activityActivity changesConstructional scoresTD groupTD patientsHealthy controlsMagnetic resonance imaging data
2013
Association of the dopamine β‐hydroxylase 19 bp insertion/deletion polymorphism with positive symptoms but not tardive dyskinesia in schizophrenia
Zhou N, Yu Q, Li X, Yu Y, Kou C, Li W, Xu H, Luo X, Zuo L, Kosten TR, Zhang XY. Association of the dopamine β‐hydroxylase 19 bp insertion/deletion polymorphism with positive symptoms but not tardive dyskinesia in schizophrenia. Human Psychopharmacology Clinical And Experimental 2013, 28: 230-237. PMID: 23559427, DOI: 10.1002/hup.2311.Peer-Reviewed Original ResearchConceptsAbnormal Involuntary Movement ScaleTardive dyskinesiaPositive symptomsDel polymorphismSeverity of TDAIMS total scoreDel/del genotypeBp insertion/deletion polymorphismIns/ins genotypeNegative Syndrome ScaleSignificant differencesInsertion/deletion polymorphismConversion of dopamineIns/delSymptom subscoresChinese patientsTD patientsDopaminergic neurotransmissionHealthy controlsMovement ScaleDBH activityPatientsSyndrome ScaleDel genotypeTD severity