2018
Stillbirth, Inflammatory Markers, and Obesity: Results from the Stillbirth Collaborative Research Network
Harrison MS, Thorsten VR, Dudley DJ, Parker CB, Koch MA, Hogue CJR, Stoll BJ, Silver RM, Varner MW, Pinar MH, Coustan DR, Saade GR, Bukowski RK, Conway DL, Willinger M, Reddy UM, Goldenberg RL. Stillbirth, Inflammatory Markers, and Obesity: Results from the Stillbirth Collaborative Research Network. American Journal Of Perinatology 2018, 35: 1071-1078. PMID: 29609190, PMCID: PMC6436964, DOI: 10.1055/s-0038-1639340.Peer-Reviewed Original ResearchConceptsWhite blood cell countElevated white blood cell countBody mass indexBlood cell countSerum ferritin levelsC-reactive protein levelsNormal body mass indexMaternal serum ferritinInflammatory markersNormal-weight womenHistologic chorioamnionitisC-reactive proteinSerum ferritinLive birthsFerritin levelsCell countLogistic regression modelsWeight womenBMI categoriesCategories of BMIMaternal serum ferritin levelsStillbirth Collaborative Research NetworkPrepregnancy body mass indexElevated body mass indexLogistic regression
2015
A Genome‐Wide Association Study of Early Spontaneous Preterm Delivery
Zhang H, Baldwin DA, Bukowski RK, Parry S, Xu Y, Song C, Andrews WW, Saade GR, Esplin MS, Sadovsky Y, Reddy UM, Ilekis J, Varner M, Biggio JR, Research F. A Genome‐Wide Association Study of Early Spontaneous Preterm Delivery. Genetic Epidemiology 2015, 39: 217-226. PMID: 25599974, PMCID: PMC4366311, DOI: 10.1002/gepi.21887.Peer-Reviewed Original ResearchConceptsSpontaneous preterm birthMaternal single nucleotide polymorphismsSPTB casesPreterm birthValidation cohortSingle nucleotide polymorphismsEarly spontaneous preterm deliveryP-valueTerm controlsTerm delivery controlsSpontaneous preterm deliveryMother-infant pairsCase-control studyIndependent validation cohortRace/ethnicityPreterm deliveryInfant morbidityMaternal ageControl groupMultiple testing adjustmentMultiple comparisonsCohortBirthNucleotide polymorphismsGenome-wide association studies
2014
Maternal serum serpin B7 is associated with early spontaneous preterm birth
Parry S, Zhang H, Biggio J, Bukowski R, Varner M, Xu Y, Andrews WW, Saade GR, Esplin MS, Leite R, Ilekis J, Reddy UM, Sadovsky Y, Blair IA, Research E. Maternal serum serpin B7 is associated with early spontaneous preterm birth. American Journal Of Obstetrics And Gynecology 2014, 211: 678.e1-678.e12. PMID: 24954659, PMCID: PMC4254341, DOI: 10.1016/j.ajog.2014.06.035.Peer-Reviewed Original ResearchConceptsSpontaneous preterm birthEarly spontaneous preterm birthPreterm birthMaternal serumSerum samplesPrevious spontaneous preterm birthSubsequent preterm deliveryProtein expressionLower gestational ageGestational age windowsCase-control studyCandidate protein expressionSerum proteomic analysisIndividual serum samplesPooled serum samplesSpontaneous pretermPreterm deliveryWeeks' gestationGestational ageTerm deliveryPregnant womenSerum biomarkersSerum concentrationsFetal membranesClinical sites