Uma Reddy, MD, MPH
Professor Adjunct of Obstetrics, Gynecology & Reproductive SciencesAbout
Titles
Professor Adjunct of Obstetrics, Gynecology & Reproductive Sciences
Biography
Dr. Reddy graduated from Brown University Magna cum laude and received her M.D. degree from the Warren Alpert Medical School of Brown University. Dr. Reddy also earned a Masters in Public Health (M.P.H.) from the Johns Hopkins Bloomberg School of Public Health. She completed her residency in Obstetrics and Gynecology at the Johns Hopkins Hospital and remained there as a Robert Wood Johnson Clinical Scholar. She completed her Maternal-Fetal Medicine fellowship at Thomas Jefferson University. She was a faculty member at the University of Maryland School of Medicine prior to joining the National Institutes of Health (NIH) as a Medical Officer in the Pregnancy and Perinatology Branch of the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD). During her tenure at NIH, she provided MFM clinical services at Walter Reed Medical Center (Bethesda, MD) and then Medstar Washington Hospital Center (Washington, DC) as a Professor of Obstetrics and Gynecology at the Georgetown University School of Medicine prior to joining Yale in 2018.
While at NIH, she oversaw many of the largest and most influential studies in obstetrics, including directing the Maternal-Fetal Medicine Units (MFMU) Network which funds multiple clinical trials across the country. Her research on stillbirth as part of the Stillbirth Collaborative Research Network (SCRN), preterm birth and labor management has had a profound impact on obstetrical practice both in the United States and internationally. She received numerous NIH awards for her role in advancing women’s health research agenda nationally.
Dr. Reddy is widely recognized as a scholar, educator, and mentor. Dr. Reddy has been selected to serve as a Member of the American College of Obstetrics and Gynecology (ACOG) Committee on Practice Bulletins – Obstetrics; Fellow of the American Gynecological & Obstetrical Society and was selected as Fellow in Executive Leadership in Academic Medicine (ELAM) Program for Women, 2020-2021 Class. She has published 250 peer reviewed articles, many in the most impactful journals including NEJM and JAMA.
Dr. Reddy is board certified in Obstetrics and Gynecology and Maternal-Fetal Medicine. Her expertise is in the management of high-risk pregnancies complicated by prior preterm birth or pregnancy loss as well as maternal conditions such as diabetes, hypertension, and connective tissue disorders such as lupus.
Departments & Organizations
- Improving Clinical Care for Recurrent Pregnancy Loss
- Yale Center for Genomic Health
Education & Training
- Fellow
- Thomas Jefferson University (2000)
- MPH
- Johns Hopkins Bloomberg School of Public Health, Biostatistics (1999)
- Robert Wood Johnson Clinical Scholar
- Johns Hopkins University (1997)
- Resident
- Johns Hopkins Hospital (1995)
- Intern
- Johns Hopkins Hospital (1992)
- MD
- The Warren Alpert Medical School of Brown University (1991)
- ScB
- Brown University, Biology (1988)
Research
Overview
Medical Research Interests
ORCID
0000-0001-5519-1527
Research at a Glance
Yale Co-Authors
Publications Timeline
Research Interests
Heping Zhang, PhD
Katherine Harper Campbell, MD, MPH
Lena Sweeney, MD, BS
Xiao Xu, PhD, MA
Jennifer Culhane
Lisbet Lundsberg, PhD
Pregnant People
Publications
2025
Adherence to Recommended Prenatal Visit Schedules and Risk for Stillbirth, According to Probable Cause of Death
Cersonsky T, Ayala N, Tucker N, Saade G, Dudley D, Pinar H, Silver R, Reddy U, Lewkowitz A. Adherence to Recommended Prenatal Visit Schedules and Risk for Stillbirth, According to Probable Cause of Death. Obstetrical & Gynecological Survey 2025, 80: 331-333. DOI: 10.1097/ogx.0000000000001412.Peer-Reviewed Original ResearchOptimal Timing of Delivery for Pregnant Individuals With Mild Chronic Hypertension
Metz T, Kuo H, Harper L, Sibai B, Longo S, Saade G, Dugoff L, Aagaard K, Boggess K, Lawrence K, Hughes B, Bell J, Edwards R, Gibson K, Haas D, Plante L, Casey B, Esplin S, Hoffman M, Hoppe K, Foroutan J, Tuuli M, Owens M, Simhan H, Frey H, Rosen T, Palatnik A, Baker S, August P, Reddy U, Kinzler W, Su E, Krishna I, Nguyen N, Norton M, Skupski D, El-Sayed Y, Ogunyemi D, Librizzi R, Pereira L, Magann E, Habli M, Williams S, Mari G, Pridjian G, McKenna D, Parrish M, Chang E, Quiñones J, Galis Z, Ambalavanan N, Sinkey R, Szychowski J, Tita A. Optimal Timing of Delivery for Pregnant Individuals With Mild Chronic Hypertension. Obstetric Anesthesia Digest 2025, 45: 90-90. DOI: 10.1097/01.aoa.0001113116.76046.0f.Peer-Reviewed Original ResearchConceptsAmerican College of Obstetricians and GynecologistsChronic hypertensionTime of deliveryOptimal timing of deliveryAssociated with higher risk of adverse eventsObstetricians and GynecologistsWeeks of gestationMild chronic hypertensionAssociated with higher riskHigher risk of adverse eventsRisk of adverse eventsOptimal timingAnd GynecologistsPreterm birthPregnant womenAdverse eventsPregnant individualsAmerican CollegeAffected womenReduction of riskCliniciansGestationPregnancyHypertensionDeliveryHypertensive disorders of pregnancy and neuroimaging markers of dementia risk: A pilot study
Alshikho M, Haghighi N, Ravi R, Solomon V, Rangel E, Pyne J, Bista K, Chang J, Lippert R, Cotton‐Samuel D, Cedano S, De La Cruz Vasquez N, Haro C, Chiu J, Chen Y, Reddy U, McNeil B, Pemberton V, Yee L, Parrish T, Brickman A, Miller E, Investigators F. Hypertensive disorders of pregnancy and neuroimaging markers of dementia risk: A pilot study. Pregnancy 2025, 1 DOI: 10.1002/pmf2.70020.Peer-Reviewed Original ResearchCitationsConceptsHistory of HDPCerebral blood flowRegional cerebral blood flowWhite matter hyperintensityBrain MRIGray matter volumeHypertensive disordersRisk of cognitive declineAssociation of HDPSmall-for-gestational age infantsCognitive declineFractional anisotropyPilot studyHypertensive disorders of pregnancyRegional gray matter volumeWhite matter hyperintensity volumeMicrovascular brain injuryAssociated with long-term impairmentDisorders of pregnancyDementia riskMulticenter prospective cohortTrimester of pregnancyHigh-resolution brain MRIHealth StudyIndex deliveryAssociation between Induction Start Time and Labor Duration in Nulliparous Women Undergoing Elective Induction of Labor
Facco F, MacPherson C, Reddy U, Tita A, Silver R, El-Sayed Y, Wapner R, Rouse D, Saade G, Thorp J, Chauhan S, Costantine M, Chien E, Heyborne K, Srinivas S, Swamy G, Grobman W, Network F. Association between Induction Start Time and Labor Duration in Nulliparous Women Undergoing Elective Induction of Labor. American Journal Of Perinatology 2025 PMID: 40015324, DOI: 10.1055/a-2547-4196.Peer-Reviewed Original ResearchConceptsInduction of laborCesarean delivery rateLabor durationShorter labor durationElective inductionBishop scoreNulliparous womenLow-risk nulliparous womenElective induction of laborModified Bishop scoreMean labour durationMulti-center randomized controlled trialDelivery rateBaseline maternal characteristicsBody mass indexFrequency of deliveryARRIVE trialInsurance statusCervical statusMaternal characteristicsSecondary analysisRupture of membranesSpontaneous laborWeeks 0 daysWomen MethodsThe association of cytomegalovirus hyperimmune globulin with adverse pregnancy outcomes
Rouse D, MacPherson C, Saade G, Dinsmoor M, Reddy U, Pass R, Allard D, Mallett G, Clifton R, Gyamfi-Bannerman C, Varner M, Goodnight W, Tita A, Costantine M, Swamy G, Heyborne K, Chien E, Chauhan S, El-Sayed Y, Casey B, Parry S, Simhan H, Napolitano P, Macones G, Hughes B, Network E. The association of cytomegalovirus hyperimmune globulin with adverse pregnancy outcomes. American Journal Of Obstetrics And Gynecology 2025 PMID: 40221073, DOI: 10.1016/j.ajog.2025.04.014.Peer-Reviewed Original ResearchAltmetricAssociation of maternal nocturnal heart rate and adverse pregnancy outcomes
Fisher S, Huang X, Khan S, Grimaldi D, Zee P, Greenland P, Grobman W, Silver R, Facco F, Redline S, Basner R, Louis J, Pien G, Sherman‐Brown A, Schubert F, Parry S, Reddy U, Yee L, Study F. Association of maternal nocturnal heart rate and adverse pregnancy outcomes. Pregnancy 2025, 1 DOI: 10.1002/pmf2.70015.Peer-Reviewed Original ResearchConceptsSmall-for-gestational ageHypertensive disorders of pregnancyDisorders of pregnancyAdverse pregnancy outcomesNocturnal heart rateOdds of gestational diabetesGestational diabetesPregnancy outcomesAssociated with higher oddsHypertensive disordersFollow-upHeart rateHigher oddsMarkers of cardiometabolic disease riskOdds of small-for-gestational ageHome sleep studiesMultivariate logistic regression modelCardiometabolic disease riskDecreased parasympathetic activityPreterm birthLogistic regression modelsNonpregnant adultsSleep studiesProspective cohortLate pregnancyComparing Population-Based Fetal Growth Standards in a US Cohort
Gleason J, Reddy U, Chen Z, Grobman W, Wapner R, Steller J, Simhan H, Scifres C, Blue N, Parry S, Grantz K. Comparing Population-Based Fetal Growth Standards in a US Cohort. Obstetrical & Gynecological Survey 2025, 80: 141-143. DOI: 10.1097/01.ogx.0001110340.97832.86.Peer-Reviewed Original ResearchIntersectionality of individual and neighborhood‐level adverse social determinants of health in early pregnancy
Hamilton J, Grobman W, Wu J, Yee L, Haas D, Mcneil B, Mercer B, Simhan H, Reddy U, Silver R, Parry S, Saade G, Wu J, Lynch C, Venkatesh K. Intersectionality of individual and neighborhood‐level adverse social determinants of health in early pregnancy. Pregnancy 2025, 1 DOI: 10.1002/pmf2.70002.Peer-Reviewed Original ResearchAltmetricConceptsIndividual-level social determinants of healthNeighborhood-level social determinants of healthSocial determinants of healthHigher socioeconomic disadvantageInadequate food accessSDoH measuresLow walkabilitySocioeconomic disadvantageFood accessNulliparous individualsMultiple social determinants of healthNeighborhood-level social determinantsUSDA Food Access Research AtlasFood Access Research AtlasNeighborhood-level measuresAdverse social determinantsArea Deprivation IndexParticipant's home addressDeterminants of healthSecondary analysis of dataNulliparous Pregnancy Outcomes StudyMonitoring Mothers-to-BeLower household incomeCensus tract levelLower educational attainmentPrediction of Hepatitis C Virus Perinatal Transmission in Pregnant Individuals With Hepatitis C Virus Infection
Sandoval G, Saade G, Hughes B, Clifton R, Reddy U, Bartholomew A, Salazar A, Chien E, Tita A, Thorp J, Metz T, Wapner R, Sabharwal V, Simhan H, Swamy G, Heyborne K, Sibai B, Grobman W, El-Sayed Y, Casey B, Parry S, Macones G, Prasad M. Prediction of Hepatitis C Virus Perinatal Transmission in Pregnant Individuals With Hepatitis C Virus Infection. Obstetrics And Gynecology 2025, 145: 449-452. PMID: 40014859, PMCID: PMC11925659, DOI: 10.1097/aog.0000000000005872.Peer-Reviewed Original ResearchAltmetricMeSH Keywords and ConceptsConceptsHepatitis C virus infectionPerinatal transmissionHepatitis C virusHepatitis C virus perinatal transmissionPregnant individualsEunice Kennedy Shriver National Institute of Child HealthTransmission of HCV infectionPerinatal transmission rateHCV RNA titersNeonatal follow-upC virus infectionPositive HCV antibodyMulticenter observational studyArea under the curveNational Institute of Child HealthInstitute of Child HealthAntibody-positive participantsAntepartum bleedingHCV infectionHCV antibodiesFollow-upRNA titersC virusObservational studyClinical counselingPrenatal Cannabis Use and Depressive Symptoms
Pitt T, Allshouse A, Kim P, McMillin G, Silver R, Chung J, Grobman W, Haas D, Mercer B, Parry S, Reddy U, Saade G, Simhan H, Metz T. Prenatal Cannabis Use and Depressive Symptoms. Obstetrics And Gynecology 2025, 145: 417-425. PMID: 40014863, PMCID: PMC11925678, DOI: 10.1097/aog.0000000000005860.Peer-Reviewed Original ResearchAltmetricMeSH Keywords and ConceptsConceptsAssociated with later depressive symptomsCannabis exposureDepressive symptomsCannabis useTHC-COOHAssociated with increased depressive symptomsAssociated with greater oddsAssociated with depressive symptomsFirst-trimesterExposed to cannabisPregnancy outcome dataWeeks of gestationFirst-trimester exposureGreater oddsCannabis metabolitesSecondary analysisCannabisAssociated with increased oddsExploratory analysisUrine immunoassayTrimesterHigher levelsPrimary outcomePregnancyAcademic centers
Academic Achievements & Community Involvement
Honors
honor NICHD Individual Merit Award for leading the Opioid Research Effort
01/01/2017National AwardThe Eunice Kennedy Shriver National Institute for Child Health and Human DevelopmentDetailsUnited Stateshonor NICHD Merit Award for NICHD Clinical Trials Stewardship Working Group
12/01/2015National AwardThe Eunice Kennedy Shriver National Institute for Child Health and Human DevelopmentDetailsUnited Stateshonor National Institutes Office of the Director Honor Award for Team to Re-Engineer Scientific Oversight of Women and Minority Inclusion
01/01/2015National AwardNational Institutes OfficeDetailsUnited Stateshonor National Institutes of Health Director’s Group Award for Pregnancy and Perinatology Branch Stillbirth Research Team
01/01/2014National AwardNational InstitutesDetailsUnited Stateshonor National Institutes of Health Merit Award for Leadership of stillbirth research that has contributed to the successful accomplishment of the NICHD mission
01/01/2012National AwardThe Eunice Kennedy Shriver National Institute for Child Health and Human DevelopmentDetailsUnited States