2024
Adverse Pregnancy Outcomes and Predicted 30-Year Risk of Maternal Cardiovascular Disease 2–7 Years After Delivery
Venkatesh K, Khan S, Yee L, Wu J, McNeil R, Greenland P, Chung J, Levine L, Simhan H, Catov J, Scifres C, Reddy U, Pemberton V, Saade G, Merz C, Grobman W, Mothers-to-Be A. Adverse Pregnancy Outcomes and Predicted 30-Year Risk of Maternal Cardiovascular Disease 2–7 Years After Delivery. Obstetrics And Gynecology 2024, 143: 775-784. PMID: 38574364, PMCID: PMC11098696, DOI: 10.1097/aog.0000000000005569.Peer-Reviewed Original ResearchConceptsRisk of atherosclerotic CVDAtherosclerotic CVD riskAdverse pregnancy outcomesHypertensive disorders of pregnancyAtherosclerotic CVDCVD riskDisorders of pregnancyPregnancy outcomesHypertensive disordersPreterm birthModified Poisson modelsFramingham risk scoreRisk of CVDRisk of atherosclerotic cardiovascular diseaseMagnitude of riskAbsolute riskAtherosclerotic cardiovascular diseaseSecondary analysisLongitudinal cohortRisk scoreGestational ageGreater riskBaseline covariatesCardiovascular diseaseDisease 2
2023
Risk Factors for Perinatal Transmission of Hepatitis C Virus
Prasad M, Saade G, Clifton R, Sandoval G, Hughes B, Reddy U, Bartholomew A, Salazar A, Chien E, Tita A, Thorp J, Metz T, Wapner R, Sabharwal V, Simhan H, Swamy G, Heyborne K, Sibai B, Grobman W, El-Sayed Y, Casey B, Parry S, Rathore M, Diaz-Velasco R, Puga A, Wiznia A, Kovacs A, Garry D, Macones G. Risk Factors for Perinatal Transmission of Hepatitis C Virus. Obstetrics And Gynecology 2023, 142: 449-456. PMID: 37590978, PMCID: PMC10437102, DOI: 10.1097/aog.0000000000005306.Peer-Reviewed Original ResearchMeSH KeywordsChildFemaleHepacivirusHepatitis CHumansPregnancyProspective StudiesRisk FactorsRNAUterine HemorrhageConceptsPerinatal transmissionHCV infectionRisk factorsPrimary outcomeHuman Development Maternal-Fetal Medicine Units NetworkMaternal-Fetal Medicine Units NetworkHepatitis C virus infectionEunice Kennedy Shriver National InstituteC virus infectionPerinatal transmission rateWeeks of gestationHigh viral loadHepatitis C virusMonths of lifePositive test resultsAntepartum bleedingViremic participantsVaginal bleedingHCV RNAViremic individualsViral loadC virusObservational studyVirus infectionDemonstrable viremiaSearching and visualizing genetic associations of pregnancy traits by using GnuMoM2b
Yan Q, Guerrero R, Khan R, Surujnarine A, Wapner R, Hahn M, Raja A, Salleb-Aouissi A, Grobman W, Simhan H, Blue N, Silver R, Chung J, Reddy U, Radivojac P, Pe’er I, Haas D. Searching and visualizing genetic associations of pregnancy traits by using GnuMoM2b. Genetics 2023, 225: iyad151. PMID: 37602697, PMCID: PMC10691790, DOI: 10.1093/genetics/iyad151.Peer-Reviewed Original ResearchMeSH KeywordsFemaleGenome-Wide Association StudyHumansPhenomicsPhenotypePolymorphism, Single NucleotidePregnancyRisk FactorsConceptsAdverse pregnancy outcomesNulliparous Pregnancy Outcomes StudyPregnancy Outcomes StudyMajor risk factorGenome-wide association studiesPregnancy outcomesGenetic associationMonitoring MothersRisk factorsOutcome studiesWomen's healthPhenome-wide association studySingle nucleotide polymorphismsAssociation studiesGenetic resultsPregnancyNucleotide polymorphismsGroup B streptococcus colonization in pregnancy and neighborhood socioeconomic disadvantage
Bank T, Yee L, Lynch C, Wu J, Johnson J, McNeil R, Mercer B, Simhan H, Reddy U, Silver R, Parry S, Saade G, Chung J, Wapner R, Grobman W, Venkatesh K. Group B streptococcus colonization in pregnancy and neighborhood socioeconomic disadvantage. American Journal Of Obstetrics And Gynecology 2023, 229: 564-566.e7. PMID: 37487854, DOI: 10.1016/j.ajog.2023.07.028.Peer-Reviewed Original Research
2022
Association of Social Determinants of Health and Clinical Factors with Postpartum Hospital Readmissions among Nulliparous Individuals
Kumar N, Grobman W, Haas D, Silver R, Reddy U, Simhan H, Wing D, Mercer B, Yee L. Association of Social Determinants of Health and Clinical Factors with Postpartum Hospital Readmissions among Nulliparous Individuals. American Journal Of Perinatology 2022, 40: 348-355. PMID: 36427510, DOI: 10.1055/s-0042-1758485.Peer-Reviewed Original ResearchConceptsPostpartum readmissionSocial determinantsHypertensive disordersHigher oddsMulticenter prospective cohort studyPostpartum hospital readmissionProspective cohort studyInitial hospital dischargeHemorrhage requiring transfusionSuch risk factorsAntecedent diagnosisHDP patientsNulliparous participantsGestational diabetesIntrapartum complicationsPerinatal morbidityCesarean deliveryCohort studyHospital dischargeClinical factorsHospital readmissionPrimary outcomeBivariable analysisModifiable factorsInsurance status
2021
Maternal serum fructosamine levels and stillbirth: a case–control study of the Stillbirth Collaborative Research Network
Arslan E, Allshouse A, Page J, Varner M, Thorsten V, Parker C, Dudley D, Saade G, Goldenberg R, Stoll B, Hogue C, Bukowski R, Conway D, Pinar H, Reddy U, Silver R. Maternal serum fructosamine levels and stillbirth: a case–control study of the Stillbirth Collaborative Research Network. BJOG An International Journal Of Obstetrics & Gynaecology 2021, 129: 619-626. PMID: 34529344, DOI: 10.1111/1471-0528.16922.Peer-Reviewed Original ResearchConceptsSerum fructosamine levelsFructosamine levelsCase-control studyTime of deliveryLive birthsStillbirth Collaborative Research NetworkLive birth controlsCases of stillbirthPotential confounding factorsGeographic catchment areaSingleton stillbirthsGlycaemic controlDiabetes statusMulticentre studyRoutine screeningFructosamine measurementsDiabetesStillbirthConfounding factorsSecondary analysisWomenBirthCollaborative research networksBirth controlResearch NetworkChronic hypertension, perinatal mortality and the impact of preterm delivery: a population‐based study
Grover S, Brandt J, Reddy U, Ananth C. Chronic hypertension, perinatal mortality and the impact of preterm delivery: a population‐based study. BJOG An International Journal Of Obstetrics & Gynaecology 2021, 129: 572-579. PMID: 34536318, PMCID: PMC9214277, DOI: 10.1111/1471-0528.16932.Peer-Reviewed Original ResearchConceptsPerinatal mortality rateChronic hypertensionEarly term deliveryPreterm deliveryPerinatal mortalityMortality rateTerm deliverySingleton birthsCausal mediation analysisMaternal chronic hypertensionElevated blood pressureModifiable risk factorsPopulation-based studyWeeks of gestationLate-term gestationCross-sectional analysisNormotensive pregnanciesPreterm birthBlood pressureTerm gestationPerinatal deathRisk factorsHypertensionMAIN OUTCOMEMortalityMaternal outcomes and risk factors for COVID-19 severity among pregnant women
Vouga M, Favre G, Martinez-Perez O, Pomar L, Acebal LF, Abascal-Saiz A, Hernandez MRV, Hcini N, Lambert V, Carles G, Sichitiu J, Salomon L, Stirnemann J, Ville Y, de Tejada BM, Goncé A, Hawkins-Villarreal A, Castillo K, Solsona EG, Trigo L, Cleary B, Geary M, Bartels H, Al-Kharouf F, Malone F, Higgins M, Keating N, Knowles S, Poncelet C, Ribeiro-do-Valle CC, Surita F, Dantas-Silva A, Borrelli C, Luz AG, Fuenzalida J, Carvajal J, Canales MG, Hernandez O, Grechukhina O, Ko AI, Reddy U, Figueiredo R, Moucho M, Pinto PV, De Luca C, De Santis M, de Campos DA, Martins I, Garabedian C, Subtil D, Bohrer B, Da Rocha Oppermann ML, Wender MCO, Schuler-Faccini L, Sanseverino MTV, Giugliani C, Friedrich L, Scherer MH, Mottet N, Ducarme G, Pelerin H, Moreau C, Breton B, Quibel T, Rozenberg P, Giannoni E, Granado C, Monod C, Mueller D, Hoesli I, Bassler D, Heldstab S, Kölble NO, Sentilhes L, Charvet M, Deprest J, Richter J, Van der Veeken L, Eggel-Hort B, Plantefeve G, Derouich M, Calvache AJN, Lopez-Giron MC, Burgos-Luna JM, Escobar-Vidarte MF, Hecher K, Tallarek AC, Hadar E, Haratz KK, Amikam U, Malinger G, Maymon R, Yogev Y, Schäffer L, Toussaint A, Rossier MC, De Sa RAM, Grawe C, Aebi-Popp K, Radan AP, Raio L, Surbek D, Böckenhoff P, Strizek B, Kaufmann M, Bloch A, Boulvain M, Johann S, Heldstab SA, Bernasconi MT, Grant G, Feki A, Brochut AM, Giral M, Sedille L, Papadia A, Brugger RC, Weber B, Fischer T, Kahlert C, Saines KN, Cambou M, Kanellos P, Chen X, Yin M, Haessig A, Ackermann S, Baud D, Panchaud A. Maternal outcomes and risk factors for COVID-19 severity among pregnant women. Scientific Reports 2021, 11: 13898. PMID: 34230507, PMCID: PMC8260739, DOI: 10.1038/s41598-021-92357-y.Peer-Reviewed Original ResearchConceptsSevere maternal outcomesPregnant womenRisk factorsMaternal outcomesPulmonary comorbiditiesHypertensive disordersNeonatal outcomesSevere complicationsHigh riskSevere acute respiratory syndrome coronavirus 2Severe coronavirus disease-19Severe COVID-19 diseaseAcute respiratory syndrome coronavirus 2Neonatal intensive care unitSARS-CoV-2 infectionRespiratory syndrome coronavirus 2Immediate neonatal outcomeIntensive care unitSyndrome coronavirus 2COVID-19 severityCase-control studyCoronavirus disease-19SARS-CoV-2COVID-19 diseaseMaternal disease
2020
Stillbirth and fetal anomalies: secondary analysis of a case–control study
Son S, Allshouse A, Page J, Debbink M, Pinar H, Reddy U, Gibbins K, Stoll B, Parker C, Dudley D, Varner M, Silver R. Stillbirth and fetal anomalies: secondary analysis of a case–control study. BJOG An International Journal Of Obstetrics & Gynaecology 2020, 128: 252-258. PMID: 32946651, PMCID: PMC7902300, DOI: 10.1111/1471-0528.16517.Peer-Reviewed Original ResearchAn international registry for emergent pathogens and pregnancy
Panchaud A, Favre G, Pomar L, Vouga M, Aebi-Popp K, Baud D, Ann-Christin T, Brigitte S, Kurt H, Paul B, Susanne S, Edward M, Rebecca B, Clare W, Daniel R, Jan D, Jute R, Adriana G, Betania B, Carolina C, Fernanda G, Lavinia S, Celeste O, Lucia D, Augusto M, Silvana Q, Ana S, Arifa R, Audrey H, Christopher N, Fatima K, Howard B, Isabelle B, Jean-Charles P, John S, Jonathan Z, Meagan L, Wendy W, Javiera F, Jorge C, Manuel G, Olivia H, Mingzhu Y, Xiang C, Xiaolong Q, Enrique S, Ricardo G, Africa C, Agueda R, Albert T, Alberto P, Maria C, Ana C, Ana V, Cristina F, Maria F, Angeles S, Anna G, Antonio R, Antonio S, Beatriz M, Begona M, Belen G, Camino F, Carlos L, Carmen B, Maria O, Cristina A, Cristina L, Cristina R, Elena F, Elena P, Encarnacion C, Esther A, Maria C, Eva M, Maria M, Maria O, Jesus G, Iène A, Iratxe O, Irene G, de Alba Fernandez Isabel C, Javier A, Jorge D, Jose A, José N, José R, Antonio S, Manuel A, Roman B, de Alva Juan Carlos W, Laura F, Laura G, Longinos A, Lucas C, Lucas T, Lucia D, Carmen P, Magdalena M, Manuel D, Mar M, Maria C, Maria N, Maria S, Maria T, Maria Z, Begona D, Carmen G, del P, del Carmen B, del Carmen M, Isabel P, Joaquina G, José N, José P, Marta C, Marta G, Ruth M, Mercedes F, Mercedes R, Monica C, Monica C, Noelia P, Olga N, Onofre A, Oscar M, Oscar V, del B, Pilar M, Pilar P, Porfirio V, Raquel G, Raquel J, Rebeca A, Rocio L, Maria O, Rosario R, Rut B, Sandra C, Silvia M, Susana F, Susana S, Tania M, Vitor M, Albert K, Anthony J, Karin N, Mary C, Olga G, Sahara N, Uma R, Zubin S, Bénédicte B, Charles G, Charline B, Christophe P, Damien S, Didier M, Didier M, Estelle H, Gaetan P, Guillaume D, Helene P, Jerome D, Judith C, Julien S, Véronique L, Najeh H, Laurent S, Loïc S, Marylene G, Nicolas M, Olivier M, Patrick R, Sedille L, Thibaud Q, Vasiliki K, Véronique E, Yves V, Gabriel C, Ina R, Brian C, Fergal M, Mary H, Michael G, Eran H, Eran H, Gustavo M, Hen S, Karina K, Ron M, Yariv Y, Carmen D, Marco D, Telefono R, David A, Emilija B, Fernando G, Thomas V, Enrique G, Jeannette M, Walter V, Alcides P, Alcides P, de Campos Diogo A, Nadia C, Pedro V, Diomede N, Stephen R, Alice P, Anda-Petronela R, Andrea P, Andrea B, Anis F, Anne-Claude M, Arnaud T, Béatrice E, de Tejada Begoña M, Brigitte F, Brigitte W, Carolin B, Cécile M, Christian K, Cora V, Daniel S, David B, Dirk B, Doris M, Barbara P, Eva G, Friederike R, Giannoni E, Guillaume F, Irene H, Jérôme M, Karine L, Karoline A, Leo P, Leonhard S, Luigi R, Manon V, Margaret H, Marie-Claude R, Markus H, Martin K, Mathilde G, Michel B, Monya T, Myriam B, Nicole O, Omar J, Panagiotis K, Pascale B, Romina C, Sandra H, Andrea H, Sylvie R, Tina F, Ursula W, Valentine L, Wawrzyniec R, Gilbert G, Carole G, C P, Angel H, José N. An international registry for emergent pathogens and pregnancy. The Lancet 2020, 395: 1483-1484. PMID: 32353329, PMCID: PMC7185939, DOI: 10.1016/s0140-6736(20)30981-8.Peer-Reviewed Original ResearchBetacoronavirusCommunicable Diseases, EmergingCoronavirus InfectionsCOVID-19Diagnostic Screening ProgramsFemaleFetusHumansInterdisciplinary PlacementPandemicsPneumonia, ViralPregnancyPregnancy OutcomeRegistriesRisk AssessmentRisk FactorsSARS-CoV-2Severe Acute Respiratory SyndromeZika VirusZika Virus Infection
2019
Severe maternal morbidity during delivery hospitalisation in a large international administrative database, 2008–2013: a retrospective cohort
Lipkind H, Zuckerwise L, Turner E, Collins J, Campbell K, Reddy U, Illuzi J, Merriam A. Severe maternal morbidity during delivery hospitalisation in a large international administrative database, 2008–2013: a retrospective cohort. BJOG An International Journal Of Obstetrics & Gynaecology 2019, 126: 1223-1230. PMID: 31100201, DOI: 10.1111/1471-0528.15818.Peer-Reviewed Original ResearchMeSH KeywordsAdultAustraliaCenters for Disease Control and Prevention, U.S.ComorbidityDatabases, FactualEnglandFemaleHospitalizationHumansMaternal AgeMaternal DeathMiddle AgedObstetric Labor ComplicationsPregnancyPregnancy ComplicationsPregnancy OutcomeRetrospective StudiesRisk FactorsUnited StatesYoung AdultConceptsSevere maternal morbidityMaternal morbidityDelivery hospitalisationRetrospective cohortRisk factorsSevere maternal morbidity ratesMaternal morbidity ratesAcute renal failureLife-threatening diagnosisAdvanced maternal ageLife-saving procedureLarge university hospitalChi-square testMorbidity variesPregnancy complicationsClinical characteristicsIntravascular coagulationRenal failureSevere morbidityMultivariable analysisMorbidity rateAdverse outcomesClinical differencesMaternal ageUniversity Hospital
2018
Stillbirth, Inflammatory Markers, and Obesity: Results from the Stillbirth Collaborative Research Network
Harrison MS, Thorsten VR, Dudley DJ, Parker CB, Koch MA, Hogue CJR, Stoll BJ, Silver RM, Varner MW, Pinar MH, Coustan DR, Saade GR, Bukowski RK, Conway DL, Willinger M, Reddy UM, Goldenberg RL. Stillbirth, Inflammatory Markers, and Obesity: Results from the Stillbirth Collaborative Research Network. American Journal Of Perinatology 2018, 35: 1071-1078. PMID: 29609190, PMCID: PMC6436964, DOI: 10.1055/s-0038-1639340.Peer-Reviewed Original ResearchConceptsWhite blood cell countElevated white blood cell countBody mass indexBlood cell countSerum ferritin levelsC-reactive protein levelsNormal body mass indexMaternal serum ferritinInflammatory markersNormal-weight womenHistologic chorioamnionitisC-reactive proteinSerum ferritinLive birthsFerritin levelsCell countLogistic regression modelsWeight womenBMI categoriesCategories of BMIMaternal serum ferritin levelsStillbirth Collaborative Research NetworkPrepregnancy body mass indexElevated body mass indexLogistic regressionPotentially Preventable Stillbirth in a Diverse U.S. Cohort
Page JM, Thorsten V, Reddy UM, Dudley DJ, Hogue CJR, Saade GR, Pinar H, Parker CB, Conway D, Stoll BJ, Coustan D, Bukowski R, Varner MW, Goldenberg RL, Gibbins K, Silver RM. Potentially Preventable Stillbirth in a Diverse U.S. Cohort. Obstetrics And Gynecology 2018, 131: 336-343. PMID: 29324601, PMCID: PMC5785410, DOI: 10.1097/aog.0000000000002421.Peer-Reviewed Original ResearchConceptsStillbirth Collaborative Research NetworkPreventable stillbirthsPlacental insufficiencyHypertensive disordersMultiple gestationsMedical complicationsPopulation-based case-control studyDiverse U.S. cohortSpontaneous preterm birthMedical record abstractionWeeks of gestationCases of stillbirthCase-control studyCollaborative research networksResearch NetworkStillbirth reductionPreterm laborPreterm birthPlacental pathologyRecord abstractionNonanomalous fetusesMaternal interviewsPostmortem examinationU.S. cohortStillbirth
2016
Stillbirths: recall to action in high-income countries
Flenady V, Wojcieszek A, Middleton P, Ellwood D, Erwich J, Coory M, Khong T, Silver R, Smith G, Boyle F, Lawn J, Blencowe H, Leisher S, Gross M, Horey D, Farrales L, Bloomfield F, McCowan L, Brown S, Joseph K, Zeitlin J, Reinebrant H, Cacciatore J, Ravaldi C, Vannacci A, Cassidy J, Cassidy P, Farquhar C, Wallace E, Siassakos D, Heazell A, Storey C, Sadler L, Petersen S, Frøen J, Goldenberg R, Flenady V, Frøen J, Kinney M, de Bernis L, Lawn J, Blencowe H, Heazell A, Leisher S, Ruidiaz J, Carvalho A, Dahlstrom J, East C, Fox J, Gibbons K, Ibiebele I, Kildea S, Gardener G, Lourie R, Wilson P, Gordon A, Jennings B, Kent A, McDonald S, Merchant K, Oats J, Walker S, Raven L, Schirmann A, de Montigny F, Guyon G, Blondel B, de Wall S, Bonham S, Corcoran P, Cregan M, Meany S, Murphy M, Fukui S, Gordijn S, Korteweg F, Cronin R, Mason V, Culling V, Usynina A, Pettersson K, Rådestad I, van Gogh S, Bichara B, Bradley S, Ellis A, Downe S, Draper E, Manktelow B, Scott J, Smith L, Stones W, Lavender T, Duke W, Fretts R, Gold K, McClure E, Reddy U. Stillbirths: recall to action in high-income countries. The Lancet 2016, 387: 691-702. PMID: 26794070, DOI: 10.1016/s0140-6736(15)01020-x.Peer-Reviewed Original ResearchMeSH KeywordsAttitude to HealthData AccuracyDelivery of Health CareDeveloped CountriesFemaleGestational AgeGlobal HealthHealth PolicyHealthcare DisparitiesHospice CareHumansIncomeInternational CooperationPerinatal MortalityPostnatal CarePractice Guidelines as TopicPregnancyPrenatal CareRisk FactorsStereotypingStillbirthConceptsHigh-income countriesStillbirth rateLate gestation stillbirthAdverse socioeconomic circumstancesIntrapartum stillbirthUnexplained stillbirthBereavement careStillbirthCare contributesStillborn childSocioeconomic circumstancesCausal pathwaysAdvantaged counterpartsDisadvantaged familiesEquity gapCareWomen
2015
Predictors of response to 17-alpha hydroxyprogesterone caproate for prevention of recurrent spontaneous preterm birth
Manuck TA, Esplin MS, Biggio J, Bukowski R, Parry S, Zhang H, Huang H, Varner MW, Andrews W, Saade G, Sadovsky Y, Reddy UM, Ilekis J, Research E. Predictors of response to 17-alpha hydroxyprogesterone caproate for prevention of recurrent spontaneous preterm birth. American Journal Of Obstetrics And Gynecology 2015, 214: 376.e1-376.e8. PMID: 26692181, PMCID: PMC4803498, DOI: 10.1016/j.ajog.2015.12.010.Peer-Reviewed Original ResearchConceptsSpontaneous preterm birthPrevious spontaneous preterm birthRecurrent spontaneous preterm birthDelivery gestational ageRecurrent preterm birthPreterm birthSimilar gestational ageGestational ageHydroxyprogesterone caproateSingleton spontaneous preterm birthEarly spontaneous preterm birthFirst-degree family historyPreterm birth preventionHigh-risk womenPlanned secondary analysisPredictors of responseChi-square testPenultimate pregnancyPregnancy characteristicsNeonatal morbidityPregnancy coursePreterm pregnanciesBirth preventionCurrent pregnancyRegression modelsCluster analysis of spontaneous preterm birth phenotypes identifies potential associations among preterm birth mechanisms
Esplin MS, Manuck TA, Varner MW, Christensen B, Biggio J, Bukowski R, Parry S, Zhang H, Huang H, Andrews W, Saade G, Sadovsky Y, Reddy UM, Ilekis J. Cluster analysis of spontaneous preterm birth phenotypes identifies potential associations among preterm birth mechanisms. American Journal Of Obstetrics And Gynecology 2015, 213: 429.e1-429.e9. PMID: 26070700, PMCID: PMC4556543, DOI: 10.1016/j.ajog.2015.06.011.Peer-Reviewed Original ResearchConceptsSpontaneous preterm birthDecidual hemorrhagePlacental dysfunctionProspective case-control multicenter studyCase-control multicenter studyPremature membrane ruptureGroup of womenCommon biologic pathwaysMaternal comorbiditiesPreterm singletonsPreterm birthWeeks' gestationMulticenter studyMaternal stressSecondary analysisBiologic pathwaysFamilial factorsGenetic factorsWomenPhenotypic profileGestationInfectionMembrane ruptureCommon mechanismPhenotypeThe phenotype of spontaneous preterm birth: application of a clinical phenotyping tool
Manuck TA, Esplin MS, Biggio J, Bukowski R, Parry S, Zhang H, Huang H, Varner MW, Andrews W, Saade G, Sadovsky Y, Reddy UM, Ilekis J, Research E. The phenotype of spontaneous preterm birth: application of a clinical phenotyping tool. American Journal Of Obstetrics And Gynecology 2015, 212: 487.e1-487.e11. PMID: 25687564, PMCID: PMC4456184, DOI: 10.1016/j.ajog.2015.02.010.Peer-Reviewed Original ResearchConceptsSpontaneous preterm birthEarly spontaneous preterm birthInfection/inflammationDecidual hemorrhageGestational ageCervical insufficiencyPreterm birthWeeks' gestationPlacental dysfunctionWhite womenMaternal stressSingleton spontaneous preterm birthDelivery gestational ageFinal common pathwayAfrican American womenMaternal comorbiditiesPremature ruptureProspective studyPlanned analysisUterine distentionClinical dataMultiple possible causesGestationHemorrhageComprehensive classification system
2014
Fetal Growth and Risk of Stillbirth: A Population-Based Case–Control Study
Bukowski R, Hansen NI, Willinger M, Reddy UM, Parker CB, Pinar H, Silver RM, Dudley DJ, Stoll BJ, Saade GR, Koch MA, Rowland Hogue CJ, Varner MW, Conway DL, Coustan D, Goldenberg RL, . Fetal Growth and Risk of Stillbirth: A Population-Based Case–Control Study. PLOS Medicine 2014, 11: e1001633. PMID: 24755550, PMCID: PMC3995658, DOI: 10.1371/journal.pmed.1001633.Peer-Reviewed Original ResearchConceptsRisk of stillbirthCase-control studyFetal growthGestational ageLive birthsSevere SGAPopulation-based case-control studyStillbirth prevention strategiesExcessive fetal growthSingleton live birthsFetal growth abnormalitiesNormal fetal growthStillbirth risk factorsGestational age estimatesTiming of deathLGA pregnanciesSingleton stillbirthsIndividualized normsTerm pregnancy
2013
Bile acids in a multicenter, population-based case-control study of stillbirth
Silver RM, Parker CB, Goldenberg R, Reddy UM, Dudley DJ, Saade GR, Hogue CJ, Coustan D, Varner MW, Koch MA, Conway D, Bukowski R, Pinar H, Stoll B, Moore J, Willinger M. Bile acids in a multicenter, population-based case-control study of stillbirth. American Journal Of Obstetrics And Gynecology 2013, 210: 460.e1-460.e9. PMID: 24215860, PMCID: PMC4413928, DOI: 10.1016/j.ajog.2013.11.017.Peer-Reviewed Original ResearchConceptsPopulation-based case-control studyBile acid levelsCase-control studyLive birthsBile acidsStillbirth Collaborative Research NetworkAcid levelsBaseline risk factorsTerm live birthsPopulation-based studyCases of stillbirthTime of enrollmentProportion of womenMaternal serumClinical evidenceIntrahepatic cholestasisRisk factorsFetal anomaliesStillbirthElevated levelsWomenBirthSimilar proportionsCollaborative research networksResearch NetworkStillbirth: Knowledge and Practice among U.S. Obstetrician-Gynecologists
Farrow V, McClure E, Reddy U, Fretts R, Schulkin J, Goldenberg R. Stillbirth: Knowledge and Practice among U.S. Obstetrician-Gynecologists. American Journal Of Perinatology 2013, 30: 813-820. PMID: 23329563, DOI: 10.1055/s-0032-1333407.Peer-Reviewed Original ResearchConceptsRisk factorsStandardized order sheetsU.S. Obstetrician-GynecologistsCauses of stillbirthElevated α-fetoproteinAdvanced maternal ageCause of deathIllicit drug useOBGYN departmentsStillbirth causesStillbirth evaluationStillbirth managementPercent of respondentsMultiple gestationsCigarette smokingMaternal ageObstetrician-GynecologistsAmerican CollegeStillbirthDrug useOrder sheetEffective interventionsMost hospitalsΑ-fetoproteinGrand rounds