A Multi-Site Study to Develop and Validate First Trimester, Circulating Microparticle Biomarkers for Tiered Risk Stratification of Spontaneous Preterm Birth in Nulliparas
Rosenblatt K, Zhang Z, Doss R, Gurnani P, Grobman W, Silver R, Parry S, Reddy U, Cao S, Haas D. A Multi-Site Study to Develop and Validate First Trimester, Circulating Microparticle Biomarkers for Tiered Risk Stratification of Spontaneous Preterm Birth in Nulliparas. American Journal Of Obstetrics And Gynecology 2024 PMID: 38789072, DOI: 10.1016/j.ajog.2024.05.032.Peer-Reviewed Original ResearchIn vitro diagnostic multivariate index assaySpontaneous preterm birthGestational agePreterm birthLow riskModerate riskPrediction of spontaneous preterm birthHR groupRisk ratioHigh riskMonitoring Mothers-to-BeNulliparous Pregnancy Outcomes StudyTrimester of pregnancyMultivariate index assayPregnancy Outcomes StudyNested case-control designStatistically significant differencePregnant patientsWeeks gestationMass spectrometry assayCase-control designRisk stratificationStratify riskMothers-to-beStratification toolStillbirth: we can do better
Silver R, Reddy U. Stillbirth: we can do better. American Journal Of Obstetrics And Gynecology 2024, 231: 152-165. PMID: 38789073, DOI: 10.1016/j.ajog.2024.05.042.Peer-Reviewed Original ResearchResource countriesNon-Hispanic blacksPrevention of stillbirthNon-Hispanic whitesOther Pacific IslanderRate of stillbirthLow-income countriesStillbirth rateStillbirthRisk factorsPacific IslandersGenetic etiologyPlacental assessmentEmotion managementRisk stratificationPreventionUnited StatesPregnancyRiskDisparitiesEpidemiologyCountriesU.S.White