2024
Performance Characteristics of the NeuroEXPLORER, a Next-Generation Human Brain PET/CT Imager
Li H, Badawi R, Cherry S, Fontaine K, He L, Henry S, Hillmer A, Hu L, Khattar N, Leung E, Li T, Li Y, Liu C, Liu P, Lu Z, Majewski S, Matuskey D, Morris E, Mulnix T, Omidvari N, Samanta S, Selfridge A, Sun X, Toyonaga T, Volpi T, Zeng T, Jones T, Qi J, Carson R. Performance Characteristics of the NeuroEXPLORER, a Next-Generation Human Brain PET/CT Imager. Journal Of Nuclear Medicine 2024, 65: jnumed.124.267767. PMID: 38871391, PMCID: PMC11294061, DOI: 10.2967/jnumed.124.267767.Peer-Reviewed Original ResearchPeak noise-equivalent count rateNoise-equivalent count rateTime-of-flight resolutionField of viewCount rateExtended axial field-of-viewTransverse field-of-viewAxial field-of-viewField-of-view centerMini-Derenzo phantomSpatial resolutionTangential spatial resolutionsCount rate performanceContrast recovery coefficientHuman brain PET imagingMeasurements of spatial resolutionNEMA sensitivityEnergy resolutionScatter fractionBrain phantomBackprojection reconstructionBrain PET imagingTime resolutionRadial offsetF-FDG imaging
2023
Markerless head motion tracking and event-by-event correction in brain PET
Zeng T, Lu Y, Jiang W, Zheng J, Zhang J, Gravel P, Wan Q, Fontaine K, Mulnix T, Jiang Y, Yang Z, Revilla E, Naganawa M, Toyonaga T, Henry S, Zhang X, Cao T, Hu L, Carson R. Markerless head motion tracking and event-by-event correction in brain PET. Physics In Medicine And Biology 2023, 68: 245019. PMID: 37983915, PMCID: PMC10713921, DOI: 10.1088/1361-6560/ad0e37.Peer-Reviewed Original ResearchConceptsPoint source studyHead motion correctionSmaller residual displacementMotion correctionIterative closest point (ICP) registration algorithmHead motion trackingSpatial resolutionResidual displacementData-driven evaluation methodHigh spatial resolutionLow noiseMotion trackingStereovision cameraMotion tracking deviceStructured lightEvent correctionBrain positron emission tomography (PET) imagingTracking deviceReconstruction resultsHMT methodPoint cloudsNegative biasReference cloudUMTEvaluation method