TIF1γ Counteracts Ferroptosis to Drive Erythroid Progenitor Differentiation
Rossmann M, Yang S, Abraham B, Wang Y, Young R, Hekimi S, Zon L. TIF1γ Counteracts Ferroptosis to Drive Erythroid Progenitor Differentiation. Blood 2023, 142: 8. DOI: 10.1182/blood-2023-184853.Peer-Reviewed Original ResearchTranscription elongationErythroid differentiationErythroid lineageNucleotide metabolismHematopoietic stem cell differentiationCell fate decisionsGenome-wide expressionChromatin immunoprecipitation analysisOnset of hematopoiesisTranscription regulatory processesErythroid progenitor differentiationStem cell differentiationElectron transport chainInhibitor of ferroptosisTranscriptional intermediary factor 1 gammaEnzyme dihydroorotate dehydrogenaseChromatin factorsSuppressor screenMutant embryosFate decisionsTranscriptome profilingZebrafish embryosProgenitor differentiationLineage differentiationBlood differentiation