A Vesicular Stomatitis Virus-Based Hepatitis B Virus Vaccine Vector Provides Protection against Challenge in a Single Dose
Cobleigh MA, Buonocore L, Uprichard SL, Rose JK, Robek MD. A Vesicular Stomatitis Virus-Based Hepatitis B Virus Vaccine Vector Provides Protection against Challenge in a Single Dose. Journal Of Virology 2010, 84: 7513-7522. PMID: 20504927, PMCID: PMC2897621, DOI: 10.1128/jvi.00200-10.Peer-Reviewed Original ResearchConceptsHepatitis B virusT cell responsesSingle immunizationVaccine vectorVesicular stomatitis virusCD8 T cell responsesCD8 T cell activationSerious worldwide public health problemWorldwide public health problemRecombinant protein immunizationEffective prophylactic vaccineCommon infectious diseasesRecombinant vesicular stomatitis virusSimilar antibody titersPublic health problemRecombinant protein vaccineT cell activationStomatitis virusHBV vaccineLiver diseaseProphylactic vaccinesAntibody titersMultiple dosesProtein immunizationSingle dose