Melissa Hey, PhD
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Contact Info
Yale School of Medicine
P.O. Box 2038
New Haven, CT 06521-8518
United States
About
Titles
Associate Dir, Corporate & Foundation Relations
Education & Training
- PhD
- Yale University, Experimental Pathology
- BA
- Smith College, Biochemistry
Research
Research at a Glance
Publications Timeline
A big-picture view of Melissa Hey's research output by year.
5Publications
202Citations
Publications
2013
A vesicular stomatitis virus-based therapeutic vaccine generates a functional CD8 T cell response to hepatitis B virus in transgenic mice.
Cobleigh MA, Wei X, Robek MD. A vesicular stomatitis virus-based therapeutic vaccine generates a functional CD8 T cell response to hepatitis B virus in transgenic mice. Journal Of Virology 2013, 87: 2969-73. PMID: 23269785, PMCID: PMC3571382, DOI: 10.1128/JVI.02111-12.Peer-Reviewed Original ResearchProtective and pathological properties of IL-22 in liver disease: implications for viral hepatitis.
Cobleigh MA, Robek MD. Protective and pathological properties of IL-22 in liver disease: implications for viral hepatitis. The American Journal Of Pathology 2013, 182: 21-8. PMID: 23159948, DOI: 10.1016/j.ajpath.2012.08.043.Peer-Reviewed Original Research
2012
The immune response to a vesicular stomatitis virus vaccine vector is independent of particulate antigen secretion and protein turnover rate.
Cobleigh MA, Bradfield C, Liu Y, Mehta A, Robek MD. The immune response to a vesicular stomatitis virus vaccine vector is independent of particulate antigen secretion and protein turnover rate. Journal Of Virology 2012, 86: 4253-61. PMID: 22345454, PMCID: PMC3318607, DOI: 10.1128/JVI.05991-11.Peer-Reviewed Original Research
2011
A Proinflammatory Role for Interleukin-22 in the Immune Response to Hepatitis B Virus
Zhang Y, Cobleigh MA, Lian J, Huang C, Booth CJ, Bai X, Robek MD. A Proinflammatory Role for Interleukin-22 in the Immune Response to Hepatitis B Virus. Gastroenterology 2011, 141: 1897-1906. PMID: 21708106, PMCID: PMC3199295, DOI: 10.1053/j.gastro.2011.06.051.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsMeSH KeywordsAcute DiseaseAdultAnimalsCase-Control StudiesDisease Models, AnimalFemaleHepatitis BHepatitis B virusHepatitis B, ChronicHumansImmunity, InnateInterferon-gammaInterleukinsLiverMaleMiceMice, Inbred BALB CMice, Inbred C57BLMice, TransgenicSeverity of Illness IndexTh17 CellsVirus ReplicationConceptsHepatitis B virusHBV transgenic miceIL-22Transgenic miceHBV infectionB virusT cellsImmune responseProinflammatory genesHBV-specific cytotoxic T cellsAntigen-nonspecific inflammatory cellsIL-22-induced expressionVirus replicationAcute HBV infectionSubsequent liver damageCytotoxic T cellsCytokine-based therapiesTh17 cellsLiver inflammationProinflammatory roleInflammatory cellsLiver damagePeripheral bloodSingle doseInflammatory response
2010
A Vesicular Stomatitis Virus-Based Hepatitis B Virus Vaccine Vector Provides Protection against Challenge in a Single Dose ▿
Cobleigh MA, Buonocore L, Uprichard SL, Rose JK, Robek MD. A Vesicular Stomatitis Virus-Based Hepatitis B Virus Vaccine Vector Provides Protection against Challenge in a Single Dose ▿. Journal Of Virology 2010, 84: 7513-7522. PMID: 20504927, PMCID: PMC2897621, DOI: 10.1128/jvi.00200-10.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsHepatitis B virusT cell responsesSingle immunizationVaccine vectorVesicular stomatitis virusCD8 T cell responsesCD8 T cell activationSerious worldwide public health problemWorldwide public health problemRecombinant protein immunizationEffective prophylactic vaccineCommon infectious diseasesRecombinant vesicular stomatitis virusSimilar antibody titersPublic health problemRecombinant protein vaccineT cell activationStomatitis virusHBV vaccineLiver diseaseProphylactic vaccinesAntibody titersMultiple dosesProtein immunizationSingle dose
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Yale School of Medicine
P.O. Box 2038
New Haven, CT 06521-8518
United States