2024
Multicenter Quantification of Radiation Exposure and Associated Risks for Prostatic Artery Embolization in 1476 Patients.
Ayyagari R, Rahman S, Grizzard K, Mustafa A, Staib L, Makkia R, Bhatia S, Bilhim T, Carnevale F, Davis C, Fischman A, Isaacson A, McClure T, McWilliams J, Nutting C, Richardson A, Salem R, Sapoval M, Yu H. Multicenter Quantification of Radiation Exposure and Associated Risks for Prostatic Artery Embolization in 1476 Patients. Radiology 2024, 310: e231877. PMID: 38441098, DOI: 10.1148/radiol.231877.Peer-Reviewed Original ResearchMeSH KeywordsAgedArteriesEmbolization, TherapeuticHumansMaleProstateProstatic HyperplasiaRadiation ExposureRetrospective StudiesConceptsProstatic artery embolizationCumulative air kermaRadiation-related adverse eventsBody mass indexAdverse eventsEffective doseFluoroscopy timeArtery embolizationRadiation doseKerma area product valuesMedian cumulative air kermaMedian effective radiation doseFluoroscopy unitPatient body mass indexRadiation exposureTwo-sample <i>t</i> test wasRadiation dose dataBenign prostatic hyperplasiaFluoroscopy-guided proceduresPatient radiation exposureEffective radiation doseRadiation field areaRadiation effective doseWilcoxon rank sum testInvasive angiographic procedures
2023
A Multiclass Radiomics Method–Based WHO Severity Scale for Improving COVID-19 Patient Assessment and Disease Characterization From CT Scans
Henao J, Depotter A, Bower D, Bajercius H, Todorova P, Saint-James H, de Mortanges A, Barroso M, He J, Yang J, You C, Staib L, Gange C, Ledda R, Caminiti C, Silva M, Cortopassi I, Dela Cruz C, Hautz W, Bonel H, Sverzellati N, Duncan J, Reyes M, Poellinger A. A Multiclass Radiomics Method–Based WHO Severity Scale for Improving COVID-19 Patient Assessment and Disease Characterization From CT Scans. Investigative Radiology 2023, 58: 882-893. PMID: 37493348, PMCID: PMC10662611, DOI: 10.1097/rli.0000000000001005.Peer-Reviewed Original ResearchMeSH KeywordsArtificial IntelligenceCOVID-19Disease ProgressionHumansLungRetrospective StudiesTomography, X-Ray ComputedConceptsCOVID-19 positive patientsClinical Progression ScaleLung lesionsLesion modelDisease severityGround-glass opacitiesCOVID-19 patientsRadiologist assessmentExpert thoracic radiologistsMulticenter cohortPleural effusionDisease extentRetrospective studyDevelopment cohortPatient assessmentTomography scanCT scanSeverity ScalePatient's diseaseTissue lesionsThoracic radiologistsLesionsPatientsRadiomics modelRadiomic featuresPredicting tumor recurrence on baseline MR imaging in patients with early-stage hepatocellular carcinoma using deep machine learning
Kucukkaya A, Zeevi T, Chai N, Raju R, Haider S, Elbanan M, Petukhova-Greenstein A, Lin M, Onofrey J, Nowak M, Cooper K, Thomas E, Santana J, Gebauer B, Mulligan D, Staib L, Batra R, Chapiro J. Predicting tumor recurrence on baseline MR imaging in patients with early-stage hepatocellular carcinoma using deep machine learning. Scientific Reports 2023, 13: 7579. PMID: 37165035, PMCID: PMC10172370, DOI: 10.1038/s41598-023-34439-7.Peer-Reviewed Original ResearchMeSH KeywordsCarcinoma, HepatocellularHumansLiver NeoplasmsMachine LearningMagnetic Resonance ImagingNeoplasm Recurrence, LocalRetrospective Studies
2022
Machine Learning Models for Prediction of Posttreatment Recurrence in Early-Stage Hepatocellular Carcinoma Using Pretreatment Clinical and MRI Features: A Proof-of-Concept Study.
Iseke S, Zeevi T, Kucukkaya AS, Raju R, Gross M, Haider SP, Petukhova-Greenstein A, Kuhn TN, Lin M, Nowak M, Cooper K, Thomas E, Weber MA, Madoff DC, Staib L, Batra R, Chapiro J. Machine Learning Models for Prediction of Posttreatment Recurrence in Early-Stage Hepatocellular Carcinoma Using Pretreatment Clinical and MRI Features: A Proof-of-Concept Study. American Journal Of Roentgenology 2022, 220: 245-255. PMID: 35975886, PMCID: PMC10015590, DOI: 10.2214/ajr.22.28077.Peer-Reviewed Original ResearchMeSH KeywordsCarcinoma, HepatocellularFemaleHumansLiver NeoplasmsMagnetic Resonance ImagingMaleMiddle AgedNeoplasm Recurrence, LocalRetrospective StudiesRisk FactorsConceptsEarly-stage hepatocellular carcinomaLiver transplantHepatocellular carcinomaImaging featuresPosttreatment recurrenceOrgan allocationMean AUCLiver transplant eligibilityPretreatment clinical characteristicsPretreatment MRI examinationsKaplan-Meier analysisKaplan-Meier curvesClinical characteristicsImaging surveillanceTherapy allocationTransplant eligibilityUnderwent treatmentClinical parametersRetrospective studyUnpredictable complicationMRI dataConcept studyPoor survivalClinical impactPretreatment MRICryoablation of Venous Malformations: A Systematic Review
Fish A, Moushey A, Chan SM, Staib L, Marino A, Schlachter T. Cryoablation of Venous Malformations: A Systematic Review. Journal Of Vascular And Interventional Radiology 2022, 33: 993-1000. PMID: 35469956, DOI: 10.1016/j.jvir.2022.04.010.Peer-Reviewed Original ResearchMeSH KeywordsCryosurgeryHumansPainRetrospective StudiesSclerotherapyTreatment OutcomeVascular MalformationsConceptsPain scoresVenous malformationsPercutaneous cryoablationLesion volumeClinical studiesLesion sizePostprocedural pain scoresWeighted mean reductionMajor adverse eventsCases of cryoablationPersistent dysesthesiaPostprocedural changesPostprocedural decreaseRandom effects analysisAdverse eventsPatient characteristicsCryoablation techniqueAdverse outcomesTechnical successComplete resolutionPostprocedural symptomsMean reductionCryoablationPrior treatmentSystematic reviewMR Imaging Biomarkers for the Prediction of Outcome after Radiofrequency Ablation of Hepatocellular Carcinoma: Qualitative and Quantitative Assessments of the Liver Imaging Reporting and Data System and Radiomic Features
Petukhova-Greenstein A, Zeevi T, Yang J, Chai N, DiDomenico P, Deng Y, Ciarleglio M, Haider SP, Onyiuke I, Malpani R, Lin M, Kucukkaya AS, Gottwald LA, Gebauer B, Revzin M, Onofrey J, Staib L, Gunabushanam G, Taddei T, Chapiro J. MR Imaging Biomarkers for the Prediction of Outcome after Radiofrequency Ablation of Hepatocellular Carcinoma: Qualitative and Quantitative Assessments of the Liver Imaging Reporting and Data System and Radiomic Features. Journal Of Vascular And Interventional Radiology 2022, 33: 814-824.e3. PMID: 35460887, PMCID: PMC9335926, DOI: 10.1016/j.jvir.2022.04.006.Peer-Reviewed Original ResearchMeSH KeywordsBiomarkersCarcinoma, HepatocellularCatheter AblationContrast MediaHumansLiver NeoplasmsMagnetic Resonance ImagingRetrospective StudiesConceptsProgression-free survivalPoor progression-free survivalLiver Imaging ReportingHepatocellular carcinomaMR imaging biomarkersRadiomics signatureRadiofrequency ablationRadiomic featuresImaging biomarkersImaging ReportingFirst follow-up imagingMedian progression-free survivalRF ablationEarly-stage hepatocellular carcinomaPretreatment magnetic resonanceFirst-line treatmentMultifocal hepatocellular carcinomaSelection operator Cox regression modelTherapy-naïve patientsEarly-stage diseaseKaplan-Meier analysisCox regression modelLog-rank testFollow-up imagingPrediction of outcomeCumulative diagnostic imaging radiation exposure in premature neonates.
Khattab M, Hagan J, Staib LH, Mustafa A, Goodman TR. Cumulative diagnostic imaging radiation exposure in premature neonates. Journal Of Neonatal-Perinatal Medicine 2022, 15: 95-103. PMID: 33843704, DOI: 10.3233/npm-210726.Peer-Reviewed Original ResearchMeSH KeywordsDiagnostic ImagingHumansInfantInfant, NewbornInfant, PrematureIntensive Care Units, NeonatalRadiation ExposureRetrospective StudiesConceptsLength of stayCumulative effective radiation doseNeonatal intensive care unitIntensive care unitGestational ageBirth weightEffective radiation doseIntestinal perforationCare unitPremature infantsRadiological studiesRadiation doseLevel 4 neonatal intensive care unitRadiation exposureMedian birth weightMedian gestational ageRetrospective chart reviewVulnerable patient populationPredictors of exposureIdentifies risk factorsTotal radiation doseChart reviewPremature neonatesPatient populationRisk factors
2021
Voiding and Storage Domain-Specific Symptom Score Outcomes After Prostate Artery Embolization for Lower Urinary Tract Symptoms and Urinary Retention
Powell T, Staib L, Liu B, Bhatia S, Chai T, Ayyagari R. Voiding and Storage Domain-Specific Symptom Score Outcomes After Prostate Artery Embolization for Lower Urinary Tract Symptoms and Urinary Retention. Urology 2021, 156: 216-224. PMID: 33961894, DOI: 10.1016/j.urology.2021.02.046.Peer-Reviewed Original ResearchConceptsLower urinary tract symptomsProstate artery embolizationBenign prostatic hyperplasiaUrinary tract symptomsLUTS patientsIPSS-VUrinary retentionRetention patientsArtery embolizationTract symptomsTotal International Prostate Symptom ScoreDomain scoresInternational Prostate Symptom ScoreComponent scoresProstate Symptom ScoreSingle centerSymptom scoresLife scoresProstatic hyperplasiaIPSSPatientsPre-PAEQoLMonthsScore outcomes
2020
Creating a Radiology Call Center Hotline and “HOT” Sites: Centralizing Radiology Questions and Cohorting Out-patient Care During the COVID-19 Pandemic
Jang B, Facchini D, Staib L, Fernandez A, Pye S, Goodman RT, Granucci C, Nardecchia N, Pahade JK. Creating a Radiology Call Center Hotline and “HOT” Sites: Centralizing Radiology Questions and Cohorting Out-patient Care During the COVID-19 Pandemic. Current Problems In Diagnostic Radiology 2020, 50: 665-668. PMID: 33036812, PMCID: PMC7519410, DOI: 10.1067/j.cpradiol.2020.09.018.Peer-Reviewed Original ResearchConceptsPatient encountersMost common reasonsCOVID-19 symptomsOut-patient careCOVID-19High-quality patientDate of studyCOVID-19 screeningQuality patientCOVID-19 transmissionX-ray examsCommon reasonRadiology technologistsPatientsCOVID-19 pandemicTime of examImaging sitesCareRadiology operationsExamTotalAutomated detection and delineation of hepatocellular carcinoma on multiphasic contrast-enhanced MRI using deep learning
Bousabarah K, Letzen B, Tefera J, Savic L, Schobert I, Schlachter T, Staib LH, Kocher M, Chapiro J, Lin M. Automated detection and delineation of hepatocellular carcinoma on multiphasic contrast-enhanced MRI using deep learning. Abdominal Radiology 2020, 46: 216-225. PMID: 32500237, PMCID: PMC7714704, DOI: 10.1007/s00261-020-02604-5.Peer-Reviewed Original ResearchMeSH KeywordsCarcinoma, HepatocellularDeep LearningHumansLiver NeoplasmsMagnetic Resonance ImagingRetrospective StudiesConceptsDeep convolutional neural networkAverage false positive rateDice similarity coefficientU-NetDeep learning algorithmsConvolutional neural networkTest setMean Dice similarity coefficientRandom forest classifierDCNN methodDCNN approachDeep learningNet architectureLearning algorithmNeural networkLiver segmentationManual 3D segmentationForest classifierGround truthManual segmentationFalse positive rateCorresponding segmentationSegmentationMultiphasic contrast-enhanced MRIThresholding
2019
Prostatic Artery Embolization Using 100–300-μm Trisacryl Gelatin Microspheres to Treat Lower Urinary Tract Symptoms Attributable to Benign Prostatic Hyperplasia: A Single-Center Outcomes Analysis with Medium-Term Follow-up
Ayyagari R, Powell T, Staib L, Chapiro J, Raja A, Bhatia S, Chai T, Schoenberger S, Devito R. Prostatic Artery Embolization Using 100–300-μm Trisacryl Gelatin Microspheres to Treat Lower Urinary Tract Symptoms Attributable to Benign Prostatic Hyperplasia: A Single-Center Outcomes Analysis with Medium-Term Follow-up. Journal Of Vascular And Interventional Radiology 2019, 31: 99-107. PMID: 31771896, DOI: 10.1016/j.jvir.2019.08.005.Peer-Reviewed Original ResearchMeSH KeywordsAcrylic ResinsAge FactorsAgedAged, 80 and overComorbidityCone-Beam Computed TomographyConnecticutEmbolization, TherapeuticGelatinHumansLower Urinary Tract SymptomsMaleMiddle AgedOrgan SizeParticle SizeProstateProstatic HyperplasiaQuality of LifeRecovery of FunctionRetrospective StudiesRisk FactorsTime FactorsTreatment OutcomeConceptsInternational Prostate Symptom ScoreLower urinary tract symptomsPost-void residualCharlson Comorbidity IndexProstatic artery embolizationProstate gland volumeMedian lobe enlargementBenign prostatic hyperplasiaTrisacryl gelatin microspheresArtery embolizationProstatic hyperplasiaGland volumeAdverse event recordingMedical therapy failureClavien-Dindo classificationProstate Symptom ScoreMedium-term followUrinary tract symptomsLower urinary tractMedium-term outcomesPost-procedure valuesQuality of lifeComorbidity indexTract symptomsConsecutive patientsProstatic Artery Embolization in Nonindex Benign Prostatic Hyperplasia Patients: Single-center Outcomes for Urinary Retention and Gross Prostatic Hematuria
Ayyagari R, Powell T, Staib L, Chapiro J, Perez-Lozada JC, Bhatia S, Chai T, Schoenberger S, Devito R. Prostatic Artery Embolization in Nonindex Benign Prostatic Hyperplasia Patients: Single-center Outcomes for Urinary Retention and Gross Prostatic Hematuria. Urology 2019, 136: 212-217. PMID: 31734349, DOI: 10.1016/j.urology.2019.11.003.Peer-Reviewed Original ResearchConceptsProstatic artery embolizationBenign prostatic hyperplasia patientsProstatic hyperplasia patientsInternational Prostate Symptom ScoreProstatic hematuriaHyperplasia patientsUrinary retentionArtery embolizationPostvoid residualHematuria patientsSingle-center outcomesUrinary retention patientsClavien-Dindo classificationProstate Symptom ScoreQuality of lifeTransfusion rateGross hematuriaSH patientsUrinary infectionBladder irrigationGH patientsSymptom scoresUR patientsBladder tumorsDurable treatmentCase-Control Comparison of Conventional End-Hole versus Balloon-Occlusion Microcatheter Prostatic Artery Embolization for Treatment of Symptomatic Benign Prostatic Hyperplasia
Ayyagari R, Powell T, Staib L, Chapiro J, Schoenberger S, Devito R, Pollak J. Case-Control Comparison of Conventional End-Hole versus Balloon-Occlusion Microcatheter Prostatic Artery Embolization for Treatment of Symptomatic Benign Prostatic Hyperplasia. Journal Of Vascular And Interventional Radiology 2019, 30: 1459-1470. PMID: 31375451, DOI: 10.1016/j.jvir.2019.05.033.Peer-Reviewed Original ResearchConceptsProstatic artery embolizationBenign prostatic hyperplasiaEH groupArtery embolizationSymptomatic improvementAdverse eventsProstatic hyperplasiaInternational Prostate Symptom Score improvementTrial successSymptomatic benign prostatic hyperplasiaBO groupContrast material useProstatic artery anatomySymptom score improvementAdverse event ratesProcedural metricsResidual improvementCase-control comparisonClinical improvementRetrospective reviewArtery anatomyMicrocatheter selectionContrast materialScore improvementEvent rates
2017
Disparities in Care Among Patients With Cardiac Implantable Electronic Devices Undergoing MRI
Cavallo JJ, Zhang Y, Staib LH, Lampert R, Weinreb JC. Disparities in Care Among Patients With Cardiac Implantable Electronic Devices Undergoing MRI. Journal Of The American College Of Radiology 2017, 14: 1566-1571. PMID: 28899705, DOI: 10.1016/j.jacr.2017.07.014.Peer-Reviewed Original ResearchAssessment of a modified technique for air delivery during fluoroscopic-monitored pneumatic intussusception reduction
Jindal G, Graeber BL, Staib LH, Silva CT. Assessment of a modified technique for air delivery during fluoroscopic-monitored pneumatic intussusception reduction. Pediatric Radiology 2017, 47: 1594-1598. PMID: 28681232, DOI: 10.1007/s00247-017-3920-z.Peer-Reviewed Original ResearchMeSH KeywordsChildChild, PreschoolEquipment DesignFemaleFluoroscopyHumansInfantInsufflationIntussusceptionMaleRadiation DosageRetrospective StudiesConceptsAir delivery
2016
Magnetic Resonance Imaging and Sonography in the Diagnosis of Placental Invasion
Balcacer P, Pahade J, Spektor M, Staib L, Copel JA, McCarthy S. Magnetic Resonance Imaging and Sonography in the Diagnosis of Placental Invasion. Journal Of Ultrasound In Medicine 2016, 35: 1445-1456. PMID: 27229131, DOI: 10.7863/ultra.15.07040.Peer-Reviewed Original ResearchIs there an added value of a hepatobiliary phase with gadoxetate disodium following conventional MRI with an extracellular gadolinium agent in a single imaging session for detection of primary hepatic malignancies?
Pahade JK, Juice D, Staib L, Israel G, Cornfeld D, Mitchell K, Weinreb J. Is there an added value of a hepatobiliary phase with gadoxetate disodium following conventional MRI with an extracellular gadolinium agent in a single imaging session for detection of primary hepatic malignancies? Abdominal Radiology 2016, 41: 1270-1284. PMID: 26800701, DOI: 10.1007/s00261-016-0635-9.Peer-Reviewed Original Research
2015
Utility of Magnetic Resonance Imaging in the Evaluation of Intraoperatively Confirmed Pelvic Adhesions
Macer ML, Mathur M, Spektor M, Gysler S, Staib L, Kodaman P, McCarthy S. Utility of Magnetic Resonance Imaging in the Evaluation of Intraoperatively Confirmed Pelvic Adhesions. Journal Of Computer Assisted Tomography 2015, 39: 896-900. PMID: 26466105, DOI: 10.1097/rct.0000000000000302.Peer-Reviewed Original ResearchConceptsMagnetic resonance imagingPelvic adhesionsPositive predictive valuePredictive valueResonance imagingSpecificity of MRIGynecologic abdominal surgeryInstitutional review board-approved retrospective analysisNegative predictive valueAnterior culPosterior culAbdominal surgeryOperative reportsInclusion criteriaRetrospective analysisStudy populationBlinded specialistsMRI sensitivityPatientsImaging
2014
Using SUV as a Guide to 18F-FDG Dose Reduction
Cheng DW, Ersahin D, Staib LH, Della Latta D, Giorgetti A, d’Errico F. Using SUV as a Guide to 18F-FDG Dose Reduction. Journal Of Nuclear Medicine 2014, 55: 1998-2002. PMID: 25453048, DOI: 10.2967/jnumed.114.140129.Peer-Reviewed Original Research
2012
The Utility of I-123 Pretherapy Scan in I-131 Radioiodine Therapy for Thyroid Cancer
Chen MK, Yasrebi M, Samii J, Staib LH, Doddamane I, Cheng DW. The Utility of I-123 Pretherapy Scan in I-131 Radioiodine Therapy for Thyroid Cancer. Thyroid 2012, 22: 304-309. PMID: 22300251, DOI: 10.1089/thy.2011.0203.Peer-Reviewed Original ResearchMeSH KeywordsAdenocarcinoma, PapillaryAdenoma, OxyphilicAdolescentAdultAgedAged, 80 and overCarcinomaCarcinoma, PapillaryFemaleHumansIodine RadioisotopesMaleMiddle AgedNeoplasm MetastasisRadionuclide ImagingRadiopharmaceuticalsRetrospective StudiesThyroid Cancer, PapillaryThyroid NeoplasmsThyroidectomyConceptsPretherapy scansThyroid remnantsLymph nodesDistant metastasisYale-New Haven HospitalLarge thyroid remnantsCervical lymph nodesTime of thyroidectomyAdditional clinical informationNew Haven HospitalNeck uptakeRadioiodine therapyWhole-body imagesEuthyroid statePathology reportsThyroid cancerTreatment protocolLocal lymphClinical informationThyroidectomy specimensPretherapyConfidence intervalsScansThyroidectomyMetastasis