2023
Evaluating the PEN-FAST Clinical Decision-making Tool to Enhance Penicillin Allergy Delabeling
Su C, Belmont A, Liao J, Kuster J, Trubiano J, Kwah J. Evaluating the PEN-FAST Clinical Decision-making Tool to Enhance Penicillin Allergy Delabeling. JAMA Internal Medicine 2023, 183: 883-885. PMID: 37338869, PMCID: PMC10282954, DOI: 10.1001/jamainternmed.2023.1572.Peer-Reviewed Original ResearchAntibiotic choice for Group B Streptococcus prophylaxis in mothers with reported penicillin allergy and associated newborn outcomes
Snider J, Mithal L, Kwah J, Rhodes N, Son M. Antibiotic choice for Group B Streptococcus prophylaxis in mothers with reported penicillin allergy and associated newborn outcomes. BMC Pregnancy And Childbirth 2023, 23: 400. PMID: 37254067, PMCID: PMC10228028, DOI: 10.1186/s12884-023-05697-0.Peer-Reviewed Original ResearchConceptsGroup B streptococcus prophylaxisReported penicillin allergyPenicillin allergyGBS prophylaxisLab drawsNeonatal outcomesNewborn outcomesAntibiotic administrationMedical recordsPregnant individualsIntrapartum group B streptococcus prophylaxisNeonatal intensive care unit admissionDesignThis retrospective cohort studyIntensive care unit admissionSelf-reported penicillin allergyNeonates of mothersCare unit admissionIntrapartum antibiotic prophylaxisRetrospective cohort studyWeeks of gestationMother-infant pairsMother-infant dyadsBeta-lactam antibioticsAntibiotic prophylaxisUnit admissionCephalosporins can be safely administered to patients with verified penicillin allergy
Belmont A, Su C, Kwah J. Cephalosporins can be safely administered to patients with verified penicillin allergy. The Journal Of Allergy And Clinical Immunology In Practice 2023, 11: 2933-2935.e2. PMID: 37245737, DOI: 10.1016/j.jaip.2023.05.027.Peer-Reviewed Original Research
2022
Survey of Obstetric Providers to Assess the Knowledge and Management of a Reported Penicillin Allergy in Pregnant Women
Cate JJM, Burn M, Kwah J, Liao J, Illuzzi J, Reddy U, Son M. Survey of Obstetric Providers to Assess the Knowledge and Management of a Reported Penicillin Allergy in Pregnant Women. American Journal Of Perinatology 2022, 40: 001-008. PMID: 35709740, DOI: 10.1055/a-1877-9970.Peer-Reviewed Original ResearchMeSH KeywordsAnti-Bacterial AgentsDrug HypersensitivityFemaleHumansHypersensitivityParturitionPenicillinsPregnancyPregnant WomenSurveys and QuestionnairesConceptsPenicillin skin testingReported penicillin allergyPenicillin allergyObstetric providersPractice patternsEducational sessionsAllergy knowledgeProvider knowledgeEducational interventionSingle academic medical centerPenicillin allergy delabelingPenicillin allergy evaluationPenicillin allergy testingPercentage of patientsIdentification of patientsClinical practice patternsSmall group educational sessionsAcademic medical centerChi-square testAllergy evaluationPenicillin allergicPerinatal outcomesPregnant patientsDrug allergyAllergy testingOutpatient penicillin allergy evaluation during pregnancy and associated clinical outcomes
Kwah JH, Burn MS, Liao J, Cate J, Son M. Outpatient penicillin allergy evaluation during pregnancy and associated clinical outcomes. American Journal Of Obstetrics & Gynecology MFM 2022, 4: 100674. PMID: 35691578, DOI: 10.1016/j.ajogmf.2022.100674.Peer-Reviewed Original ResearchMeSH KeywordsAnti-Bacterial AgentsDrug HypersensitivityFemaleHumansInfant, NewbornOutpatientsPenicillinsPregnancyRetrospective StudiesConceptsPenicillin allergy evaluationPenicillin allergyPregnant womenAllergy evaluationHospital stayNeonatal outcomesClinical benefitIntensive care unit admissionBirth hospitalization lengthUnverified penicillin allergyCare unit admissionNeonatal adverse outcomesRetrospective cohort studyMedical record reviewPostpartum hospital stayAdditional clinical benefitLarge academic hospitalElectronic medical recordsBeta-lactam antibioticsPostpartum infectionReferred womenUnit admissionMaternal outcomesCohort studyTrue allergy
2020
Clinical factors associated with acute exacerbations of chronic rhinosinusitis
Kwah JH, Somani SN, Stevens WW, Kern RC, Smith SS, Welch KC, Conley DB, Tan BK, Grammer LC, Yang A, Schleimer RP, Peters AT. Clinical factors associated with acute exacerbations of chronic rhinosinusitis. Journal Of Allergy And Clinical Immunology 2020, 145: 1598-1605. PMID: 32004523, PMCID: PMC8177481, DOI: 10.1016/j.jaci.2020.01.023.Peer-Reviewed Original ResearchConceptsFrequent acute exacerbationsChronic rhinosinusitisAcute exacerbationAllergic rhinitisClinical factorsEosinophil countAutoimmune diseasesSignificant health care burdenSinus disease severityRetrospective cohort studySystemic corticosteroid useHealth care burdenHigh-risk phenotypeAntibiotic allergyExacerbation frequencyFrequent exacerbationsSinus symptomsCorticosteroid useCohort studyLower FEVNasal polyposisAntibody deficiencyImpaired qualityImmunologic diseasesOdds ratio
2019
Nasal polyps and rhinosinusitis.
Kwah JH, Peters AT. Nasal polyps and rhinosinusitis. Allergy & Asthma Proceedings 2019, 40: 380-384. PMID: 31690375, DOI: 10.2500/aap.2019.40.4252.Peer-Reviewed Original ResearchMeSH KeywordsAdrenal Cortex HormonesAnti-Bacterial AgentsBacterial InfectionsChronic DiseaseHumansNasal PolypsRhinitisSinusitisConceptsAspirin-exacerbated respiratory diseaseChronic rhinosinusitisNasal polypsNasal congestionEthmoid sinusSinus cavityCiliated columnar epithelial cellsPolyp sizeAcute sinus infectionsTopical nasal steroidsAnterior ethmoid sinusChronic mucosal inflammationAllergic fungal rhinosinusitisMajority of patientsTreatment of choiceParanasal sinus mucosaPosterior ethmoid sinusColumnar epithelial cellsAspirin desensitizationIntranasal corticosteroidsNasal steroidsOral steroidsAcute rhinosinusitisMaintenance therapyPersistent asthma