2018
A univariate perspective of multivariate genome‐wide association analysis
Guo X, Zhu J, Fan Q, He M, Wang X, Zhang H. A univariate perspective of multivariate genome‐wide association analysis. Genetic Epidemiology 2018, 42: 470-479. PMID: 29781551, DOI: 10.1002/gepi.22128.Peer-Reviewed Original ResearchConceptsGenome-wide association studiesMultivariate genome-wide association studyMultivariate genome-wide association analysisGenome-wide association analysisMultiple correlated phenotypesGenetic signalsAssociation studiesCorrelated phenotypesAssociation analysisMultiple phenotypesSingle phenotypePhenotype
2015
Association Tests of Multiple Phenotypes: ATeMP
Guo X, Li Y, Ding X, He M, Wang X, Zhang H. Association Tests of Multiple Phenotypes: ATeMP. PLOS ONE 2015, 10: e0140348. PMID: 26479245, PMCID: PMC4610695, DOI: 10.1371/journal.pone.0140348.Peer-Reviewed Original ResearchConceptsExtensive simulation studyStatistical literatureJoint association analysisMultiPhenSimulation studyEquivalence relationshipProportional odds modelReal case studyMeasurement errorMultivariate methodsOdds modelMultiple intermediate phenotypesJoint analysisMultiple phenotypesExplanatory variablesEquivalenceEstimationDistributionPhenotypic distributionATempSolutionError