2024
Textbook outcome and nomogram-guided approaches for enhancing surgical success in elderly HCC patients: Deciphering the influence of sarcopenia
Lanari J, Lupi A, Billato I, Alessandris R, Crimì F, Caregari S, Pepe A, D’Amico F, Vitale A, Quaia E, Cillo U, Gringeri E. Textbook outcome and nomogram-guided approaches for enhancing surgical success in elderly HCC patients: Deciphering the influence of sarcopenia. Updates In Surgery 2024, 76: 2645-2654. PMID: 39373845, PMCID: PMC11602817, DOI: 10.1007/s13304-024-01992-3.Peer-Reviewed Original ResearchPsoas muscle indexElderly HCC patientsOverall survivalLiver resectionSarcopenic patientsHepatocellular carcinomaTextbook outcomePostoperative complicationsHCC patientsMedian psoas muscle indexAbsence of postoperative complicationsElderly hepatocellular carcinomaInfluence of sarcopeniaHepatocellular carcinoma nodulesPreoperative CT scanAssociated with sarcopeniaHepatocellular carcinoma patientsNon-sarcopenic individualsSarcopenia's impactOncological outcomesClavien-DindoPrognostic factorsSurgical successMuscle indexPostoperative outcomesFull-left/Full-right Liver Splitting With Middle Hepatic Vein and Caval Partition During Dual Hypothermic Oxygenated Machine Perfusion
Cillo U, Lauterio A, Furlanetto A, Canitano N, Polacco M, Buscemi V, De Carlis R, Boetto R, D’Amico F, Bassi D, De Carlis L, Gringeri E. Full-left/Full-right Liver Splitting With Middle Hepatic Vein and Caval Partition During Dual Hypothermic Oxygenated Machine Perfusion. Transplantation 2024, 108: 1417-1421. PMID: 38755751, DOI: 10.1097/tp.0000000000005039.Peer-Reviewed Original ResearchMiddle hepatic veinHypothermic oxygenated machine perfusionOxygenated machine perfusionHepatic veinVena cavaMachine perfusionEffects of ischemia-reperfusion injuryLiver splittingDual hypothermic oxygenated machine perfusionIschemia-reperfusion injuryProlonged cold ischemiaSplit liver transplantationEx situ splittingPediatric patientsVenous reconstructionParenchymal transectionAdult patientsLiver transplantationHepatocellular carcinomaVenous congestionRight graftCold ischemiaVenous outflowProlonged ischemiaImprove outcomesRecurrence and tumor-related death after resection of hepatocellular carcinoma in patients with metabolic syndrome
Berardi G, Cucchetti A, Sposito C, Ratti F, Nebbia M, D’Souza D, Pascual F, Dogeas E, Tohme S, Vitale A, D’Amico F, Alessandris R, Panetta V, Simonelli I, Colasanti M, Russolillo N, Moro A, Fiorentini G, Serenari M, Rotellar F, Zimitti G, Famularo S, Ivanics T, Donando F, Hoffman D, Onkendi E, Essaji Y, Giuliani T, Ben S, Caula C, Rompianesi G, Chopra A, Abu Hilal M, Sapisochin G, Torzilli G, Corvera C, Alseidi A, Helton S, Troisi R, Simo K, Conrad C, Cescon M, Cleary S, Kwon D, Ferrero A, Ettorre G, Cillo U, Geller D, Cherqui D, Serrano P, Ferrone C, Aldrighetti L, Kingham T, Mazzaferro V. Recurrence and tumor-related death after resection of hepatocellular carcinoma in patients with metabolic syndrome. JHEP Reports 2024, 6: 101075. PMID: 38961853, PMCID: PMC11220535, DOI: 10.1016/j.jhepr.2024.101075.Peer-Reviewed Original ResearchLong-term outcomes of liver resectionRecurrence-free survivalTime of recurrenceCancer-specific survivalTumor-related factorsDevelopment of hepatocellular carcinomaHepatocellular carcinomaMetabolic syndromeLong-term survivalRisk factorsOverall survivalImpact survivalResection of hepatocellular carcinomaOutcomes of liver resectionCurative intent approachPost-recurrence survivalPredictors of recurrenceHazard of recurrenceTreatment of recurrenceRisk of recurrenceTumor-related deathLong-term outcomesDesigning future trialsAssociated with deathMedian OSWhat Is the Role of Minimally Invasive Liver Surgery in Treating Patients with Hepatocellular Carcinoma on Cirrhosis?
Vitale A, Angelico R, Sensi B, Lai Q, Kauffmann E, Scalera I, Serenari M, Ginesini M, Romano P, Furlanetto A, D’Amico F. What Is the Role of Minimally Invasive Liver Surgery in Treating Patients with Hepatocellular Carcinoma on Cirrhosis? Cancers 2024, 16: 966. PMID: 38473327, PMCID: PMC10930835, DOI: 10.3390/cancers16050966.Peer-Reviewed Original ResearchMinimally invasive liver surgeryOpen surgeryLiver surgerySignificant cardiovascular riskTrans-arterial approachResection outcomesLaparoscopic ablationResected casesLiver transplantationTreated patientsHepatocellular carcinomaEfficacious therapyCardiovascular riskSurgeryPatientsNarrative reviewTreatment hierarchyCurative techniqueHCCResectionCarcinomaCirrhosisTransplantationTherapyLiver resection versus radiofrequency ablation or trans-arterial chemoembolization for early-stage (BCLC A) oligo-nodular hepatocellular carcinoma: meta-analysis
Romano P, Busti M, Billato I, D’Amico F, Marchegiani G, Pelizzaro F, Vitale A, Cillo U. Liver resection versus radiofrequency ablation or trans-arterial chemoembolization for early-stage (BCLC A) oligo-nodular hepatocellular carcinoma: meta-analysis. BJS Open 2024, 8: zrad158. PMID: 38323881, PMCID: PMC10848305, DOI: 10.1093/bjsopen/zrad158.Peer-Reviewed Original ResearchConceptsBarcelona Clinic Liver CancerTrans-arterial chemoembolizationDisease-free survivalBarcelona Clinic Liver Cancer-A patientsBenefits of LRLiver resectionRadiofrequency ablationHepatocellular carcinomaOS benefitOverall survivalA patientsBarcelona Clinic Liver Cancer ABarcelona Clinic Liver Cancer stageDisease-free survival benefitRisk ratioOutcomes of LRMeta-analysisComparative cohort studyCase-control studyChina Biological Medicine DatabaseHCC patientsCohort studyPrimary outcomeNewcastle-OttawaQuality of studies
2005
Role of blood AFP mRNA and tumor grade in the preoperative prognostic evaluation of patients with hepatocellular carcinoma
Cillo U, Vitale A, Navaglia F, Basso D, Montin U, Bassanello M, D'Amico F, Ciarleglio F, Brolese A, Zanus G, De Pascale V, Plebani M, D'Amico D. Role of blood AFP mRNA and tumor grade in the preoperative prognostic evaluation of patients with hepatocellular carcinoma. World Journal Of Gastroenterology 2005, 11: 6920-6925. PMID: 16437593, PMCID: PMC4717031, DOI: 10.3748/wjg.v11.i44.6920.Peer-Reviewed Original ResearchConceptsTumor gradeHepatocellular carcinomaRadical therapyAFP mRNASurgical therapyMRNA statusPrognostic evaluation of HCC patientsAssessment of tumor gradePrognostic evaluation of patientsDiagnosis of hepatocellular carcinomaNodule sizeDetermination of tumor gradeEvaluation of HCC patientsPreoperative tumor gradeMedian follow-upPercutaneous ablative proceduresTumor-related variablesSignificant survival predictorsPotential prognostic roleCohort of patientsEvaluation of patientsSignificant prognosticatorsPrognostic rolePercutaneous biopsyPerformance status