2024
Recovery From Severe Heart Failure in a Patient With Primary Hyperoxaluria Type 1 After Treatment With Lumasiran, Pyridoxine, and Kidney Transplant
Choi M, Kahl A, Hawkins-van der Cingel G, Noriega M, Klingel K, Doeblin P, Schoenrath F, Eckardt K, Öllinger R, Knauf F, Halleck F. Recovery From Severe Heart Failure in a Patient With Primary Hyperoxaluria Type 1 After Treatment With Lumasiran, Pyridoxine, and Kidney Transplant. Annals Of Internal Medicine Clinical Cases 2024, 3 DOI: 10.7326/aimcc.2023.1428.Peer-Reviewed Original ResearchSevere heart failurePrimary hyperoxaluria type 1Hyperoxaluria type 1Heart failureKidney transplantationType 1
2023
Strikingly conserved gene expression changes of polyamine regulating enzymes among various forms of acute and chronic kidney injury
Sieckmann T, Schley G, Ögel N, Kelterborn S, Boivin F, Fähling M, Ashraf M, Reichel M, Vigolo E, Hartner A, Lichtenberger F, Breiderhoff T, Knauf F, Rosenberger C, Aigner F, Schmidt-Ott K, Scholz H, Kirschner K. Strikingly conserved gene expression changes of polyamine regulating enzymes among various forms of acute and chronic kidney injury. Kidney International 2023, 104: 90-107. PMID: 37121432, DOI: 10.1016/j.kint.2023.04.005.Peer-Reviewed Original ResearchConceptsIschemia-reperfusion injuryKidney injuryKidney pathologyExperimental kidney injuryChronic kidney injuryUnilateral ureteral obstructionForms of injuryPolyamine synthesisCyclosporine treatmentArterial hypertensionKidney transplantationUreteral obstructionKidney levelsTissue injuryTubular castsHealthy kidneysHomeostasis contributesInjuryKidneyExperimental modelKidney cell linePutrescine contentReduced expressionGene expression changesTransplantation
2017
A Successful Approach to Kidney Transplantation in Patients With Enteric (Secondary) Hyperoxaluria
Roodnat J, de Mik-van Egmond A, Visser W, Berger S, van der Meijden W, Knauf F, van Agteren M, Betjes M, Hoorn E. A Successful Approach to Kidney Transplantation in Patients With Enteric (Secondary) Hyperoxaluria. Transplantation Direct 2017, 3: e331. PMID: 29536032, PMCID: PMC5828694, DOI: 10.1097/txd.0000000000000748.Peer-Reviewed Original ResearchGraft functionKidney transplantationEnteric hyperoxaluriaDonor kidneysOxalate depositionLong-term transplant functionEnd-stage renal diseaseHigh-output stomaImmediate graft functionDelayed graft functionFirst kidney transplantKidney transplantation patientsCohort of patientsGlomerular filtration rateKidney transplantation outcomesDeceased donor kidneysCalcium oxalate depositionCause biopsiesTransplant functionTransplantation patientsCommon complicationKidney transplantLate complicationsRenal diseaseIntravenous fluids