2020
Assessment of Plasma Oxalate Concentration in Patients With CKD
Pfau A, Wytopil M, Chauhan K, Reichel M, Coca SG, Aronson PS, Eckardt KU, Knauf F. Assessment of Plasma Oxalate Concentration in Patients With CKD. Kidney International Reports 2020, 5: 2013-2020. PMID: 33163722, PMCID: PMC7609998, DOI: 10.1016/j.ekir.2020.08.029.Peer-Reviewed Original ResearchChronic kidney diseasePlasma oxalate concentrationGerman Chronic Kidney Disease (GCKD) studyChronic Kidney Disease studyObservational cohort studyGlomerular filtration rateLarge patient cohortKidney Disease studyKidney stone diseaseCKD progressionMedian eGFROngoing multicenterCohort studyKidney diseasePatient cohortPresent studyFiltration rateClinical trialsStone diseaseLarge cohortOxalate homeostasisPatientsDisease StudyPlasma samplesMaintenance of samples
2017
A Successful Approach to Kidney Transplantation in Patients With Enteric (Secondary) Hyperoxaluria
Roodnat J, de Mik-van Egmond A, Visser W, Berger S, van der Meijden W, Knauf F, van Agteren M, Betjes M, Hoorn E. A Successful Approach to Kidney Transplantation in Patients With Enteric (Secondary) Hyperoxaluria. Transplantation Direct 2017, 3: e331. PMID: 29536032, PMCID: PMC5828694, DOI: 10.1097/txd.0000000000000748.Peer-Reviewed Original ResearchGraft functionKidney transplantationEnteric hyperoxaluriaDonor kidneysOxalate depositionLong-term transplant functionEnd-stage renal diseaseHigh-output stomaImmediate graft functionDelayed graft functionFirst kidney transplantKidney transplantation patientsCohort of patientsGlomerular filtration rateKidney transplantation outcomesDeceased donor kidneysCalcium oxalate depositionCause biopsiesTransplant functionTransplantation patientsCommon complicationKidney transplantLate complicationsRenal diseaseIntravenous fluids
2016
Oxalate, inflammasome, and progression of kidney disease
Ermer T, Eckardt KU, Aronson PS, Knauf F. Oxalate, inflammasome, and progression of kidney disease. Current Opinion In Nephrology & Hypertension 2016, 25: 363-371. PMID: 27191349, PMCID: PMC4891250, DOI: 10.1097/mnh.0000000000000229.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsChronic kidney diseaseProgressive renal failureRenal inflammationRenal failurePlasma oxalateKidney diseaseInflammasome activationElevated plasma oxalate levelsNOD-like receptor familyProgressive renal damageGlomerular filtration rateMore rapid progressionWarrants clinical trialsPlasma oxalate levelsRenal damageEnteric hyperoxaluriaMacrophage infiltrationIL-1βFiltration rateClinical trialsRapid progressionInflammasome proteinsMice protectsUrinary oxalatePyrin domain