2004
Case-control studies of the effectiveness of vaccines: validity and assessment of potential bias
Shapiro ED. Case-control studies of the effectiveness of vaccines: validity and assessment of potential bias. The Pediatric Infectious Disease Journal 2004, 23: 127-131. PMID: 14872178, DOI: 10.1097/01.inf.0000109248.32907.1d.Peer-Reviewed Original ResearchMeSH KeywordsAntibodies, BacterialBacterial CapsulesBiasCase-Control StudiesChild, PreschoolConfidence IntervalsFemaleHaemophilus InfectionsHaemophilus influenzae type bHaemophilus VaccinesHumansImmunityImmunization ScheduleInfantMalePolysaccharides, BacterialProbabilityReference ValuesReproducibility of ResultsSensitivity and SpecificityTreatment OutcomeVaccinationConceptsEffectiveness of vaccinesCase-control studyInvasive Hib infectionsHib vaccinePneumococcal infectionHib infectionsInvasive infectionsHaemophilus influenzae type bInvasive pneumococcal infectionsInfluenzae type bMonths of ageIdentical study designOverall 34Study 74S. pneumoniaeStreptococcus pneumoniaeVaccineInfectionStudy designHibType BPneumoniaeValid methodCasesPotential bias
1991
The Protective Efficacy of Polyvalent Pneumococcal Polysaccharide Vaccine
Shapiro E, Berg A, Austrian R, Schroeder D, Parcells V, Margolis A, Adair R, Clemens J. The Protective Efficacy of Polyvalent Pneumococcal Polysaccharide Vaccine. New England Journal Of Medicine 1991, 325: 1453-1460. PMID: 1944423, DOI: 10.1056/nejm199111213252101.Peer-Reviewed Original ResearchConceptsInvasive pneumococcal infectionsPneumococcal polysaccharide vaccinePneumococcal vaccineProtective efficacyPneumococcal infectionCase patientsImmunocompetent patientsPolysaccharide vaccineVaccination historyHospital-based case-control studyPolyvalent pneumococcal polysaccharide vaccineSerious pneumococcal infectionsSite of hospitalizationVaccine protective efficacyPolyvalent pneumococcal vaccineCase-control studyProspective surveillanceRandomized trialsSterile sitesPatientsS. pneumoniaeMedical careStreptococcus pneumoniaeVaccineInfection