2021
Brief report: Cannabis and opioid use disorder among heart failure admissions, 2008–2018
Chouairi F, Mullan CW, Ravindra N, Clark KAA, Jaffe EM, Bhinder J, Fuery M, Guha A, Ahmad T, Desai NR. Brief report: Cannabis and opioid use disorder among heart failure admissions, 2008–2018. PLOS ONE 2021, 16: e0255514. PMID: 34591847, PMCID: PMC8483306, DOI: 10.1371/journal.pone.0255514.Peer-Reviewed Original ResearchTrends in transcatheter and surgical aortic valve replacement in the United States, 2008-2018
Clark KA, Chouairi F, Kay B, Reinhardt SW, Miller PE, Fuery M, Mullan CW, Guha A, Ahmad T, Desai NR. Trends in transcatheter and surgical aortic valve replacement in the United States, 2008-2018. American Heart Journal 2021, 243: 87-91. PMID: 34571040, DOI: 10.1016/j.ahj.2021.03.017.Peer-Reviewed Original ResearchEvaluation of Racial and Ethnic Disparities in Cardiac Transplantation
Chouairi F, Fuery M, Clark KA, Mullan CW, Stewart J, Caraballo C, Clarke J, Sen S, Guha A, Ibrahim NE, Cole RT, Holaday L, Anwer M, Geirsson A, Rogers JG, Velazquez EJ, Desai NR, Ahmad T, Miller PE. Evaluation of Racial and Ethnic Disparities in Cardiac Transplantation. Journal Of The American Heart Association 2021, 10: e021067. PMID: 34431324, PMCID: PMC8649228, DOI: 10.1161/jaha.120.021067.Peer-Reviewed Original ResearchConceptsWhite patientsHispanic patientsBlack patientsCardiac transplantationHeart transplantationHigh riskEthnic disparitiesAdult heart recipientsAllocation system changePost-transplant deathPost-transplant mortalityOrgan Sharing databasePost-transplantation deathNew allocation systemHeart recipientsDiabetes mellitusRenal diseaseSharing databaseTransplantation ratesUnited NetworkContemporary outcomesPatientsTransplantationDonor characteristicsStudy periodChanges in Use of Left Ventricular Assist Devices as Bridge to Transplantation With New Heart Allocation Policy
Mullan CW, Chouairi F, Sen S, Mori M, Clark KAA, Reinhardt SW, Miller PE, Fuery MA, Jacoby D, Maulion C, Anwer M, Geirsson A, Mulligan D, Formica R, Rogers JG, Desai NR, Ahmad T. Changes in Use of Left Ventricular Assist Devices as Bridge to Transplantation With New Heart Allocation Policy. JACC Heart Failure 2021, 9: 420-429. PMID: 33714748, DOI: 10.1016/j.jchf.2021.01.010.Peer-Reviewed Original ResearchConceptsDonor heart allocation systemNumber of patientsHeart allocation systemVentricular assist deviceWaitlist survivalAssist deviceNew heart allocation policyLeft ventricular assist deviceAllocation system changePost-transplant mortalityOrgan Sharing databaseOutcomes of patientsPost-transplantation outcomesProportion of patientsTime of transplantContinuous-flow LVADPost-transplantation survivalHeart allocation policyNew allocation systemBaseline recipientStatus 1AHeart transplantationIschemic timeLVAD implantationTransplant listImpact of the new heart allocation policy on patients with restrictive, hypertrophic, or congenital cardiomyopathies
Chouairi F, Mullan CW, Sen S, Mori M, Fuery M, Elder RW, Lesse J, Norton K, Clark KA, Miller PE, Mulligan D, Formica R, Rogers JG, Jacoby D, Maulion C, Anwer M, Geirsson A, Desai NR, Ahmad T. Impact of the new heart allocation policy on patients with restrictive, hypertrophic, or congenital cardiomyopathies. PLOS ONE 2021, 16: e0247789. PMID: 33651802, PMCID: PMC7924739, DOI: 10.1371/journal.pone.0247789.Peer-Reviewed Original ResearchConceptsCongenital heart diseaseAllocation system changeHeart allocation systemNew heart allocation policyNew heart allocation systemTransplantation of patientsOrgan Sharing databasePost-transplantation outcomesPost-transplant survivalTime of transplantationMechanical circulatory supportRate of transplantationNumber of patientsHeart allocation policyNew allocation systemStatus 1ACardiac transplantAdult patientsSharing databaseWaitlist survivalCirculatory supportClinical benefitCongenital cardiomyopathyUnited NetworkCHD patients
2020
United States national trends in comorbidity and outcomes of adult cardiac surgery patients
Mullan CW, Mori M, Pichert MD, Bin Mahmood SU, Yousef S, Geirsson A. United States national trends in comorbidity and outcomes of adult cardiac surgery patients. Journal Of Cardiac Surgery 2020, 35: 2248-2253. PMID: 33448476, DOI: 10.1111/jocs.14764.Peer-Reviewed Original ResearchConceptsMitral valve repair/replacementAortic valve replacementCardiac surgery patientsHospital mortalityLength of staySurgery patientsCardiac surgeryAdult cardiac surgery patientsAdult cardiac surgery proceduresUnited States national trendsValve repair/replacementICD-9 procedure codesCoronary artery bypassCardiac surgery proceduresType of surgeryNational Inpatient SampleICD-9 codesNational trendsCross-sectional analysisCABG/Comorbidity trendsArtery bypassPatient ageValve replacementComorbidity profilesPsychiatric Comorbidity and Outcomes After Left Ventricular Assist Device Implantation for End-Stage Heart Failure
Mullan C, Caraballo C, Ravindra NG, Miller PE, McCullough M, Brown K, Aw TW, Gruen J, Clarke JD, Velazquez EJ, Geirsson A, Mori M, Desai NR, Ahmad T. Psychiatric Comorbidity and Outcomes After Left Ventricular Assist Device Implantation for End-Stage Heart Failure. JACC Heart Failure 2020, 8: 569-577. PMID: 32535119, DOI: 10.1016/j.jchf.2020.03.011.Peer-Reviewed Original ResearchConceptsPsychiatric comorbidityMajor psychiatric illnessNarcotic dependencePsychiatric illnessAdverse eventsHeart failureAlcohol abuseKansas City Cardiomyopathy Questionnaire scoreDrug useVentricular assist device implantationEnd-stage heart failureMechanically Assisted Circulatory SupportAssist device implantationEnd-stage heartRisk of rehospitalizationContinuous-flow LVADRisk of mortalityVulnerable patient populationVentricular assist deviceDevice-related infectionsInteragency RegistryLVAD recipientsSpecific psychiatric conditionsClinical outcomesPatient selectionIncidence and characteristics of hospitalization for proximal aortic surgery for acute syndromes and for aneurysms in the USA from 2005 to 2014
Mullan CW, Mori M, Bin Mahmood SU, Yousef S, Mangi AA, Elefteriades JA, Geirsson A. Incidence and characteristics of hospitalization for proximal aortic surgery for acute syndromes and for aneurysms in the USA from 2005 to 2014. European Journal Of Cardio-Thoracic Surgery 2020, 58: 583-589. PMID: 32163136, DOI: 10.1093/ejcts/ezaa067.Peer-Reviewed Original ResearchMeSH KeywordsAortic Aneurysm, ThoracicAortic DissectionHospitalizationHumansIncidenceRetrospective StudiesSyndromeUnited StatesConceptsAcute aortic syndromeProximal aortic surgeryAortic aneurysm surgeryAortic syndromeAneurysm surgeryAortic surgeryThoracic aortic aneurysm surgeryThoracic aneurysm surgeryNational Inpatient SampleCharacteristics of hospitalizationsEdition diagnosis codesAneurysm populationAneurysm operationsAortic proceduresCardiopulmonary bypassAcute syndromeBlack patientsCardiac operationsDiagnosis codesHospital characteristicsInpatient SampleSociodemographic disparitiesSurgical volumeRetrospective analysisCase volume
2019
Clinical Outcomes After Left Ventricular Assist Device Implantation in Older Adults An INTERMACS Analysis
Caraballo C, DeFilippis EM, Nakagawa S, Ravindra NG, Miller PE, Mezzacappa C, McCullough M, Gruen J, Levin A, Reinhardt S, Mullan C, Ali A, Maurer MS, Desai NR, Ahmad T, Topkara VK. Clinical Outcomes After Left Ventricular Assist Device Implantation in Older Adults An INTERMACS Analysis. JACC Heart Failure 2019, 7: 1069-1078. PMID: 31779930, DOI: 10.1016/j.jchf.2019.10.004.Peer-Reviewed Original ResearchConceptsYears of ageVentricular assist device implantationAssist device implantationOlder adultsElderly patientsLVAD implantationDevice implantationMultivariate Cox proportional hazards regression modelCox proportional hazards regression modelKaplan-Meier survival estimatesMechanically Assisted Circulatory SupportProportional hazards regression modelsMechanical circulatory support technologyPost-LVAD outcomesHeart failure populationLog-rank testingSerum albumin levelPredictors of survivalPost-LVAD implantationHazards regression modelsPredictors of outcomeAge-specific outcomesAntithrombotic regimenDurable MCSINTERMACS AnalysisClinical significance of presenting syndromes on outcome after coronary artery bypass grafting
Bin Mahmood SU, Mori M, Yousef S, Mullan CW, Mangi AA, Geirsson A. Clinical significance of presenting syndromes on outcome after coronary artery bypass grafting. Interdisciplinary CardioVascular And Thoracic Surgery 2019, 30: 243-248. PMID: 31713612, DOI: 10.1093/icvts/ivz259.Peer-Reviewed Original ResearchConceptsAcute coronary syndromeStable ischemic heart diseaseCox proportional hazards modelCoronary artery bypassMid-term survivalIschemic heart diseaseProportional hazards modelPresenting syndromeArtery bypassHeart diseaseHazards modelMortality rateMultivariable Cox proportional hazards modelsMultivariate Cox proportional hazards modelMid-term mortality ratesSingle-center retrospective studyConsecutive CABG operationsMid-term mortalityCongestive heart failurePost-discharge survivalLong-term followIntensive care unitOverall mean durationMore comorbiditiesCABG operationsEffects of blood transfusions on transcatheter aortic valve replacement outcomes
Mullan CW, Pichert MD, Geirsson A. Effects of blood transfusions on transcatheter aortic valve replacement outcomes. Journal Of Thoracic And Cardiovascular Surgery 2019, 158: e181. PMID: 31324423, DOI: 10.1016/j.jtcvs.2019.05.070.Commentaries, Editorials and LettersUS National Trends in the Management and Outcomes of Constrictive Pericarditis: 2005-2014
Mori M, Mullan CW, Bin Mahmood SU, Yousef S, Pelletier KJ, Mangi AA, Geirsson A. US National Trends in the Management and Outcomes of Constrictive Pericarditis: 2005-2014. Canadian Journal Of Cardiology 2019, 35: 1394-1399. PMID: 31493971, DOI: 10.1016/j.cjca.2019.05.015.Peer-Reviewed Original ResearchConceptsConstrictive pericarditisPatient characteristicsNational Inpatient Sample datasetHospital mortality rateOutcomes of patientsProportion of patientsCardiopulmonary bypass useUS national trendsUse of CPBUS Census population estimatesCensus population estimatesPoisson regression modelsCPB useHospital mortalityOperative mortalityComorbid patientsSurgical managementBypass usePericarditisMortality ratePatientsPericardiectomyCohortNational trendsMortality