2024
Treatment of Eating Disorders: Current Status, Challenges, and Future Directions
Grilo C. Treatment of Eating Disorders: Current Status, Challenges, and Future Directions. Annual Review Of Clinical Psychology 2024, 20: 97-123. PMID: 38211625, DOI: 10.1146/annurev-clinpsy-080822-043256.Peer-Reviewed Original ResearchAnorexia nervosaBinge-eating disorderBulimia nervosaEating disordersAdaptive treatment designsPsychological treatmentTreatment researchNervosaTreatment designDisordersBulimiaPharmacological optionsAnorexiaEnhanced outcomesExpected final online publication dateFirst-line approachOnline publication dateMedicationFirst-lineClinical guidanceAnnual ReviewAlternative treatmentRevised estimatesPatientsTreatment
2023
Naltrexone/bupropion for binge‐eating disorder: A randomized, double‐blind, placebo‐controlled trial
Grilo C, Lydecker J, Jastreboff A, Pittman B, McKee S. Naltrexone/bupropion for binge‐eating disorder: A randomized, double‐blind, placebo‐controlled trial. Obesity 2023, 31: 2762-2773. PMID: 37751990, PMCID: PMC10600891, DOI: 10.1002/oby.23898.Peer-Reviewed Original ResearchConceptsNaltrexone/bupropionBinge-eating disorderObesity statusLogistic regressionWeight lossPlacebo-controlled trialWeight loss outcomesPrevalent psychiatric disordersEvidence-based treatmentsPost-treatment assessmentBinge-eating frequencyGreater percentage weight lossMedication outcomesRemission ratePharmacological optionsPlaceboBupropionPsychiatric disordersPercentage weight lossMixed modelsDisordersObesityPatientsSignificant reductionWeight reductionBinge-Eating Disorder Interventions: Review, Current Status, and Implications
Grilo C, Juarascio A. Binge-Eating Disorder Interventions: Review, Current Status, and Implications. Current Obesity Reports 2023, 12: 406-416. PMID: 37439970, PMCID: PMC10528223, DOI: 10.1007/s13679-023-00517-0.Peer-Reviewed Original ResearchConceptsPsychological treatmentSpecific psychological treatmentsEating-disorder psychopathologyEvidence-based treatmentsAdditional pharmacological optionsDisorder interventionsSerious psychiatric problemsBehavioral lifestyle interventionScalable interventionsEffective interventionsFuture researchCBTPsychiatric problemsBingeMixed outcomesInterventionCBTgshModest weight lossRecent findingsResearchPsychopathologyShameLifestyle interventionPharmacological optionsSubstantial morbidity