2017
C/EBPd enables the efficient extravasation of human CCR2+ MAIT cells
Zhang H, Lee C, Too L, Singh S, Tsang H, Kabat J, Singh T, Farber J. C/EBPd enables the efficient extravasation of human CCR2+ MAIT cells. The Journal Of Immunology 2017, 198: 143.10-143.10. DOI: 10.4049/jimmunol.198.supp.143.10.Peer-Reviewed Original ResearchMAIT cellsHuman umbilical vein endothelial cellsT cellsHuman mucosal-associated invariant T (MAIT) cellsMucosal-associated invariant T (MAIT) cellsBZIP transcription factorsResponse to pathogen challengeHuman MAIT cellsCD8+ T cellsExpression of FUT7Activated human umbilical vein endothelial cellsChemokine receptor CCR6Non-redundant roleSelectin ligandsSites of inflammationPathogen challengeTranscription factorsUmbilical vein endothelial cellsMR1-restrictedCD8+Receptor CCR6Efficient extravasationInflamed skinVein endothelial cellsChemokine receptors
2014
Blood monocytes expressing CCR6 and monocyte-derived dendritic cells in dermis and epidermis are critical for IL-23-induced psoriasis-like inflammation in mice (CAM5P.238)
Singh T, Zhang H, Farber J. Blood monocytes expressing CCR6 and monocyte-derived dendritic cells in dermis and epidermis are critical for IL-23-induced psoriasis-like inflammation in mice (CAM5P.238). The Journal Of Immunology 2014, 192: 180.9-180.9. DOI: 10.4049/jimmunol.192.supp.180.9.Peer-Reviewed Original ResearchCCR6-/- miceIL-23 injectionDendritic cellsPsoriasis-like inflammationIL-23Blood monocytesAccumulation of dendritic cellsMonocyte-derived dendritic cellsHuman studiesLangerin-DTR micePsoriasis-like pathologyExpression of CCR6Monocyte-derived cellsLangerin+ cellsInflamed skinMyeloid cellsNon-monocyticIL-22Injected i.Psoriatic skinCCR6InflammationMiceMouse skinMonocytes