2019
Keratinocyte-derived CCL20 orchestrates epidermal localization of IL-17-producing γδ T cells and ILCs to mediate psoriasis-like skin inflammation
Singh T, Lu X, Singh S, Zhang H, Doucet M, Kominsky S, Farber J. Keratinocyte-derived CCL20 orchestrates epidermal localization of IL-17-producing γδ T cells and ILCs to mediate psoriasis-like skin inflammation. The Journal Of Immunology 2019, 202: 183.21-183.21. DOI: 10.4049/jimmunol.202.supp.183.21.Peer-Reviewed Original ResearchIL-17-producingT cellsKnock-in miceIL-17Psoriasis-like skin inflammationGd T cellsExpression of CCL20Expression of IL17Hair folliclesCCR6 ligandIMQ treatmentPsoriatic dermatitisCCR6IL-22Skin inflammationReduce inflammationCCL20Day 4Treated skinInflammationMiceB-defensinsSuperficial epidermisKeratinocytesIMQ
2009
Th17 Cells Are Not Required for Host Defense Against Murine Disseminated Candidiasis, But Are Required for Vaccine-Mediated Protection (132.10)
Lin L, Ibrahim A, Avanesian V, Xu X, Farber J, Fu Y, Baquir B, Spellberg B. Th17 Cells Are Not Required for Host Defense Against Murine Disseminated Candidiasis, But Are Required for Vaccine-Mediated Protection (132.10). The Journal Of Immunology 2009, 182: 132.10-132.10. DOI: 10.4049/jimmunol.182.supp.132.10.Peer-Reviewed Original ResearchCCR6-deficient miceDisseminated candidiasisVaccine-mediated protectionTh17 cellsIL-17Control miceRAls3p-NVaccine efficacyDeficient miceSusceptible to disseminated candidiasisCD4+IL-17+Wild type control miceMurine disseminated candidiasisRecombinant N-terminusLevels of IFNCompare Th1Th1/17 cellsT lymphocytesUnvaccinated miceC. albicansCandidiasisVaccinated miceTail veinTh17Candidal adhesin