2010
Exaggerated IL-23-induced psoriasis-like inflammation in mice lacking CCR4 (135.32)
Hedrick M, Zhang H, Farber J. Exaggerated IL-23-induced psoriasis-like inflammation in mice lacking CCR4 (135.32). The Journal Of Immunology 2010, 184: 135.32-135.32. DOI: 10.4049/jimmunol.184.supp.135.32.Peer-Reviewed Original ResearchCCR4-deficient micePsoriasis-like inflammationT cellsIL-23Deficient miceIL-22Intradermal injection of IL-23Foxp3+ cellsExaggerated inflammatory responseWild-type miceIL-10 family cytokinesPro-inflammatory cytokinesIntramural Research ProgramIL-10 familyTh17 cellsTh2 cellsDendritic cellsIL-17AIL-17FMicroabscess formationChemokine receptorsInjected skinInfiltrating neutrophilsEffector functionsIntradermal injection
2009
Th17 Cells Are Not Required for Host Defense Against Murine Disseminated Candidiasis, But Are Required for Vaccine-Mediated Protection (132.10)
Lin L, Ibrahim A, Avanesian V, Xu X, Farber J, Fu Y, Baquir B, Spellberg B. Th17 Cells Are Not Required for Host Defense Against Murine Disseminated Candidiasis, But Are Required for Vaccine-Mediated Protection (132.10). The Journal Of Immunology 2009, 182: 132.10-132.10. DOI: 10.4049/jimmunol.182.supp.132.10.Peer-Reviewed Original ResearchCCR6-deficient miceDisseminated candidiasisVaccine-mediated protectionTh17 cellsIL-17Control miceRAls3p-NVaccine efficacyDeficient miceSusceptible to disseminated candidiasisCD4+IL-17+Wild type control miceMurine disseminated candidiasisRecombinant N-terminusLevels of IFNCompare Th1Th1/17 cellsT lymphocytesUnvaccinated miceC. albicansCandidiasisVaccinated miceTail veinTh17Candidal adhesin