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Sudhir Perincheri, PhD, MBBS

Assistant Professor of Pathology
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Additional Titles

Director of Digital Pathology, Pathology

About

Titles

Assistant Professor of Pathology

Director of Digital Pathology, Pathology

Biography

I completed my residency in Anatomic Pathology/Clinical Pathology as well as fellowship training in hematopathology, renal and genitourinary pathology in the Departments of Pathology and Laboratory Medicine at Yale. After completing my training, I was recruited as faculty in the department of Pathology where I sign out in the three subspecialties. In addition to these subspecialties, I am also interested in the evolution and application of Digital Pathology as well as Transplant Pathology.

Appointments

Education & Training

Renal/ Genitourinary Pathology Fellow
Yale School of Medicine (2017)
Fellow
Yale-New Haven Hospital (2016)
Resident
Yale- New Haven Hospital (2015)
Resident
Rhode Island Hospital (2012)
PhD
University of Kentucky (2004)
MBBS
Calicut Medical College (1999)

Research

Overview

My graduate work at the University of Kentucky involved use of genetic methods to identify a transcriptional regulator of alpha-fetoprotein. Subsequently I performed post-doctoral research in stem cell biology that was partly funded by the Juvenile Diabetes Research Foundation.

My current research interests are in the field of Pathoogy; specifically in application of emerging tools in anatomic pathology. I collaborate with other faculty in the University in a study applying MultiPhoton Microscopy in renal pathology as well as prostate pathology. I also participate in studies using digital analysis tools in anatomic pathology. I have an active collaboration with a basic science lab investigating mechanisms of transplant rejection.

Medical Subject Headings (MeSH)

Hemic and Immune Systems; Hemic and Lymphatic Diseases; Neoplasms; Urogenital System

Research at a Glance

Yale Co-Authors

Frequent collaborators of Sudhir Perincheri's published research.

Publications

2024

2023

2022

Academic Achievements & Community Involvement

  • activity

    ECOG-ACRIN Multiple Myeloma Committee

  • activity

    ECOG-ACRIN Laboratory Science and Pathology Committee

  • activity

    Meidcal Record and Clinical Information Committee

  • activity

    College of American Pathology Digital and Computational Pathology Committee

  • activity

    Evaluation of a Direct-to-Digital Histology Method for Rapid Evaluation of Kidney Biopsies

Clinical Care

Overview

Sudhir Perincheri, MD, PhD, is a pathologist who specializes in diagnosing different kinds of cancers (including blood cancers) and diseases, as well as kidney disorders. He regularly sees cases that involve a diagnosis of leukemia, lymphoma, lupus nephritis, prostate and testicular cancers, as well as kidney cancers. “In pathology, we diagnosis diseases, but we also think about the underlying mechanical basis—it is an intersection of clinical and basic science,” Dr. Perincheri says. “That’s why pathology is perfect for me.”

While growing up in India, Dr. Perincheri heard stories about his aunt, who became a physician in the United States. “She was a role model for me,” he says.

Dr. Perincheri appreciates the variety available through his different pathology specialties. “For example, I might work with kidney transplant patients and test to see if their body is adjusting well to the transplant,” he says. “The rejection has to be treated as quickly as possible. These are very critical, real-time issues.”

In his collaborative research work, Dr. Perincheri studies possible biomarkers of transplant rejection. Those clues may help researchers understand why rejections happen and find ways of detecting rejection early.

He also works with colleagues to develop better imaging techniques within pathology as the field gradually moves away from examining patient samples on physical glass slides. One example of such a technique—developed by Yale researchers—is a special microscopy technique that creates a digital image of a biopsy without using glass slides which can be evaluated and stored online, Dr. Perincheri says. Eventually, those online databases may allow artificial intelligence algorithms to help doctors more quickly and accurately diagnose diseases.

Clinical Specialties

Pathology

Board Certifications

  • Hematology (Pathology)

    Certification Organization
    AB of Pathology
    Original Certification Date
    2017
  • Anatomic & Clinical Pathology

    Certification Organization
    AB of Pathology
    Original Certification Date
    2016

Get In Touch

Contacts

Locations

  • Renal and EM Laboratory

    Academic Office

    Lauder Hall

    310 Cedar Street, Ste B-20

    New Haven, CT 06510