Sudhir Perincheri, PhD, MBBS
Assistant Professor of PathologyCards
About
Research
Overview
My graduate work at the University of Kentucky involved use of genetic methods to identify a transcriptional regulator of alpha-fetoprotein. Subsequently I performed post-doctoral research in stem cell biology that was partly funded by the Juvenile Diabetes Research Foundation.
My current research interests are in the field of Pathoogy; specifically in application of emerging tools in anatomic pathology. I collaborate with other faculty in the University in a study applying MultiPhoton Microscopy in renal pathology as well as prostate pathology. I also participate in studies using digital analysis tools in anatomic pathology. I have an active collaboration with a basic science lab investigating mechanisms of transplant rejection.
Medical Subject Headings (MeSH)
Academic Achievements & Community Involvement
Clinical Care
Overview
Sudhir Perincheri, MD, PhD, is a pathologist who specializes in diagnosing different kinds of cancers (including blood cancers) and diseases, as well as kidney disorders. He regularly sees cases that involve a diagnosis of leukemia, lymphoma, lupus nephritis, prostate and testicular cancers, as well as kidney cancers. “In pathology, we diagnosis diseases, but we also think about the underlying mechanical basis—it is an intersection of clinical and basic science,” Dr. Perincheri says. “That’s why pathology is perfect for me.”
While growing up in India, Dr. Perincheri heard stories about his aunt, who became a physician in the United States. “She was a role model for me,” he says.
Dr. Perincheri appreciates the variety available through his different pathology specialties. “For example, I might work with kidney transplant patients and test to see if their body is adjusting well to the transplant,” he says. “The rejection has to be treated as quickly as possible. These are very critical, real-time issues.”
In his collaborative research work, Dr. Perincheri studies possible biomarkers of transplant rejection. Those clues may help researchers understand why rejections happen and find ways of detecting rejection early.
He also works with colleagues to develop better imaging techniques within pathology as the field gradually moves away from examining patient samples on physical glass slides. One example of such a technique—developed by Yale researchers—is a special microscopy technique that creates a digital image of a biopsy without using glass slides which can be evaluated and stored online, Dr. Perincheri says. Eventually, those online databases may allow artificial intelligence algorithms to help doctors more quickly and accurately diagnose diseases.
Clinical Specialties
Board Certifications
Hematology (Pathology)
- Certification Organization
- AB of Pathology
- Original Certification Date
- 2017
Anatomic & Clinical Pathology
- Certification Organization
- AB of Pathology
- Original Certification Date
- 2016
News & Links
Media
- MultiPhoton Microscopy image of a kidney biopsy involved by post-infectious glomerulonephritis
News
- September 25, 2024
Pathology Team Encouraged About Migration to Epic Beaker Laboratory Information System
- March 20, 2024
Digital pathology
- March 01, 2024
Connecticut Society of Pathologists' Educational Meeting Draws Pathologists from Across the State
- December 19, 2023
Yale Pathologists Lead Effort to Revitalize Connecticut Society of Pathologists