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Imran Quraishi, MD, PhD

Associate Professor of Neurology
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Contact Info

Yale School of Medicine

P.O. Box 208018

New Haven, CT 06520-8018

United States

Additional Titles

Director, Center for Neurostimulation in Epilepsy

Medical Director, Epilepsy Monitoring Unit

Director, Epilepsy Magnetoencephalography Program

About

Titles

Associate Professor of Neurology

Director, Center for Neurostimulation in Epilepsy; Medical Director, Epilepsy Monitoring Unit; Director, Epilepsy Magnetoencephalography Program

Appointments

Education & Training

Postdoctoral Fellowship in Epilepsy
Yale School of Medicine (2015)
Residency
Yale School of Medicine/Yale-New Haven Hospital (2013)
Internship
UPMC Presbyterian Medical Center (2010)
MD
Baylor College of Medicine (2009)
PhD
Rice University, Bioengineering (2008)
BS
Johns Hopkins University, Biomedical Engineering (Concentrations: Electrical Engineering and Chemical Engineering) (2000)

Research

Overview

Clinical projects

  • Long-term ambulatory recordings from the responsive neurostimulation system (RNS) and thalamic deep brain stimulation (DBS) devices, which are implanted into the brain to treat epilepsy.
  • Clinical trials of brain stimulation to treat epilepsy.
  • Use of intracranial EEG from surgical epilepsy patients and from RNS to study cognitive neuroscience of language and memory.
  • Seizure forecasting based on intracranial EEG biomarkers.
  • Electric and magnetic source localization, including magnetoencephalography (MEG) to understand epilepsy networks.
  • PET imaging with novel tracers to visualize the effects of brain stimulation and brain dysfunction in epilepsy.

Laboratory projects

  • Cellular and animal models of KCNT1 potassium channelopathies
  • Anti-sense oligonucleotides and new medications to treat epilepsy due to KCNT1 mutations

Medical Research Interests

Biomedical Engineering; Channelopathies; Cognitive Neuroscience; Computational Biology; Electric Stimulation; Electroencephalography; Epilepsy; Ion Channels; Neurosciences; Seizures

Research at a Glance

Yale Co-Authors

Frequent collaborators of Imran Quraishi's published research.

Publications

Featured Publications

2024

Clinical Trials

Current Trials

Clinical Care

Overview

Imran H. Quraishi, MD, PhD, is a neurologist who cares for patients with all forms of epilepsy, including those with associated developmental or genetic disorders, as well as patients undergoing evaluation for such advanced treatments as surgery and medical devices. He is devoted to seeking out better treatments. “We want to find out why epilepsy develops and how we can interfere with that process,” he says. “We also look for answers as to why patients with epilepsy develop memory loss and other cognitive difficulties.”

As a Yale School of Medicine researcher, Dr. Quraishi’s main focus is to determine how mutations in ion channel genes contribute to seizures and epilepsy. Drawing on his background in computational modeling and electrophysiology, he is assessing the role of specific ion channels in seizures and how they can be targeted with new medications. He is also applying his expertise to studies of medical devices for the treatment of epilepsy.

Seizures from epilepsy are much more common than most people realize, Dr. Quraishi says. “Most of the time we are able to control seizures and limit side effects for our patients with the appropriate medications. Our goal is to have no seizures and no side effects,” he says.

Clinical Specialties

Epilepsy & Seizures; Neurology

Fact Sheets

Board Certifications

  • Epilepsy

    Certification Organization
    AB of Psychiatry & Neurology
    Original Certification Date
    2016
  • Neurology

    Certification Organization
    AB of Psychiatry & Neurology
    Original Certification Date
    2013

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Contacts

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Mailing Address

Yale School of Medicine

P.O. Box 208018

New Haven, CT 06520-8018

United States

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