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News
New AI tool searches genetic haystacks to find disease-causing variants
Scientists have developed a way to sift through millions of differences in a person’s genetic blueprint to detect those that threaten our health, and have tested the new tool on a biomedical database of more than 450,000 people in the United Kingdom, according to a series of papers published Thursday in the journal Science. The research marks a critical step toward harnessing the full power of the genome for medicine, and it demonstrates a new way artificial intelligence can be applied to problems in human health, experts said.
Source: The Washington Post
1 Jun 2023
News
U.S. study will test whether drug combinations can wipe out tumors
The U.S. government is launching a wide-ranging effort to study whether combining two drugs matched to molecular weak spots in a patient’s tumor will work better to wipe out the cancer than a single such drug. Although cancer drug combinations are nothing new, the National Cancer Institute’s (NCI’s) ComboMATCH study formally announced today is demanding unusually rigorous evidence—in the form of data showing the drug pairs shrink tumors in mice—before letting them move into clinical testing.
Source: Science
1 Jun 2023
News
Chains Overcharging Medicare for Drugs Can Be Sued for Fraud, Supreme Court Rules
The Supreme Court on Thursday said lawsuits could proceed alleging that the supermarket chains Safeway and Supervalu defrauded the government by claiming Medicare and Medicaid reimbursements at list price for drugs that they typically sold to consumers at steeply discounted rates.
Source: The Wall Street Journal
1 Jun 2023
News
More People Should Get This Test to Detect a Deadly Cancer
There is a test that could diminish the toll of the nation’s top cancer killer—if people would use it. Doctors are pushing harder to make that happen.
Source: The Wall Street Journal
1 Jun 2023
News
FDA Warns About Safety of Custom-Made Ozempic
The Food and Drug Administration has warned consumers that it can’t guarantee the safety of custom-made forms of Ozempic and other popular weight-loss drugs.
Source: The Wall Street Journal
1 Jun 2023
News
Hundreds of new primate genomes offer window into human health—and our past
Two international teams have sequenced the genomes of more than 200 nonhuman primates, from palm-size mouse lemurs to 200-kilogram gorillas, and have come up with clues to human health and disease, and to the origin of our species.
Source: Science
1 Jun 2023
News
No One Knows How Many L.G.B.T.Q. Americans Die by Suicide
Studies of L.G.B.T.Q. people show they have high rates of suicidal thoughts and suicide attempts, factors that greatly increase the risk of suicide. But because most death investigators do not collect data on sexuality or gender identity, no one knows how many gay and transgender people die by suicide each year in the United States.
Source: The New York Times
1 Jun 2023
News
Sick Workers Tied to 40% of Food Poisoning Outbreaks, C.D.C. Says
People who showed up to their restaurant jobs while sick were linked to 40 percent of food poisoning outbreaks with a known cause from 2017 to 2019, the Centers for Disease Control and Prevention said in a report released on Tuesday. Paid sick leave and other policies that support sick workers could improve food safety outcomes, according to the report, which was based on a review of 800 food poisoning outbreaks, using data provided by 25 state and local health departments.
Source: The New York Times
1 Jun 2023
News
A catatonic woman awakened after 20 years. Her story may change psychiatry.
New research suggests that a subset of patients with psychiatric conditions such as schizophrenia may actually have autoimmune disease that attacks the brain.
Source: The Washington Post
1 Jun 2023
News
Biden plans to pick physician Mandy Cohen to lead CDC
President Biden plans to select former North Carolina health secretary Mandy Cohen to lead the Centers for Disease Control and Prevention, according to three people with direct knowledge of the pending announcement.
Source: The Washington Post
1 Jun 2023
News
This Nonprofit Health System Cuts Off Patients With Medical Debt
A wealthy nonprofit health system in the Midwest is withholding care from patients who have unpaid medical bills.
Source: The New York Times
1 Jun 2023
News
Appeals court paves way for Purdue Pharma opioids settlement
A federal appeals court Tuesday cleared the way for drug manufacturer Purdue Pharma to settle thousands of lawsuits regarding its role in fueling the opioid epidemic in the United States, reinstating a bankruptcy settlement that controversially shields from future claims the family members who own the company.
Source: The Washington Post
31 May 2023
News
Peru battles record dengue outbreak, in a warning for a warming world
Peru is taking extraordinary measures such as banning households from filling vases with water, as it battles its worst dengue outbreak on record, a crisis that experts have linked to increased rainfall and warmer temperatures as the climate changes. As of Monday, the South American nation has recorded more than 110,000 probable cases of dengue this year, according to its National Center for Epidemiology, Prevention and Control of Diseases.
Source: The Washington Post
31 May 2023
News
Coastal Town Brings Mass Litigation—and an ‘Existential Threat’—to Chemical Giants
Compounds used in firefighting foam seeped into the groundwater in Stuart, Fla. Now it’s at the forefront of thousands of suits against the makers.
Source: The Wall Street Journal
31 May 2023
News
An Inside Look at Covid’s Lasting Damage to the Lungs
The Times analyzed hundreds of millions of data points from three patients’ scans to reconstruct their lungs in 3-D. The resulting visualization offers a vivid, visceral picture of damage that can linger years after infection and irrevocably alter everyday life.
Source: The New York Times
31 May 2023
News
Children die in hot cars in three states, prompting grief and warnings
Three young children — ages 4, 1 and 11 months — died in recent days after being left or becoming trapped in hot cars for hours in Washington state, Texas and Florida, according to authorities.
Source: The Washington Post
31 May 2023
News
How to Lower Deaths Among Women? Give Away Cash.
Cash grants made directly to poor families or individuals have led to fewer deaths among women and young children, according to a new analysis of more than 7 million people in 37 countries. In countries that began making such payments, deaths among women fell by 20 percent, and deaths among children younger than 5 declined by 8 percent, researchers reported on Wednesday in the journal Nature.
Source: The New York Times
31 May 2023
News
AI intensifies fight against ‘paper mills’ that churn out fake research
Advances in artificial intelligence (AI) are complicating publishers’ efforts to tackle the growing problem of paper mills — companies that produce fake scientific papers to order. Generative AI tools, including chatbots such as ChatGPT and image-generating software, provide new ways of producing paper-mill content, which could prove particularly difficult to detect.
Source: Nature
31 May 2023
News
Sacklers Can Be Shielded From Opioid Liability, Appeals Court Rules
Members of the Sackler family, the billionaire owners of Purdue Pharma, will receive full immunity from all civil legal claims — current and future — over their role in the company’s prescription opioids business, a federal appeals court panel ruled on Tuesday. The ruling gives the family the sweeping protection that it has been demanding for years, in exchange for payment of up to $6 billion of the family’s fortune to help address the ongoing ravages of the opioid crisis.
Source: The New York Times
31 May 2023
News
The human brain’s characteristic wrinkles help to drive how it works
The wrinkles that give the human brain its familiar walnut-like appearance have a large effect on brain activity, in much the same way that the shape of a bell determines the quality of its sound, a study suggests. The findings run counter to a commonly held theory about which aspect of brain anatomy drives function.
Source: Nature
31 May 2023