Thuy Tran, MD, PhD
Assistant Professor of Medicine (Medical Oncology)Cards
About
Research
Overview
As a physician-scientist and clinical investigator, my hope is to be able to move bench research efficiency to the clinic. Most importantly, I want to learn from the patients and their experience to inform my studies. My ultimate goal is to improve immune treatment options and quality of life for patients with metastatic malignancies.
My research focuses on understanding and improving clinical targets to overcome resistance to immune therapy. We are actively engaged in studies related to macrophage migration inhibitor factor (MIF) in melanoma as well as understanding complications from brain metastatic disease. I have focused on addressing neurologic complications of brain metastases or its treatment by (1) identifying mediators of metastasis-associated edema that can be given concurrently to further improve brain-active systemic therapies and patient outcomes, (2) identifying key immune cells driving radiation necrosis after treatment with stereotactic radiosurgery, and (3) determining key brain tumor infiltrating immune cell subsets and evaluating their effect on patient response and survival.
Medical Subject Headings (MeSH)
Clinical Care
Overview
Clinical Specialties
Fact Sheets
Merkel Cell Carcinoma (MCC)
Learn More on Yale MedicineBasal Cell Carcinoma (BCC)
Learn More on Yale MedicineSquamous Cell Carcinoma
Learn More on Yale MedicineMelanoma
Learn More on Yale Medicine
Yale Medicine News
Links & Media
News
- August 30, 2024
Yale Study Highlights Unmet Needs for Patients With Melanoma Who Progress or Relapse After Immunotherapy Treatment
- January 04, 2024
Immunotherapy for Metastatic Cancer on the Rise, Even Near End of Life
- May 19, 2023Source: Fox 61
Yale researchers say customized cancer vaccine shows promise
- May 16, 2023Source: The Hartford Courant
CT researchers: Vaccine to fight cancer shows promise using same mRNA technology as COVID drug