2019
Replisome structure suggests mechanism for continuous fork progression and post-replication repair
Yang W, Seidman M, Rupp W, Gao Y. Replisome structure suggests mechanism for continuous fork progression and post-replication repair. DNA Repair 2019, 81: 102658. PMID: 31303546, PMCID: PMC7467748, DOI: 10.1016/j.dnarep.2019.102658.Peer-Reviewed Original ResearchConceptsDiscontinuous DNA synthesisFork progressionBacteriophage T7 replisomeReplication fork helicaseDNA replication forksDNA polymeraseLagging-strand DNA polymerasesReplication fork progressionLeading-strand polymeraseDouble-strand breaksReplication fork reversalDNA synthesisPost-replication repair
2005
Discontinuities in the DNA synthesized in an excision-defective strain of Escherichia coli following ultraviolet irradiation. 1968.
Rupp WD, Howard-Flanders P. Discontinuities in the DNA synthesized in an excision-defective strain of Escherichia coli following ultraviolet irradiation. 1968. DNA Repair 2005, 4: 620-33. PMID: 15889457.Peer-Reviewed Original Research
1998
A specific 3′ exonuclease activity of UvrABC
Gordienko I, Rupp W. A specific 3′ exonuclease activity of UvrABC. The EMBO Journal 1998, 17: 626-633. PMID: 9430653, PMCID: PMC1170412, DOI: 10.1093/emboj/17.2.626.Peer-Reviewed Original Research
1997
UvrAB activity at a damaged DNA site: is unpaired DNA present?
Gordienko I, Rupp W. UvrAB activity at a damaged DNA site: is unpaired DNA present? The EMBO Journal 1997, 16: 880-888. PMID: 9049316, PMCID: PMC1169688, DOI: 10.1093/emboj/16.4.880.Peer-Reviewed Original ResearchMeSH Keywords2-AcetylaminofluoreneAdenosine TriphosphatasesBacterial ProteinsDNA AdductsDNA DamageDNA HelicasesDNA RepairDNA, Single-StrandedDNA-Binding ProteinsEndodeoxyribonucleasesEscherichia coliEscherichia coli ProteinsModels, GeneticMutationNucleic Acid ConformationNucleic Acid DenaturationOligodeoxyribonucleotidesThe limited strand‐separating activity of the UvrAB protein complex and its role in the recognition of DNA damage
Gordienko I, Rupp W. The limited strand‐separating activity of the UvrAB protein complex and its role in the recognition of DNA damage. The EMBO Journal 1997, 16: 889-895. PMID: 9049317, PMCID: PMC1169689, DOI: 10.1093/emboj/16.4.889.Peer-Reviewed Original Research
1994
UvrABC Cutting at 3′ Recessed Termini of Undamaged DNA May Be a Model for 5′ Incision at Damaged Sitesa
RUPP W, GORDIENKO I. UvrABC Cutting at 3′ Recessed Termini of Undamaged DNA May Be a Model for 5′ Incision at Damaged Sitesa. Annals Of The New York Academy Of Sciences 1994, 726: 321-323. PMID: 8092693, DOI: 10.1111/j.1749-6632.1994.tb52839.x.Peer-Reviewed Original Research
1989
In vitro Repair of Psoralen-DNA Cross-links by RecA, UvrABC, and the 5′-Exonuclease of DNA Polymerase I
Sladek FM, Munn MM, Rupp WD, Howard-Flanders P. In vitro Repair of Psoralen-DNA Cross-links by RecA, UvrABC, and the 5′-Exonuclease of DNA Polymerase I. Journal Of Biological Chemistry 1989, 264: 6755-6765. PMID: 2708342, DOI: 10.1016/s0021-9258(18)83494-9.Peer-Reviewed Original Research
1987
Repair of plasmid DNA damaged in vitro with cis- or trans-diamminedichloroplatinum(II) in Escherichia coli
Popoff SC, Beck DJ, Rupp WD. Repair of plasmid DNA damaged in vitro with cis- or trans-diamminedichloroplatinum(II) in Escherichia coli. Mutation Research/Fundamental And Molecular Mechanisms Of Mutagenesis 1987, 183: 129-137. PMID: 3547106, DOI: 10.1016/0167-8817(87)90055-1.Peer-Reviewed Original ResearchConceptsSurvival of plasmidsEscherichia coliPlasmid DNATrans-DDPRecA gene productRepair of plasmidsFunctional recA gene productGene functionUvrABC excinucleaseUvrD mutantsGene productsSOS functionsUntreated plasmidsDeficient strainTransformation frequencyTransformation assaysDNAPlasmidPlatinum adductsColiCis-DDPRepair experimentsCellsExcinucleaseMutants