Thomas Durant, MD
Associate Professor of Laboratory MedicineCards
About
Research
Publications
2024
Accounting for differences between serum and plasma: An indirect approach to derive reference intervals for total protein, albumin, and globulin
Militello L, El-Khoury J, Durant T. Accounting for differences between serum and plasma: An indirect approach to derive reference intervals for total protein, albumin, and globulin. Clinica Chimica Acta 2024, 562: 119851. PMID: 38977172, DOI: 10.1016/j.cca.2024.119851.Peer-Reviewed Original ResearchA primer for quantum computing and its applications to healthcare and biomedical research
Durant T, Knight E, Nelson B, Dudgeon S, Lee S, Walliman D, Young H, Ohno-Machado L, Schulz W. A primer for quantum computing and its applications to healthcare and biomedical research. Journal Of The American Medical Informatics Association 2024, 31: 1774-1784. PMID: 38934288, PMCID: PMC11258415, DOI: 10.1093/jamia/ocae149.Peer-Reviewed Original Research2024 ICBE-B: AI/Predictive Model Verification
Durant T, Seheult JN; College of American Pathologists (CAP) Informatics Committee. 2024 ICBE-B: AI/Predictive Model Verification. Northfield, IL: CAP; 2024.Peer-Reviewed Educational MaterialsBiomarkers vs Machines: The Race to Predict Acute Kidney Injury
Ghazi L, Farhat K, Hoenig M, Durant T, El-Khoury J. Biomarkers vs Machines: The Race to Predict Acute Kidney Injury. Clinical Chemistry 2024, 70: 805-819. PMID: 38299927, DOI: 10.1093/clinchem/hvad217.Peer-Reviewed Original ResearchAcute kidney injuryEarly diagnosisInsulin-like growth factor-binding protein 7Prediction of acute kidney injuryGrowth factor-binding protein 7Detect acute kidney injuryNeutrophil gelatinase-associated lipocalinAcute kidney injury detectionClinical practiceIrreversible kidney damageClinical outcome studiesImminent AKISerum creatinineKidney injuryInjury markersPediatric populationCystatin CTissue inhibitorHospitalized patientsClinical useKidney damageRegulatory approvalProtein 7BiomarkersOutcome studies
2023
Retrospective evaluation of clinical decision support for within-laboratory optimization of SARS-CoV-2 NAAT workflow
Durant T, Peaper D. Retrospective evaluation of clinical decision support for within-laboratory optimization of SARS-CoV-2 NAAT workflow. Journal Of Clinical Microbiology 2023, 62: e00785-23. PMID: 38132702, PMCID: PMC10865785, DOI: 10.1128/jcm.00785-23.Peer-Reviewed Original ResearchData Analytics in Clinical Laboratories: Advancing Diagnostic Medicine in the Digital Age
Merrill A, Durant T, Baron J, Klutts J, Obstfeld A, Peaper D, Stoffel M, Wheeler S, Zaydman M. Data Analytics in Clinical Laboratories: Advancing Diagnostic Medicine in the Digital Age. Clinical Chemistry 2023, 69: 1333-1341. PMID: 37962514, DOI: 10.1093/clinchem/hvad183.Commentaries, Editorials and LettersCybersecurity and Information Assurance for the Clinical Laboratory
Patel A, Williams C, Hart S, Garcia C, Durant T, Cornish T, McClintock D. Cybersecurity and Information Assurance for the Clinical Laboratory. The Journal Of Applied Laboratory Medicine 2023, 8: 145-161. PMID: 36610432, DOI: 10.1093/jalm/jfac119.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsInformation securityInformation assuranceZero-trust security modelSensitive healthcare informationMalicious actorsSecurity modelFuture cyberattacksCybersecurity controlsCybersecurity risksHealthcare informationFuture of healthcareCybersecurityCyberattacksExtended downtimeIntegrated systemSecurityAssurance strategiesPatient dataHealthcare organizationsDowntimePatient care operationsInteroperabilityHigh qualityAssuranceHealthcareThe Roadmap to Interoperability and Laboratory Data: Current State and Next Steps
Chang T, Herman D, McClintock D, Durant T. The Roadmap to Interoperability and Laboratory Data: Current State and Next Steps. The Journal Of Applied Laboratory Medicine 2023, 8: 226-228. PMID: 36610435, DOI: 10.1093/jalm/jfac082.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsFrom Data to Wisdom: Biomedical Knowledge Graphs for Real-World Data Insights
Hänsel K, Dudgeon S, Cheung K, Durant T, Schulz W. From Data to Wisdom: Biomedical Knowledge Graphs for Real-World Data Insights. Journal Of Medical Systems 2023, 47: 65. PMID: 37195430, PMCID: PMC10191934, DOI: 10.1007/s10916-023-01951-2.Commentaries, Editorials and LettersConceptsKnowledge graphReal-world dataGraph modelBiomedical data integrationGraph data modelIntegrated Knowledge GraphBiomedical knowledge graphsElectronic health recordsData integrationData insightsData modelInsight generationBiomedical informationHealth recordsArt researchGraphNovel approachCombination of dataDisease phenotypingInformationPrecision medicine researchHealthcareIntegrationEHRIntriguing opportunity
2022
A preliminary study of hydrocodone and hydromorphone to oxycodone ratios for distinguishing impurities from independent opioid use
Choucair I, Villalba C, Vera M, Cassella-Mclane G, Durant T, El-Khoury J. A preliminary study of hydrocodone and hydromorphone to oxycodone ratios for distinguishing impurities from independent opioid use. Clinical Biochemistry 2022, 112: 6-10. PMID: 36535386, DOI: 10.1016/j.clinbiochem.2022.12.009.Peer-Reviewed Original ResearchConceptsConcentrations of hydrocodoneMean ratioOxycodone pillsPrescription complianceOpioid useUDT resultsMedication recordsOxycodoneAdditional opiatesPatientsHydromorphoneLarger sample sizeAbstractTextHydrocodoneDrug abuseLiquid chromatography-tandem mass spectrometryDrug testingChromatography-tandem mass spectrometryLC-MS/MSFurther validationPreliminary studySample sizeOpiatesSensitive methodPills