2022
Correlation between CD4/CD8 ratio and neurocognitive performance during early HIV infection
Le LT, Price RW, Gisslén M, Zetterberg H, Emu B, Fabre R, Christian P, Andersen S, Spudich S, Vassallo M. Correlation between CD4/CD8 ratio and neurocognitive performance during early HIV infection. HIV Medicine 2022, 24: 442-452. PMID: 36134890, DOI: 10.1111/hiv.13411.Peer-Reviewed Original ResearchConceptsCD4/CD8 ratioPrimary HIV infectionCD8 ratioImmune activationHIV infectionNeuronal injuryAntiretroviral treatmentNeurocognitive performanceMean CD4/CD8 ratioCSF neurofilament light chainART-naïve participantsEarly HIV infectionCerebrospinal fluid markersNeurofilament light chainNeuropsychological testing performancePsychomotor speed performancePHI participantsStudy cohortCSF markersChronic infectionBrain injuryRetrospective analysisFluid markersInfectionInjury
2008
HIV/AIDS of the Central Nervous System
Spudich S. HIV/AIDS of the Central Nervous System. 2008, 430-445. DOI: 10.1016/b978-012373960-5.00019-8.Peer-Reviewed Original ResearchNeurological disordersMajority of HIVPublic health burdenDisease-specific therapiesCentral nervous systemHIV/AIDSAntiretroviral treatmentOpportunistic infectionsPeripheral nervesVascular disordersSpinal cordHealth burdenHIV-1Nervous systemImportant causeNeurological diseasesNutritional diseasesDisordersHIVInfectionAIDSDiseaseDisease epidemicsMorbidityNerve