2021
A Unique Gut Microbiome–Physical Function Axis Exists in Older People with HIV: An Exploratory Study
Dillon SM, Abdo MH, Wilson MP, Liu J, Jankowski CM, Robertson CE, Tuncil Y, Hamaker B, Frank DN, MaWhinney S, Wilson CC, Erlandson KM. A Unique Gut Microbiome–Physical Function Axis Exists in Older People with HIV: An Exploratory Study. AIDS Research And Human Retroviruses 2021, 37: 542-550. PMID: 33787299, PMCID: PMC8260890, DOI: 10.1089/aid.2020.0283.Peer-Reviewed Original ResearchConceptsPhysical functionOlder PWHOlder personsMuscle functionLean massLower short physical performance battery scoresBody compositionShort Physical Performance Battery scoreLower extremity muscle functionPhysical Performance Battery scoreGut microbiomeStool SCFA levelsEffective antiretroviral therapyPhysical function measurementsBetter muscle functionFunction axisAntiretroviral therapySCFA levelsHIV serostatusSPPB scoreUninfected personsSCFA butyrateGrip strengthUninfected controlsPWH
2020
Physical Function and Frailty Tools in Mortality Prediction of Middle-Aged Adults With HIV.
Pelloquin R, Abdo M, MaWhinney S, Jankowski CM, Erlandson KM. Physical Function and Frailty Tools in Mortality Prediction of Middle-Aged Adults With HIV. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2020, 85: 372-378. PMID: 32732769, PMCID: PMC7572796, DOI: 10.1097/qai.0000000000002455.Peer-Reviewed Original ResearchConceptsPhysical function measuresTime-dependent receiverVACS IndexPhysical functionGrip strengthFunction measuresCross-sectional cohort studyPhysical function impairmentPhysical function variablesSex-adjusted modelsHazard of mortalityMiddle-aged populationSpecific patient subpopulationsPrediction of survivalMiddle-aged adultsOnly significant improvementElectronic health recordsVACS scoresCohort studyFrailty toolsFunction impairmentPatient subpopulationsVAC indexMortality predictionPWH