2024
High-impact chronic pain in sickle cell disease: insights from the Pain in Sickle Cell Epidemiology Study (PiSCES).
Jagtiani A, Chou E, Gillespie S, Liu K, Krishnamurti L, McClish D, Smith W, Bakshi N. High-impact chronic pain in sickle cell disease: insights from the Pain in Sickle Cell Epidemiology Study (PiSCES). Pain 2024 PMID: 38787626, DOI: 10.1097/j.pain.0000000000003262.Peer-Reviewed Original ResearchHigh-impact chronic painSickle Cell Epidemiology StudyChronic painProportion of daysUS National Pain StrategySickle cell diseaseNational Pain StrategySelf-care activitiesEpidemiological studiesHigher levels of stressMean pain intensityCohort of individualsPain interferenceLevels of stressPhysical functionHealth outcomesHealthcare utilizationPhysical healthPain strategiesPain burdenPain intensityPain diaryCell diseaseDiary daysAffected subgroups
2022
Effects of Music Therapy on Quality of Life in Adults with Sickle Cell Disease (MUSIQOLS): A Mixed Methods Feasibility Study
Rodgers-Melnick S, Lin L, Gam K, de Santana Carvalho E, Jenerette C, Rowland D, Little J, Dusek J, Bakshi N, Krishnamurti L. Effects of Music Therapy on Quality of Life in Adults with Sickle Cell Disease (MUSIQOLS): A Mixed Methods Feasibility Study. Journal Of Pain Research 2022, 15: 71-91. PMID: 35046718, PMCID: PMC8760983, DOI: 10.2147/jpr.s337390.Peer-Reviewed Original ResearchSickle cell diseaseQuality of lifePreliminary efficacyMT participantsCell diseaseWaitlist controlMusic therapyPROMIS Pain InterferencePROMIS sleep disturbanceMixed methods feasibility studyMusic therapy protocolMethods feasibility studyMusic therapy interventionSelf-management skillsPain interferenceSleep disturbancesTherapy interventionWLC participantsTherapy protocolsDiary completionClinical researchTherapyAdultsEfficacyMixed methods intervention design
2021
Long-Term Quality of Life after Hematopoietic Cell Transplantation for Sickle Cell Disease: A Preliminary Report from the Sickle Cell Transplant Evaluation of Long Term and Late Effects Registry (STELLAR)
Arnold S, Bakshi N, Chang Z, Ross D, Abraham A, Bhatia M, Guilcher G, Haight A, Hsieh M, Kasow K, Lane P, Meacham L, Olowoselu F, Krishnamurti L. Long-Term Quality of Life after Hematopoietic Cell Transplantation for Sickle Cell Disease: A Preliminary Report from the Sickle Cell Transplant Evaluation of Long Term and Late Effects Registry (STELLAR). Blood 2021, 138: 425. DOI: 10.1182/blood-2021-154280.Peer-Reviewed Original ResearchHematopoietic cell transplantationSickle cell diseaseT-scoreSignificant associationTransplant evaluationED visitsHealthcare utilizationPain interferenceCell transplantationCell diseaseRecipients of HCTHLA-identical family donorIdentical family donorLong-term HRQoLFrequency of painEmergency department visitsLong-term survivorsProgressive organ damageChronic persistent painLength of stayAge 18 yearsSAS version 9.4Significant differencesQuality of lifePaucity of data
2018
Pain catastrophizing is associated with poorer health-related quality of life in pediatric patients with sickle cell disease
Bakshi N, Lukombo I, Belfer I, Krishnamurti L. Pain catastrophizing is associated with poorer health-related quality of life in pediatric patients with sickle cell disease. Journal Of Pain Research 2018, 11: 947-953. PMID: 29773954, PMCID: PMC5947835, DOI: 10.2147/jpr.s151198.Peer-Reviewed Original ResearchSickle cell diseasePoor health-related qualityHealth-related qualityHealth care utilizationPoor HRQOLPain intensityCare utilizationCell diseaseDepressive symptomsPrior health care utilizationPsychological factorsPain-related outcomesRace-matched controlsCross-sectional studyQuality of lifePaucity of dataSCD outcomesPain burdenPediatric patientsRed blood cellsPain interferenceMultisystem involvementPain phenotypingHRQoLPsychological covariatesPresence of pain on three or more days of the week is associated with worse patient reported outcomes in adults with sickle cell disease
Bakshi N, Ross D, Krishnamurti L. Presence of pain on three or more days of the week is associated with worse patient reported outcomes in adults with sickle cell disease. Journal Of Pain Research 2018, 11: 313-318. PMID: 29445298, PMCID: PMC5810514, DOI: 10.2147/jpr.s150065.Peer-Reviewed Original ResearchPresence of painSickle cell diseaseChronic SCD painPatient-reported outcomesPain interferenceSCD painMore daysPROMIS scoresChronic painUnadjusted analysesCell diseaseAddiction Clinical Trial Translations Innovations OpportunitiesWorse pain interferenceCore diagnostic criteriaShort-form instrumentEpisodic painPain scoresChronic migraineMajority of daysImpaired qualityProspective studyPhysical functionWorse patientPhysical functioningClinical definition
2014
Feasibility and Tolerability of Quantitative Sensory Testing in Patients with Sickle Cell Disease at the End of a Vasoocclusive Episode
Bakshi N, Lukombo I, Belfer I, Krishnamurti L. Feasibility and Tolerability of Quantitative Sensory Testing in Patients with Sickle Cell Disease at the End of a Vasoocclusive Episode. Blood 2014, 124: 3519. DOI: 10.1182/blood.v124.21.3519.3519.Peer-Reviewed Original ResearchVaso-occlusive episodesQuantitative sensory testingSickle cell diseaseSensory testingCell diseaseVasoocclusive episodesPain intensityAcute vaso-occlusive episodesQST proceduresMapi Research TrustPain Catastrophizing ScalePain Coping InventoryChildren's Somatization InventoryMedian ageChronic painPain interferencePain sensitivityPatient preferencesPain stimuliPain unpleasantnessCold painPROMIS measuresPatient's requestDepressive symptomsThermal pain
2013
Development, Establishment Of the Psychometric Properties and Usability Testing Of a Novel Multi-Dimensional Web Based Diary For Children With Sickle Cell Disease
Bakshi N, Stinson J, Lukombo I, Ross D, Mittal N, Joshi S, Krishnamurti L. Development, Establishment Of the Psychometric Properties and Usability Testing Of a Novel Multi-Dimensional Web Based Diary For Children With Sickle Cell Disease. Blood 2013, 122: 2961. DOI: 10.1182/blood.v122.21.2961.2961.Peer-Reviewed Original ResearchElectronic pain diarySickle cell diseasePain diaryBurden of painPain intensityCell diseaseClinical careHealth care visitsVaso-occlusive crisisPatients ages 15Coordination of careNumerical rating scaleDiary daysEffect of painContent validityElectronic painAdult patientsCare visitsDaily painMusculoskeletal painRelated morbidityPain interferenceCurrent painPain phenotypesClinical trials