Multiomics Investigation of Hypertension and White Matter Hyperintensity as a Source of Vascular Dementia or a Comorbidity to Alzheimer’s Disease
Pathak G, Barber R, Phillips N. Multiomics Investigation of Hypertension and White Matter Hyperintensity as a Source of Vascular Dementia or a Comorbidity to Alzheimer’s Disease. Current Alzheimer Research 2021, 18: 171-177. PMID: 33888050, DOI: 10.2174/1567205018666210422133547.Peer-Reviewed Original ResearchConceptsVascular dementiaAlzheimer's diseaseAbsence of imagingP-tau levelsAge-related comorbiditiesPrevalent age-related conditionProbable vascular dementiaWhite matter hyperintensitiesAge-related conditionsP-tauCSF levelsCSF biomarkersRisk factorsHealthy controlsSignificant gene expression changesClinical dataDifferential diagnosisMatter hyperintensitiesHypertensionAmyloid βUnaffected control populationControl populationMultiomics investigationsDementia profileDiagnostic tests