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Substance Use Disorders (Prevention and Treatment)

Overview

Funded nationally to address substance use disorders, our faculty focuses on advancing innovative treatments and prevention to improve the quality and efficacy of care for patients.

Active Research and Projects

Clinical Trials Network: New England Consortium Node

National Institute on Drug Abuse

Investigators: Gail D'Onofrio, MD, MS, Roger Weiss, MD

The New England Consortium Node consists of a collaboration of esteemed institutions and community treatment providers committed to developing, testing, and disseminating evidence-based treatments in addiction.

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Yale-Drug use, Addiction, and HIV prevention Research Scholars (Yale-DAHRS)

National Institute on Drug Abuse

Investigators: Gail D'Onofrio, MD, MS, Patrick O'Connor, MD, MPH

The Yale-Drug use, Addiction, and HIV prevention Research Scholars program is a K12 sponsored fellowship that provides a comprehensive three-year, post-doctorate, interdisciplinary, mentored career development program. The aim of the program is to prepare investigators for careers focusing on improving medical outcomes for patients with, and at risk for drug use, addiction, and HIV.

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ED-INNOVATION Trial: Emergency Department-INitiated bupreNOrphine and VAlidaTIOn Network Trial

National Institute on Drug Abuse

Investigators: Gail D'Onofrio, MD, MS, David Fiellin, MD

This study will evaluate implementation of emergency department (ED)-initiated BUP in a large number of sites; compare extended release (XR)-BUP with sublingual (SL) BUP in ED patients with untreated OUD; and develop and validate electronic health record phenotypes of opioid-related illnesses to characterize ED visits, enhance active disease surveillance, and better identify patients eligible for study inclusion.