2024
The cytidine deaminase APOBEC3A regulates nucleolar function to promote cell growth and ribosome biogenesis
McCool M, Bryant C, Abriola L, Surovtseva Y, Baserga S. The cytidine deaminase APOBEC3A regulates nucleolar function to promote cell growth and ribosome biogenesis. PLOS Biology 2024, 22: e3002718. PMID: 38976757, PMCID: PMC11257408, DOI: 10.1371/journal.pbio.3002718.Peer-Reviewed Original ResearchRibosome biogenesis factorsRibosome biogenesisBiogenesis factorsCell growthNucleolar functionRegulation of nucleolar functionHuman ribosome biogenesisProtein synthesisProduction of ribosomesFamily of proteinsSource of mutagenesisLevel of protein synthesisCytidine deaminase familyIncreased cell growthPromote cell growthPre-rRNAPotential direct rolePre-mRNATransient overexpressionRibosomeGenomic mutationsBiogenesisMCF10A cellsMaturation stepsAPOBEC3A
2004
A new enrichment approach identifies genes that alter cell cycle progression in Saccharomyces cerevisiae
Bogomolnaya L, Pathak R, Cham R, Guo J, Surovtseva Y, Jaeckel L, Polymenis M. A new enrichment approach identifies genes that alter cell cycle progression in Saccharomyces cerevisiae. Current Genetics 2004, 45: 350-359. PMID: 15022016, DOI: 10.1007/s00294-004-0497-5.Peer-Reviewed Original ResearchConceptsCell cycle progressionCycle progressionSpindle orientation defectsCell size alterationsEnrichment approachNovel enrichment approachMitotic functionsOverall cell proliferationMutant cellsDNA replicationMitotic checkpointCell divisionCell surface depositionSaccharomyces cerevisiaeCell cycleSIK1Cell growthOrientation defectsG1 phaseGenesCell proliferationHxt11PPE1ExpressionCells