2024
Insomnia severity and daytime sleepiness in caregivers of advanced age
Webster L, Ali T, Sharninghausen J, Hajduk A, Gill T, Miner B. Insomnia severity and daytime sleepiness in caregivers of advanced age. Frontiers In Sleep 2024, 3: 1404684. PMID: 39544482, PMCID: PMC11563192, DOI: 10.3389/frsle.2024.1404684.Peer-Reviewed Original ResearchInsomnia Severity IndexNon-caregiversCaregiver statusOlder caregiversPoor self-rated healthSelf-rated healthLow physical activityClinically significant insomnia symptomsSleep disturbanceMultivariable-adjusted modelsRates of depressionRisk of sleep disturbancesInsomnia severityPrevalence of insomniaLevel of insomniaAdvanced ageCaregiver burdenPhysical activityFunctional disabilityCaregiversStandardized questionnaireMultivariate regression analysisInsomnia symptomsPhysical profileCognitive impairment
2023
Associations Between Frailty and the Increased Risk of Adverse Outcomes Among 38,950 UK Biobank Participants With Prediabetes: Prospective Cohort Study
Cao X, Li X, Zhang J, Sun X, Yang G, Zhao Y, Li S, Hoogendijk E, Wang X, Zhu Y, Allore H, Gill T, Liu Z. Associations Between Frailty and the Increased Risk of Adverse Outcomes Among 38,950 UK Biobank Participants With Prediabetes: Prospective Cohort Study. JMIR Public Health And Surveillance 2023, 9: e45502. PMID: 37200070, PMCID: PMC10236284, DOI: 10.2196/45502.Peer-Reviewed Original ResearchConceptsMultiple adverse outcomesChronic kidney diseaseDiabetes-related microvascular diseaseAdverse outcomesCause mortalityCardiovascular diseaseMiddle-aged adultsUK Biobank participantsHigh riskMicrovascular diseaseEye diseaseIncident type 2 diabetes mellitusType 2 diabetes mellitusProportional hazards regression modelsBiobank participantsMultivariable-adjusted modelsProspective cohort studyHazards regression modelsNormal glucose metabolismDiabetes-related burdenDiabetes-related diseasesHealth care resourcesNonfrail counterpartsFrailty assessmentCohort studyAssociation of frailty with the incidence risk of cardiovascular disease and type 2 diabetes mellitus in long-term cancer survivors: a prospective cohort study
Cao X, Yang Z, Li X, Chen C, Hoogendijk E, Zhang J, Yao N, Ma L, Zhang Y, Zhu Y, Zhang X, Du Y, Wang X, Wu X, Gill T, Liu Z. Association of frailty with the incidence risk of cardiovascular disease and type 2 diabetes mellitus in long-term cancer survivors: a prospective cohort study. BMC Medicine 2023, 21: 74. PMID: 36829175, PMCID: PMC9951842, DOI: 10.1186/s12916-023-02774-1.Peer-Reviewed Original ResearchConceptsLong-term cancer survivorsType 2 diabetes mellitusCancer survivorsCardiovascular diseaseIncidence riskDiabetes mellitusFrailty IndicatorCox proportional hazards regression modelRisk of CVDProportional hazards regression modelsNon-frail participantsSerious healthcare burdenIncident cardiovascular diseaseMultivariable-adjusted modelsProspective cohort studyAssociation of frailtyPrimary care dataHazards regression modelsTime of recruitmentQuality of lifeLater comorbidityIncident T2DMCohort studyFrailty phenotypeFrailty index