2018
Use of Renin Angiotensin System Blockers After Acute Kidney Injury: Balancing Tradeoffs.
Alpern RJ, Peixoto AJ. Use of Renin Angiotensin System Blockers After Acute Kidney Injury: Balancing Tradeoffs. JAMA Internal Medicine 2018, 178: 1690-1692. PMID: 30422208, DOI: 10.1001/jamainternmed.2018.4757.Peer-Reviewed Original ResearchAcute Kidney InjuryAngiotensin Receptor AntagonistsAngiotensin-Converting Enzyme InhibitorsHumansRenin-Angiotensin System
1998
Converting enzyme inhibition causes hypocitraturia independent of acidosis or hypokalemia
Melnick J, Preisig P, Haynes S, Pak C, Sakhaee K, Alpern R. Converting enzyme inhibition causes hypocitraturia independent of acidosis or hypokalemia. Kidney International 1998, 54: 1670-1674. PMID: 9844143, DOI: 10.1046/j.1523-1755.1998.00150.x.Peer-Reviewed Original ResearchMeSH KeywordsAcidosisAdultAngiotensin IIAngiotensin-Converting Enzyme InhibitorsAnimalsCitric AcidEnalaprilFemaleHumansHypokalemiaMaleRatsRats, Sprague-DawleyConceptsUrinary citrate excretionCitrate excretionUrinary citrateMetabolic acidosisATP-citrate lyaseEffects of enalaprilRenal citrate metabolismUrine citrate concentrationRenal cortical tissueChronic metabolic acidosisProximal tubular cellsPlasma pHNa/H antiporterAngiotensin IIIntracellular acidosisEnalaprilTubular cellsCitrate lyaseHypokalemiaEnzyme inhibitorsATP citrate lyase activityAcidosisCortical tissueRatsCitrate metabolism