2024
Associations between fasting glucose rate-of-change and the missense variant, rs373863828, in an adult Samoan cohort
Rivara A, Russell E, Carlson J, Pomer A, Naseri T, Reupena M, Manna S, Viali S, Minster R, Weeks D, DeLany J, Kershaw E, McGarvey S, Hawley N. Associations between fasting glucose rate-of-change and the missense variant, rs373863828, in an adult Samoan cohort. PLOS ONE 2024, 19: e0302643. PMID: 38829901, PMCID: PMC11146712, DOI: 10.1371/journal.pone.0302643.Peer-Reviewed Original ResearchConceptsType 2 diabetesAllele of rs373863828Body mass indexFasting glucoseAdult SamoansDevelopment of type 2 diabetesOdds of type 2 diabetesReduction of modifiable risk factorsRs373863828 genotypeAssociated with higher body mass indexType 2 diabetes developmentGlucose rate of changeMass indexHousehold asset scoreUrbanization of residenceHigher body mass indexRisk factorsModifiable risk factorsRate of changeBaseline variablesMultivariate linear regressionPhysical activityDiabetes preventionType 2 diabetes mellitusSmoking statusAccelerometer-Based Estimates of Physical Activity and Sedentary Time Among Samoan Adults.
Hawley N, Zarei P, Crouter S, Desai M, Pomer A, Rivara A, Naseri T, Reupena M, Viali S, Duckham R, McGarvey S. Accelerometer-Based Estimates of Physical Activity and Sedentary Time Among Samoan Adults. Journal Of Physical Activity And Health 2024, 21: 636-644. PMID: 38621669, DOI: 10.1123/jpah.2023-0590.Peer-Reviewed Original ResearchModerate to vigorous physical activityVigorous physical activityEstimates of physical activityPhysical activitySamoan adultsSedentary timeLight physical activityPhysical activity levelsAccelerometer-based devicesModifiable risk factorsClass II/III obesitySedentary activitiesWeight statusHealthy weightAdult SamoansParticipant characteristicsObesity-related diseasesCardiometabolic diseasesCensus regionActivity levelsGeneralized linear modelRural areasObesity-related cardiometabolic diseasesRisk factorsAdults
2022
Associations between diabetes-related symptoms, glycemic control, and health-related quality of life in adult Samoans
Rivara A, Pomer A, Wetzel A, Viali S, Naseri T, Reupena M, Kershaw E, McGarvey S, Hawley N. Associations between diabetes-related symptoms, glycemic control, and health-related quality of life in adult Samoans. Pacific Health Dialog 2022, 21: 638-655. DOI: 10.26635/phd.2022.142.Peer-Reviewed Original ResearchHealth-related qualityDiabetes-related symptomsGlycemic controlAdult SamoansSymptom presenceDiabetes self-care behaviorsSymptom checklist questionnairesHigh symptom burdenDiabetes-related complicationsMultivariate logistic regressionType 2 diabetesSelf-care behaviorsMann-Whitney U testEarly evaluationChi-square testSymptom burdenDiabetes statusCommon symptomsDiabetes symptomsWhitney U testHeart painSeries of anthropometricHigh prevalenceDiabetes experiencePrediabetesThe protective effect of rs373863828 on type 2 diabetes does not operate through a body composition pathway in adult Samoans
Hawley NL, Duckham RL, Carlson JC, Naseri T, Reupena MS, Lameko V, Pomer A, Wetzel A, Selu M, Lupematisila V, Unasa F, Vesi L, Fatu T, Unasa S, Faasalele‐Savusa K, Rivara AC, Russell E, Delany JP, Viali S, Kershaw EE, Minster RL, Weeks DE, McGarvey ST. The protective effect of rs373863828 on type 2 diabetes does not operate through a body composition pathway in adult Samoans. Obesity 2022, 30: 2468-2476. PMID: 36284436, PMCID: PMC10111239, DOI: 10.1002/oby.23559.Peer-Reviewed Original ResearchConceptsFat-free massType 2 diabetesFat distributionProtective effectBody compositionFavorable body fat distributionDual-energy X-ray absorptiometry-derived body compositionBody fat distributionGreater fat-free massPercent body fatBody size/compositionAssociation of genotypesRs373863828 genotypeVisceral adiposityHigher BMIAdult SamoansRole of fatGreater BMILean massBody fatLower oddsParadoxical associationTissue-specific mechanismsA alleleDiabetes
2021
C‐reactive protein in adult Samoans: Population variation and physiological correlates
Rivara AC, Corley M, Choy CC, Duckham RL, Pomer A, Reupena MS, Viali S, Naseri T, Kershaw EE, Crouter SE, McGarvey ST, Bribiescas RG, Valeggia C, Hawley NL. C‐reactive protein in adult Samoans: Population variation and physiological correlates. American Journal Of Human Biology 2021, 34: e23646. PMID: 34260111, PMCID: PMC8758804, DOI: 10.1002/ajhb.23646.Peer-Reviewed Original ResearchConceptsC-reactive proteinBody mass indexCardiometabolic disease riskMeasures of adiposityAdult SamoansCRP correlateDisease riskSerum C-reactive proteinMeasures of BMICardiometabolic risk markersPercent body fatSex-dependent associationsCardiometabolic markersCardiometabolic riskCRP quartileMass indexUnadjusted analysesRisk markersBody fatKruskal-Wallis testAdiposityPacific Islander populationsSpearman rank correlationFirst examinationRank correlation1108-P: Care Cascade Engagement and Characteristics of Diabetes Awareness in Adult Samoans in 2010 and 2018
RIVARA A, RUSSELL E, VIALI S, REUPENA M, NASERI T, POMER A, MINSTER R, WEEKS D, MCGARVEY S, HAWLEY N. 1108-P: Care Cascade Engagement and Characteristics of Diabetes Awareness in Adult Samoans in 2010 and 2018. Diabetes 2021, 70 DOI: 10.2337/db21-1108-p.Peer-Reviewed Original ResearchGlycemic controlMedication useDiabetes awarenessAdult SamoansUnmet needSocioeconomic positionCare cascadeLifestyle scoreDiabetes prevalenceHigher BMICare engagementDiabetes careHigher oddsDisease awarenessLower oddsGreater oddsLogistic regressionDiabetesDoctor's diagnosisTime pointsNational InstituteOddsGenetic variantsDiagnosisCareBody size and composition of Samoan toddlers aged 18–25 months in 2019
Oyama S, Duckham RL, Arslanian KJ, Kershaw EE, Strayer JA, Fidow UT, Naseri T, Hawley NL. Body size and composition of Samoan toddlers aged 18–25 months in 2019. Annals Of Human Biology 2021, 48: 346-349. PMID: 34340601, PMCID: PMC9912174, DOI: 10.1080/03014460.2021.1951351.Peer-Reviewed Original ResearchConceptsDual-energy X-ray absorptiometryProspective birth cohortPrimary study aimX-ray absorptiometryGreater linear growthMother-infant dyadsThigh skinfold thicknessRs373863828 genotypeAdult SamoansArm circumferenceAbdominal circumferenceHead circumferenceProtective effectGG genotypeIliac crestLower riskSkinfold thicknessBody compositionBirth cohortStudy aimMinor alleleEarly lifeMissense variantsCircumferenceEarly childhood
2020
Assessing the impact of high blood pressure referrals on hypertension awareness and management, BMI, and blood pressure values in adult Samoans 2010–2019
Rivara AC, Pomer A, Naseri T, Reupena MS, Viali S, Choy CC, McGarvey ST, Hawley NL. Assessing the impact of high blood pressure referrals on hypertension awareness and management, BMI, and blood pressure values in adult Samoans 2010–2019. Annals Of Human Biology 2020, 47: 597-601. PMID: 32924611, PMCID: PMC8180238, DOI: 10.1080/03014460.2020.1822914.Peer-Reviewed Original ResearchConceptsElevated blood pressureBody mass indexBlood pressureNon-communicable diseasesMedication usePhysician diagnosisRisk factorsLong-term health improvementsHypertension medication useBlood pressure valuesNCD risk factorsHypertension controlCardiometabolic healthHypertension awarenessMass indexAdult SamoansHealth referralsDisease burdenReduced oddsBP valuesSamoan adultsReferralLogistic regressionHealth sector actorsMcNemar test