2023
Brain Networks and Adolescent Alcohol Use
Yip S, Lichenstein S, Liang Q, Chaarani B, Dager A, Pearlson G, Banaschewski T, Bokde A, Desrivières S, Flor H, Grigis A, Gowland P, Heinz A, Brühl R, Martinot J, Martinot M, Artiges E, Nees F, Orfanos D, Paus T, Poustka L, Hohmann S, Millenet S, Fröhner J, Smolka M, Vaidya N, Walter H, Whelan R, Schumann G, Garavan H. Brain Networks and Adolescent Alcohol Use. JAMA Psychiatry 2023, 80: 1131-1141. PMID: 37647053, PMCID: PMC10469292, DOI: 10.1001/jamapsychiatry.2023.2949.Peer-Reviewed Original ResearchConceptsAlcohol Use Disorders Identification TestAlcohol use riskAlcohol misuseUse riskAlcohol use disorderMale adolescentsDisorders Identification TestSingle-site studyIntervention effortsWhole-brain patternsMean ageAlcohol use dataLeading causeMagnetic resonance imaging dataMAIN OUTCOMEReward-related processesHigh riskSeparate cohortUse disordersAlcohol consumptionCurrent severityAdolescent neurodevelopmentAlcohol use behaviorsAlcohol useAUDIT scores
2017
Heavy Drinking in College Students Is Associated with Accelerated Gray Matter Volumetric Decline over a 2 Year Period
Meda SA, Dager AD, Hawkins KA, Tennen H, Raskin S, Wood RM, Austad CS, Fallahi CR, Pearlson GD. Heavy Drinking in College Students Is Associated with Accelerated Gray Matter Volumetric Decline over a 2 Year Period. Frontiers In Behavioral Neuroscience 2017, 11: 176. PMID: 29033801, PMCID: PMC5627037, DOI: 10.3389/fnbeh.2017.00176.Peer-Reviewed Original ResearchAbstainers/light drinkersHeavy drinking groupBrain regionsLight drinkersDrinking groupHeavy drinkingSignificant public health issueSignificant GMV decreaseGray matter changesYear followup periodHarmful alcohol usePublic health issueMedial frontal gyrusLongitudinal effectsFollowup periodGMV decreaseMean agePoints 24 monthsBrain MRIMatter changesNeurodevelopmental periodAlcohol consumptionAnterior cingulateTissue lossHeavy drinkers