2017
The effect of high-dose atorvastatin on neural activity and cognitive function
Taylor BA, Dager AD, Panza GA, Zaleski AL, Meda S, Book G, Stevens MC, Tartar S, White CM, Polk DM, Pearlson GD, Thompson PD. The effect of high-dose atorvastatin on neural activity and cognitive function. American Heart Journal 2017, 197: 166-174. PMID: 29447778, PMCID: PMC6083849, DOI: 10.1016/j.ahj.2017.10.027.Peer-Reviewed Original ResearchConceptsFunctional magnetic resonance imagingGreater activationStroop color-word scoresHopkins Verbal Learning Test-RevisedFigural memory tasksStandard neuropsychological assessmentColor-Word scoreStandard neuropsychological testsBrain activation patternsNeuropsychological test scoresSternberg taskBrain neural activationMemory taskFMRI taskTask versionsNeuropsychological testsNeural activationNeuropsychological assessmentCognitive testingEffect of statinsCognitive functionSignificant group-time interactionNeural activityBilateral precuneusClock Test
2013
fMRI response during figural memory task performance in college drinkers
Dager AD, Jamadar S, Stevens MC, Rosen R, Jiantonio-Kelly RE, Sisante JF, Raskin SA, Tennen H, Austad CS, Wood RM, Fallahi CR, Pearlson GD. fMRI response during figural memory task performance in college drinkers. Psychopharmacology 2013, 231: 167-179. PMID: 23949205, PMCID: PMC3877735, DOI: 10.1007/s00213-013-3219-1.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAlcohol DrinkingAlcoholismBrain MappingData Interpretation, StatisticalFemaleFrontal LobeHippocampusHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingMaleMemoryOxygenParietal LobePsychomotor PerformanceReaction TimeRecognition, PsychologyVisual PerceptionYoung AdultConceptsFunctional magnetic resonance imagingAlcohol use disorderBOLD responseBilateral posterior parietal cortexMemory task performanceHeavy-drinking college studentsInferior frontal activationRight dorsolateral prefrontalCorrect encodingWorse memory performanceDefault mode regionsIncorrect encodingAlcohol-related impairmentMemory-related areasHeavy drinkersGreater BOLD responseLight drinkersPosterior parietal cortexBlood oxygen level-dependent functional magnetic resonance imagingQuantity/frequencyLevel-dependent functional magnetic resonance imagingInsula responseNeural correlatesFigural memoryFrontal activation