2024
Development and Testing of a Mobile App for Management of Gestational Diabetes in Nepal: Protocol for a User-Centered Design Study and Exploratory Randomized Controlled Trial
Berube L, Shrestha A, Shrestha A, Daneault J, Shakya P, Dhimal M, Shrestha R, Rawal S. Development and Testing of a Mobile App for Management of Gestational Diabetes in Nepal: Protocol for a User-Centered Design Study and Exploratory Randomized Controlled Trial. JMIR Research Protocols 2024, 13: e59423. PMID: 39432898, PMCID: PMC11535795, DOI: 10.2196/59423.Peer-Reviewed Original ResearchMultilevel determinants of antiretroviral therapy initiation and retention in the test-and-treat era of Nepal: a qualitative study
Shrestha A, Poudel L, Shrestha S, Jha N, Kuikel B, Shakya P, Kunwar R, Pandey L, KC M, Wilson E, Deuba K. Multilevel determinants of antiretroviral therapy initiation and retention in the test-and-treat era of Nepal: a qualitative study. BMC Health Services Research 2024, 24: 927. PMID: 39138448, PMCID: PMC11323673, DOI: 10.1186/s12913-024-11311-6.Peer-Reviewed Original ResearchConceptsAntiretroviral therapy initiationHealthcare providersDenial of HIV statusPerspectives of healthcare providersAntiretroviral therapyCommunity health workersStrengthening healthcare systemsART initiationHealth system levelLong-term health outcomesHealthcare system levelAntiretroviral therapy clientsChanging public health policyFear of disclosureIndividual-level facilitatorsSocio-ecological modelImplementing antiretroviral therapyAvailability of medicationsPublic health policiesAntiretroviral therapy adherencePerceived health benefitsFear of deathClient tracking systemProvision of free treatmentHealth workersImpact of a community health worker led intervention for improved blood pressure control in urban Nepal: an open-label cluster randomised controlled trial
Bhattarai S, Skovlund E, Shrestha A, Mjølstad B, Åsvold B, Sen A. Impact of a community health worker led intervention for improved blood pressure control in urban Nepal: an open-label cluster randomised controlled trial. The Lancet Regional Health - Southeast Asia 2024, 29: 100461. PMID: 39220804, PMCID: PMC11364134, DOI: 10.1016/j.lansea.2024.100461.Peer-Reviewed Original ResearchCommunity health workersIntervention arm compared to controlsWaist-to-hip ratioHealth workersRandomised controlled trialsBody mass indexPhysical activityDaily salt intakeHealthcare providersSystolic blood pressureDiastolic blood pressureCluster randomised controlled trialOpen-label cluster randomised controlled trialRoutine follow-up careMass indexHealth system barriersAdequate physical activityControlled trialsTrained healthcare providersDiet quality scoresBlood pressure controlPublic health facilitiesInterventions targeting individualsUrban NepalControl blood pressureExploring ways to support patients with noncommunicable diseases: A pilot study in Nepal during the COVID-19 pandemic
Iwashita H, Shrestha R, Yadav U, Shrestha A, Makaju D, Harada Y, Masuda G, Rawal L, Shrestha A, Karmacharya B, Koju R, Sakamoto H, Sugishita T. Exploring ways to support patients with noncommunicable diseases: A pilot study in Nepal during the COVID-19 pandemic. PLOS Global Public Health 2024, 4: e0003509. PMID: 39028727, PMCID: PMC11259295, DOI: 10.1371/journal.pgph.0003509.Peer-Reviewed Original ResearchNon-communicable diseasesQualitative interviewsDevelopment of non-communicable diseasesImprove health literacyCommunity-based awareness programContinuity of careNuwakot district of NepalLack of transportationCommunity-based programsImplementing telemedicine servicesFear of infectionCOVID-19 pandemicHealth literacyLow-income countriesHealthcare useHealthy behaviorsHealthcare providersHealthcare servicesNoncommunicable diseasesPotential facilitatorsHealthcare systemTelemedicine servicesMedical careTelephone surveyDistrict of NepalEffect of a Mobile Health Intervention on Self-Monitoring and Management of Glucose and Blood Pressure Among Women With Gestational Diabetes
Shanmugavel A, Shrestha A, Daneault J, Shakya P, Nepal J, Chaudhary K, Shrestha A, Rawal S. Effect of a Mobile Health Intervention on Self-Monitoring and Management of Glucose and Blood Pressure Among Women With Gestational Diabetes. Current Developments In Nutrition 2024, 8: 103116. DOI: 10.1016/j.cdnut.2024.103116.Peer-Reviewed Original ResearchEffects of a dietary intervention on cardiometabolic risk and food consumption in a workplace
Shrestha A, Tamrakar D, Ghinanju B, Shrestha D, Khadka P, Adhikari B, Shrestha J, Waiwa S, Pyakurel P, Bhandari N, Karmacharya B, Shrestha A, Shrestha R, Bhatta R, Malik V, Mattei J, Spiegelman D. Effects of a dietary intervention on cardiometabolic risk and food consumption in a workplace. PLOS ONE 2024, 19: e0301826. PMID: 38656951, PMCID: PMC11042715, DOI: 10.1371/journal.pone.0301826.Peer-Reviewed Original ResearchConceptsConsumption of whole grainsHealthy foodPre-post intervention studyWhole grainsMedian consumptionCardiovascular risk factor profileRisk factor profileBlood pressureWorksite settingWorksite interventionsUnhealthy foodsHealth programsMeasured blood pressurePre-hypertensionCardiometabolic riskDiastolic blood pressureIntervention studiesFactors dietPaired-t testFactor profileFasting glucose levelsDhulikhel HospitalHospital premisesEmployee healthHospital employeesBarriers and Facilitators of Implementing a Healthy Lifestyle Intervention at Workplaces in South Africa
Singh S, Naicker A, Grobbelaar H, Singh E, Spiegelman D, Shrestha A. Barriers and Facilitators of Implementing a Healthy Lifestyle Intervention at Workplaces in South Africa. International Journal Of Environmental Research And Public Health 2024, 21: 389. PMID: 38673303, PMCID: PMC11050208, DOI: 10.3390/ijerph21040389.Peer-Reviewed Original ResearchFocus group discussionsHealthy lifestyle interventionIn-depth interviewsLifestyle interventionIntervention programmeDesigning lifestyle interventionsImplement lifestyle interventionsCardiovascular risk factor profileLifestyle intervention programmeImprove health outcomesImplementing health programmesLack of willpowerSemi-structured in-depth interviewsRisk factor profileImplementing intervention programmesFood environmentHealth outcomesImplement interventionsHealth programmesWorkplace stakeholdersWellness programmesWorkplace supportLifestyle choicesFactor profileGroup discussionsDigital health interventions for suicide prevention among LGBTQ: A narrative review
Paudel K, Gautam K, Bhandari P, Shah S, Wickersham J, Acharya B, Sapkota S, Adhikari S, Baral P, Shrestha A, Shrestha R. Digital health interventions for suicide prevention among LGBTQ: A narrative review. Health Prospect 2024, 23: 1-10. PMID: 38645301, PMCID: PMC11027749, DOI: 10.3126/hprospect.v23i1.62795.Peer-Reviewed Original ResearchDigital health interventionsMcGill Mixed Methods Appraisal ToolRandomized controlled trialsDigital interventionsHealth interventionsSuicide preventionHealth servicesQualitative studyMixed Methods Appraisal ToolIncrease help-seeking behaviorImpact of digital interventionsConventional health servicesMethods Appraisal ToolHelp-seeking intentionsObtaining such servicesPre-posttest designHelp-seeking behaviorSuicidal thoughtsMiddle-income countriesDigital-based interventionsProportion of participantsPowered randomized controlled trialsNon-overlapping studiesLGBTQ communityPerceived stigmaChallenges in Effective Referral of Cardiovascular Diseases in Nepal: A Qualitative Study from Health Workers’ and Patients’ Perspective
Shrestha S, Maharjan R, Bajracharya S, Jha N, Mali S, Thapa B, Suwal P, Prajapati D, Karmacharya B, Shrestha A. Challenges in Effective Referral of Cardiovascular Diseases in Nepal: A Qualitative Study from Health Workers’ and Patients’ Perspective. Cardiology Research And Practice 2024, 2024: 5583709. PMID: 38476339, PMCID: PMC10932621, DOI: 10.1155/2024/5583709.Peer-Reviewed Original ResearchReferral systemCardiovascular disease patientsCVD casesNoncommunicable diseasesCardiovascular diseaseQualitative studyBurden of noncommunicable diseasesCardiovascular disease careFactors affecting referralTertiary-level careCardiovascular disease casesOpen-ended questionsTranscribed verbatimHealth workersLack of human resourcesHealthcare professionalsPatient perspectiveFace-to-faceEffective referralInterview guideMadhesh ProvinceThematic approachTelephone interviewsPatient transferReferral strategiesCyberbullying and cyber-victimisation among higher secondary school adolescents in an urban city of Nepal: a cross-sectional study
Kunwar S, Sharma S, Marasini S, Joshi A, Adhikari A, Ranjit A, Shrestha I, Shrestha A, Shrestha A, Karmacharya B. Cyberbullying and cyber-victimisation among higher secondary school adolescents in an urban city of Nepal: a cross-sectional study. BMJ Open 2024, 14: e081016. PMID: 38448066, PMCID: PMC10916119, DOI: 10.1136/bmjopen-2023-081016.Peer-Reviewed Original ResearchConceptsPokhara Metropolitan CityMultivariate logistic regression analysisCyber-victimisationSchool adolescentsPrevalence of cyberbullyingLogistic regression analysisCross-sectional studyHealth-related consequencesSecondary school adolescentsPost meanFactors associated with cyberbullyingHigh school adolescentsPeriodic screeningCounseling servicesEducation programmesHurtful commentsOnline Aggression SurveyPrevalenceConsequences of cyberbullyingCity of NepalAssociated with cyberbullyingMetropolitan citiesAnti-bullying policiesRegression analysisRole of Perceived Social Support in Adherence to Antihypertensives and Controlled Hypertension: Findings of a Community Survey from Urban Nepal
Bhattarai S, Wagle D, Shrestha A, Åsvold B, Skovlund E, Sen A. Role of Perceived Social Support in Adherence to Antihypertensives and Controlled Hypertension: Findings of a Community Survey from Urban Nepal. Patient Preference And Adherence 2024, 18: 767-777. PMID: 38558834, PMCID: PMC10981373, DOI: 10.2147/ppa.s455511.Peer-Reviewed Original ResearchHigh social supportSocial supportEffective management of chronic conditionsImplementing community-based interventionsImprove adherence to antihypertensive medicationsControlled hypertensionHypertension managementMultidimensional Scale of Perceived Social SupportScale of Perceived Social SupportManagement of chronic conditionsModified Poisson regression modelsAdherence to antihypertensive medicationsMorisky Medication Adherence Scale-8Proportion of controlled hypertensionCommunity-based interventionsMeasure social supportAnalyzed cross-sectional dataUrban NepalCluster randomized trialPerceived social supportPoisson regression modelsControl of hypertensionSocial support categoriesCross-sectional dataChronic conditionsExploring knowledge, perceptions, and practices of antimicrobials, and their resistance among medicine dispensers and community members in Kavrepalanchok District of Nepal
Marasini S, Sharma S, Joshi A, Kunwar S, Mahato R, Shrestha A, Karmacharya B. Exploring knowledge, perceptions, and practices of antimicrobials, and their resistance among medicine dispensers and community members in Kavrepalanchok District of Nepal. PLOS ONE 2024, 19: e0297282. PMID: 38241275, PMCID: PMC10798439, DOI: 10.1371/journal.pone.0297282.Peer-Reviewed Original ResearchConceptsFocus group discussionsIn-depth interviewsMedicine dispensingCommunity membersGroup discussionsSelf-medicationGlobal public health issuePublic health issueOver-the-counter salesInappropriate use of antimicrobialsThematic analysisDispensing practicesHealth issuesOver-the-counterInductive approachInappropriate useWeak enforcement of policiesDrug useUrban municipalitiesEducational backgroundAntimicrobial resistanceDispensingConsumers express concernsIn-depthPharmacyDesigning and Developing a Mobile App for Management and Treatment of Gestational Diabetes in Nepal: User-Centered Design Study.
Shanmugavel A, Shakya P, Shrestha A, Nepal J, Shrestha A, Daneault J, Rawal S. Designing and Developing a Mobile App for Management and Treatment of Gestational Diabetes in Nepal: User-Centered Design Study. JMIR Formative Research 2024, 8: e50823. PMID: 38231562, PMCID: PMC10831589, DOI: 10.2196/50823.Peer-Reviewed Original Research
2023
Effectiveness of a group-based Diabetes Prevention Education Program (DiPEP) in a population with pre-diabetes: a cluster randomised controlled trial in Nepal
Shakya P, Shrestha A, Bajracharya M, Shrestha A, Kulseng B, Karmacharya B, Shrestha S, Das S, Shrestha I, Barun K, Shrestha N, Skovlund E, Sen A. Effectiveness of a group-based Diabetes Prevention Education Program (DiPEP) in a population with pre-diabetes: a cluster randomised controlled trial in Nepal. BMJ Nutrition Prevention & Health 2023, 6: 253-263. PMID: 38264365, PMCID: PMC10800278, DOI: 10.1136/bmjnph-2023-000702.Peer-Reviewed Original ResearchDiabetes prevention education programControl armIntervention armEducational sessionsMean differencePrevention education programPostintervention assessmentsLifestyle intervention programLifestyle intervention studyTRIAL REGISTRATION NUMBERTwo-arm clusterSecondary outcomesDiabetes preventionMiddle-income countriesPrimary outcomeTreat analysisWaist circumferenceMonths interventionPhysical activityRegistration numberGrain intakeIntervention studiesBaseline measuresSignificant weight reductionIntervention programsFacilitators and barriers to hypertension management in urban Nepal: findings from a qualitative study
Bhattarai S, Bajracharya S, Shrestha A, Skovlund E, Åsvold B, Mjolstad B, Sen A. Facilitators and barriers to hypertension management in urban Nepal: findings from a qualitative study. Open Heart 2023, 10: e002394. PMID: 37899127, PMCID: PMC10618998, DOI: 10.1136/openhrt-2023-002394.Peer-Reviewed Original ResearchConceptsPrimary healthcare providersHypertension servicesHypertension managementHealthcare providersHypertension patientsHome visitsSocioecological modelCommunity-level barriersUrban NepalFocus group discussionsTreatment measuresControl of hypertensionGender normsHigh blood pressureCommunity health workersMunicipal officialsAspects of careFamily membersDepth interviewsQualitative methodologyPrimary healthcare systemCommunity trustLow-resource countriesQualitative studyAntihypertensive medicationsSolyx Minisling Surgery for Stress Urinary Incontinence: Dhulikhel Hospital Initiative.
Shrestha A, Hagemeier T. Solyx Minisling Surgery for Stress Urinary Incontinence: Dhulikhel Hospital Initiative. Kathmandu University Medical Journal 2023, 21: 227-229. PMID: 38628019.Peer-Reviewed Original ResearchConceptsStress urinary incontinenceLeakage of urineUrinary incontinenceTreat stress urinary incontinenceInvoluntary leakage of urineSingle-incision proceduresWeeks of surgeryMinimally invasive procedureMini slingSling surgeryVaginal incisionMini-slingInvoluntary leakageSolyxInvasive proceduresSurgeryEffective treatmentSlingAdult womenIncisionSuccess rateHospital InitiativeMedical conditionsIncontinenceWomen
2022
Analyzing the Implementation of Policies and Guidelines for the Prevention and Management of Type 2 Diabetes at Primary Health Care Level in Nepal
Shrestha R, Yadav UN, Shrestha A, Paudel G, Makaju D, Poudel P, Iwashita H, Harada Y, Shrestha A, Karmacharya B, Koju R, Sugishita T, Rawal L. Analyzing the Implementation of Policies and Guidelines for the Prevention and Management of Type 2 Diabetes at Primary Health Care Level in Nepal. Frontiers In Public Health 2022, 10: 763784. PMID: 35223722, PMCID: PMC8864089, DOI: 10.3389/fpubh.2022.763784.Peer-Reviewed Original ResearchConceptsPrimary health care levelHealth care levelNon-communicable diseasesHealth care providersCare levelDiabetes preventionCare providersPhase IManagement of NCDsDiabetes care servicesType 2 diabetesPeripheral health servicesProblem of diabetesKey search termsKey informant interviewsDiabetes carePeripheral levelsRelevant grey literatureType 2Care servicesDiabetesHealth servicesPremature deathPreventionQualitative exploratory study
2021
Diabetes Prevention Education Program in a population with pre-diabetes in Nepal: a study protocol of a cluster randomised controlled trial (DiPEP)
Shakya P, Shrestha A, Karmacharya BM, Shrestha A, Kulseng BE, Skovlund E, Sen A. Diabetes Prevention Education Program in a population with pre-diabetes in Nepal: a study protocol of a cluster randomised controlled trial (DiPEP). BMJ Open 2021, 11: e047067. PMID: 34819277, PMCID: PMC8614149, DOI: 10.1136/bmjopen-2020-047067.Peer-Reviewed Original ResearchConceptsDiabetes prevention education programIntervention armPrevention education programControl armRandom blood sugar valuesIndian Diabetes Risk ScoreNepal Health Research CouncilLifestyle intervention programDiabetes Risk ScoreBlood sugar valuesInstitutional Review CommitteeHealth Research CouncilKathmandu University SchoolWorkers/volunteersHealth Research EthicsDiabetes burdenStudy protocolHealthcare workersTwo-armHigh-income countriesOutcome measuresPhysical activityRisk scoreHealth literacyQualitative studyA Rare Case of Large Left Lateral Wall Vaginal Myoma
Shrestha A, Mudbari J, Tamrakar S, Pradhan N, Makaju R, Karki S. A Rare Case of Large Left Lateral Wall Vaginal Myoma. Kathmandu University Medical Journal 2021, 19: 396-398. PMID: 36254433, DOI: 10.3126/kumj.v19i3.49748.Peer-Reviewed Original ResearchConceptsMagnetic resonance imagingVaginal wallClinical findingsLeft vaginal wallChronic pelvic painSmooth muscle tumorsVariable clinical presentationBulky uterusVaginal myomaVaginal myomectomyPelvic painMuscle tumorsVaginal leiomyomaGuided biopsyBenign tumorsClinical presentationPressure symptomsYears ladyMass lesionRare caseLeiomyomaCervixUltrasonographyResonance imagingVaginumSocioeconomic Status and Its Relation to Hypertension in Rural Nepal
Bhattarai S, Tandstad B, Shrestha A, Karmacharya B, Sen A. Socioeconomic Status and Its Relation to Hypertension in Rural Nepal. International Journal Of Hypertension 2021, 2021: 5542438. PMID: 34497724, PMCID: PMC8419497, DOI: 10.1155/2021/5542438.Peer-Reviewed Original ResearchLifestyle factorsBlood pressureMiddle-income countriesPrevalence ratiosSocioeconomic positionBlood pressure-lowering medicinesAge-standardized prevalenceSocioeconomic statusDiastolic blood pressureSystolic blood pressureRural health centersCross-sectional studySocioeconomic factorsRural NepalPoisson regression modelsHypertension prevalenceHypertensive participantsHealth centersHypertensionStudy participantsCausal mediation analysisConfidence intervalsSelf-reported dataEvidence of mediationFurther studies