Jennifer Frampton, DO, MPH
Assistant Professor of Medicine (Cardiovascular Medicine)Cards
About
Research
Publications
2024
Complete revascularization versus culprit‐only revascularization in older adults with ST‐elevation myocardial infarction: Systematic review and meta‐analysis of randomized controlled trials
Park D, Hu J, Frampton J, Rymer J, Al Damluji A, Nanna M. Complete revascularization versus culprit‐only revascularization in older adults with ST‐elevation myocardial infarction: Systematic review and meta‐analysis of randomized controlled trials. Journal Of The American Geriatrics Society 2024 PMID: 39639558, DOI: 10.1111/jgs.19295.Peer-Reviewed Original ResearchContrast-associated acute kidney injuryST-elevation myocardial infarctionCulprit-only revascularizationRandomized controlled trialsComplete revascularizationHazard of MACEMeta-analysisOlder adultsHazard ratioClass III to class IMeta-analysis of randomized controlled trialsAssociated with reduced MACEMyocardial infarctionControlled trialsAcute kidney injuryRandomized controlled trials of CRAdverse cardiovascular eventsBenefits of CRComplexity of lesionsRandom-effects modelBleeding riskKidney injuryMeta-analysis to dateCardiovascular eventsSubgroup analysisHeartbeats and bank statements: a survey of the financial pulse of cardiologists.
Simsek B, Rangan B, Ahmad Y, Azzalini L, Davies R, Frampton J, Khatri J, Kirtane A, Lansky A, Lombardi W, Sandoval Y, Sauer A, Wilson J, Brilakis E. Heartbeats and bank statements: a survey of the financial pulse of cardiologists. Journal Of Invasive Cardiology 2024 PMID: 39453869, DOI: 10.25270/jic/24.00292.Peer-Reviewed Original ResearchTrend of Controlled Low-Density Lipoprotein Cholesterol in Older Adults With a History of Myocardial Infarction or Stroke
Park D, Jamil Y, Frampton J, Al Damluji A, Nanna M. Trend of Controlled Low-Density Lipoprotein Cholesterol in Older Adults With a History of Myocardial Infarction or Stroke. JACC Advances 2024, 3: 101091. PMID: 39099776, PMCID: PMC11294686, DOI: 10.1016/j.jacadv.2024.101091.Peer-Reviewed Original ResearchRepresentation of Older Adults in the ACC/AHA/SCAI Guideline for Coronary Artery Revascularization
Jamil Y, Sibindi C, Park D, Frampton J, Damluji A, Nanna M. Representation of Older Adults in the ACC/AHA/SCAI Guideline for Coronary Artery Revascularization. JAMA Network Open 2024, 7: e2421547. PMID: 38995647, PMCID: PMC11245718, DOI: 10.1001/jamanetworkopen.2024.21547.Peer-Reviewed Original ResearchAssociation of cardiovascular diseases with cognitive performance in older adults
Park D, Jamil Y, Babapour G, Kim J, Campbell G, Akman Z, Kochar A, Sen S, Samsky M, Sikand N, Frampton J, Damluji A, Nanna M. Association of cardiovascular diseases with cognitive performance in older adults. American Heart Journal 2024, 273: 10-20. PMID: 38575050, PMCID: PMC11162917, DOI: 10.1016/j.ahj.2024.03.016.Peer-Reviewed Original ResearchAnimal Fluency TestOlder adultsCERAD-DRDSST scoresCardiovascular diseaseNational Health and Nutrition Examination SurveyHealth and Nutrition Examination SurveyCongestive heart failureFree of cardiovascular diseaseFluency testCardiovascular disease subtypesNutrition Examination SurveyAssociation of cardiovascular diseaseAnimal Fluency test scoreCognitive performanceLower cognitive performanceCoronary heart diseaseHeart failureCVD subtypesExamination SurveyAssess cognitive performanceAdultsCognitive functionHeart diseaseScoresREPRESENTATION OF OLDER ADULTS IN THE CURRENT ACC/AHA/SCAI GUIDELINE FOR CORONARY ARTERY REVASCULARIZATION
Jamil Y, Sibindi C, Park D, Frampton J, Damluji A, Nanna M. REPRESENTATION OF OLDER ADULTS IN THE CURRENT ACC/AHA/SCAI GUIDELINE FOR CORONARY ARTERY REVASCULARIZATION. Journal Of The American College Of Cardiology 2024, 83: 852. DOI: 10.1016/s0735-1097(24)02842-0.Peer-Reviewed Original ResearchShorter Dual Antiplatelet Therapy for Older Adults After Percutaneous Coronary Intervention
Park D, Hu J, Jamil Y, Kelsey M, Jones W, Frampton J, Kochar A, Aronow W, Damluji A, Nanna M. Shorter Dual Antiplatelet Therapy for Older Adults After Percutaneous Coronary Intervention. JAMA Network Open 2024, 7: e244000. PMID: 38546647, PMCID: PMC10979312, DOI: 10.1001/jamanetworkopen.2024.4000.Peer-Reviewed Original ResearchConceptsOlder adultsMonths of DAPTDuration of dual antiplatelet therapySystematic reviewRandomized clinical trialsPercutaneous coronary interventionMeta-analysisPreferred Reporting ItemsAssess data qualityRisk of bleedingDuration of DAPTDual antiplatelet therapyWeb of ScienceMain OutcomesReporting ItemsData extractionAbstracted dataSecondary outcomesRisk ratioAntiplatelet therapyPrimary outcomeCochrane LibraryCoronary interventionReference groupNetwork meta-analysis
2023
Do Clinical Outcomes and Quality of Life Differ by the Number of Antianginals for Stable Ischemic Heart Disease? Insights from the BARI 2D Trial
Jamil Y, Park D, Verde L, Sherwood M, Tehrani B, Batchelor W, Frampton J, Damluji A, Nanna M. Do Clinical Outcomes and Quality of Life Differ by the Number of Antianginals for Stable Ischemic Heart Disease? Insights from the BARI 2D Trial. The American Journal Of Cardiology 2023, 214: 66-76. PMID: 38160927, PMCID: PMC10923116, DOI: 10.1016/j.amjcard.2023.12.045.Peer-Reviewed Original ResearchStable ischemic heart diseaseAnti-anginal agentIntensive medical therapyIschemic heart diseaseMedical therapyQOL metricsHeart diseaseFindings merit further researchMajor adverse cardiovascular eventsAnti-anginal treatmentBARI 2D trialGreater QoL improvementAdverse cardiovascular eventsMyocardial jeopardy indexCardiovascular eventsCause mortalityCardiovascular endpointsClinical confoundersPatient characteristicsDiabetes mellitusHeart failureTherapy intensityClinical outcomesQOL improvementMyocardial infarctionThe association of timing of coronary artery bypass grafting for non-ST-elevation myocardial infarction and clinical outcomes in the contemporary United States
Park D, Singireddy S, Mangalesh S, Fishman E, Ambrosini A, Jamil Y, Vij A, Sikand N, Ahmad Y, Frampton J, Nanna M. The association of timing of coronary artery bypass grafting for non-ST-elevation myocardial infarction and clinical outcomes in the contemporary United States. Coronary Artery Disease 2023, 35: 261-269. PMID: 38164979, PMCID: PMC11042982, DOI: 10.1097/mca.0000000000001314.Peer-Reviewed Original ResearchLength of stayCoronary artery bypassElevation myocardial infarctionNSTEMI hospitalizationsHospital mortalityArtery bypassCABG surgeryMyocardial infarctionHigher oddsLonger LOSBurden of complicationsHospital-associated costsNon-home dischargeAcute kidney injuryHigh-risk featuresPercutaneous coronary interventionAssociation of timingOutcomes of interestNSTEMI populationGastrointestinal hemorrhageHospital outcomesKidney injuryPerioperative complicationsCoronary interventionBlood transfusionCoronary Intravascular Lithotripsy for Treatment of Severely Calcified Lesions: Long-Term Sex-Specific Outcomes
Frampton J, Kearney K, Abbott J, Kereiakes D, Di Mario C, Saito S, Cristea E, Riley R, Fajadet J, Shlofmitz R, Ali Z, Klein A, Price M, Hill J, Stone G, Lansky A. Coronary Intravascular Lithotripsy for Treatment of Severely Calcified Lesions: Long-Term Sex-Specific Outcomes. Journal Of The Society For Cardiovascular Angiography & Interventions 2023, 2: 101069. PMID: 39129889, PMCID: PMC11307843, DOI: 10.1016/j.jscai.2023.101069.Peer-Reviewed Original ResearchIntravascular lithotripsyLesion failureIschemia-driven target lesion revascularizationMajor adverse cardiac event ratesAdverse cardiac event ratesDrug-eluting stent placementMajor adverse cardiac eventsSmaller reference vessel diameterTarget vessel myocardial infarctionCoronary intravascular lithotripsyAdverse cardiac eventsCardiac event ratePrimary end pointTarget lesion failureTarget lesion revascularizationVessel myocardial infarctionReference vessel diameterAdverse clinical eventsHigh procedural successSex-based outcomesSex-specific outcomesLesion revascularizationAngiographic outcomesCardiac eventsCardiac death
Clinical Care
Jennifer Frampton, DO, MPH, is an interventional cardiologist, practicing a subspecialty that uses specialized imaging techniques and catheter-based treatments to treat the heart and blood vessels. Dr. Frampton provides coronary angiography and percutaneous coronary interventions, specifically focusing on complex coronary artery disease and chronic total occlusions (CTO).
Overview
Jennifer Frampton, DO, MPH, is an interventional cardiologist, practicing a subspecialty that uses specialized imaging techniques and nonsurgical catheter-based treatments to treat the heart and blood vessels. Dr. Frampton provides coronary angiography and percutaneous coronary interventions, in addition to consultative cardiology care for new patients and follow-up visits to monitor their progress after treatment.
Dr. Frampton says she was drawn to interventional cardiology when she saw that it was an opportunity to help people manage cardiac conditions with both medicines and procedures.
“My goal is to provide patient-centered care with attention to the needs and preferences of each individual patient,” Dr. Frampton says. This often means helping patients through the trajectory of their disease, starting with initial diagnosis and treatment, and continuing through long-term management of the condition. “I strive to work with each patient on disease management, with a focus on longevity and maintaining a healthy and active lifestyle,” she says.
Clinical Specialties
Fact Sheets
Percutaneous Coronary Intervention (PCI)
Learn More on Yale MedicineCoronary Artery Disease (CAD)
Learn More on Yale MedicineChronic Total Occlusion (CTO)
Learn More on Yale MedicineCoronary Atherosclerosis Treatments
Learn More on Yale Medicine
Board Certifications
Interventional Cardiology
- Certification Organization
- AB of Internal Medicine
- Original Certification Date
- 2021
Adult Comprehensive Echocardiography
- Certification Organization
- National Board of Echocardiography
- Original Certification Date
- 2020
Cardiovascular Disease
- Certification Organization
- AB of Internal Medicine
- Original Certification Date
- 2020
Internal Medicine
- Certification Organization
- AB of Internal Medicine
- Original Certification Date
- 2017
Yale Medicine News
News
News
- May 01, 2024
Yale Department of Internal Medicine Faculty Promotions and Appointments (May 2024)
- April 01, 2024
Yale Faculty Present Groundbreaking Clinical Research at the 2024 American College of Cardiology Scientific Sessions
- February 01, 2023
2023 American College of Cardiology late-breaking clinical trials and abstracts from Yale
- October 06, 2022
Most-read Content of September: Using risk scores to improve patient outcomes, dual antiplatelet therapy, and more