2006
In vitro assessment of dendritic cells pulsed with apoptotic tumor cells as a vaccine for ovarian cancer patients
Tobiásová Z, Pospíšilová D, Miller A, Minárik I, Sochorová K, Špíšek R, Rob L, Bartůňková J. In vitro assessment of dendritic cells pulsed with apoptotic tumor cells as a vaccine for ovarian cancer patients. Clinical Immunology 2006, 122: 18-27. PMID: 17059893, DOI: 10.1016/j.clim.2006.09.003.Peer-Reviewed Original ResearchConceptsOvarian cancer patientsCancer patientsDendritic cellsAutologous irradiated tumor cellsLymphocyte IFN-gamma productionTumor cellsAntigen-pulsed DCsIFN-gamma ELISPOTMonocyte-derived DCsMaturation of DCsIrradiated tumor cellsIFN-gamma productionNew treatment optionsAbility of DCsResidual tumour diseaseProliferation of lymphocytesApoptotic tumor cellsTumor cell apoptosisDC vaccinesAutologous lymphocytesLymphocyte responsesStandard treatmentTreatment optionsOvarian cancerPatients
2004
Immunotherapy--perspectives in therapy of ovarian carcinomas.
Zapletalová K, Tobiasová Z, Spísek R, Rob L, Bartůnková J. Immunotherapy--perspectives in therapy of ovarian carcinomas. Česká Gynekologie 2004, 69: 372-5. PMID: 15587893.Peer-Reviewed Original ResearchMeSH KeywordsAntibodies, MonoclonalCancer VaccinesCombined Modality TherapyCytokinesFemaleHumansImmunotherapyOvarian NeoplasmsConceptsUniversity Hospital MotolMonoclonal antibody therapyCytokine therapyAntibody therapyMalignant ovarian epithelial tumorsCombination of surgeryDepartment of GynecologyOvarian cancer patientsOvarian epithelial tumorsDendritic cellsVaccine therapyMedical FacultyCancer patientsIL-2Clinical studiesTherapeutic protocolsEpithelial tumorsTherapyGM-CSFImmunotherapyTumor cellsMotolChemotherapySurgeryUsual standard