In vitro assessment of dendritic cells pulsed with apoptotic tumor cells as a vaccine for ovarian cancer patients
Tobiásová Z, Pospíšilová D, Miller A, Minárik I, Sochorová K, Špíšek R, Rob L, Bartůňková J. In vitro assessment of dendritic cells pulsed with apoptotic tumor cells as a vaccine for ovarian cancer patients. Clinical Immunology 2006, 122: 18-27. PMID: 17059893, DOI: 10.1016/j.clim.2006.09.003.Peer-Reviewed Original ResearchConceptsOvarian cancer patientsCancer patientsDendritic cellsAutologous irradiated tumor cellsLymphocyte IFN-gamma productionTumor cellsAntigen-pulsed DCsIFN-gamma ELISPOTMonocyte-derived DCsMaturation of DCsIrradiated tumor cellsIFN-gamma productionNew treatment optionsAbility of DCsResidual tumour diseaseProliferation of lymphocytesApoptotic tumor cellsTumor cell apoptosisDC vaccinesAutologous lymphocytesLymphocyte responsesStandard treatmentTreatment optionsOvarian cancerPatients