Cell-Free Fat Extract with Anti-melanogenic Property Improves the Appearance of Infraorbital Dark Circles: A Preliminary Clinical Study
Kang B, Cai Y, Jia Z, Yao L, Gu J, Li W, Zhang W. Cell-Free Fat Extract with Anti-melanogenic Property Improves the Appearance of Infraorbital Dark Circles: A Preliminary Clinical Study. Aesthetic Plastic Surgery 2024, 1-10. PMID: 39532743, DOI: 10.1007/s00266-024-04445-9.Peer-Reviewed Original ResearchCell-free fat extractInfraorbital dark circlesDark circlesFollow-upLevel of Evidence IVThis journalEvidence-Based Medicine ratingsPreliminary clinical studiesLevel of evidenceStatistically significant improvementIVThis journalClinical studiesIntradermal injectionClinical trialsPeriocular wrinklesClinical trial assessmentEvaluation of skin colorEffective treatmentMelanin contentConclusionOur studyPatientsTreatmentInhibited melanin synthesisOnline InstructionsZebrafish embryosSignificant improvement