2018
Novel Eye Plaque Designs for Brachytherapy of Iris and Ciliary Body Melanoma and the First Clinical Application
Liu W, Kim JM, Young BK, Nath R, Chen Z, Decker RH, Astrahan MA, Pointdujour-Lim R. Novel Eye Plaque Designs for Brachytherapy of Iris and Ciliary Body Melanoma and the First Clinical Application. Ocular Oncology And Pathology 2018, 5: 220-228. PMID: 31049331, PMCID: PMC6489066, DOI: 10.1159/000493269.Peer-Reviewed Original ResearchIris melanomaCiliary bodyFirst clinical applicationPlaque designPoor patient tolerabilityCiliary body melanomaClinical applicationEye plaque brachytherapyPatient tolerabilityAdverse eventsCorneal edemaPlaque brachytherapyTumor apexTumor baseClinical casesMelanomaPatientsPlaquesSurgical maneuverabilityPlaque modelEffective dose distributionTreatment planningTolerabilityTreatmentImage-based treatment planning
2017
Incorporating patient-specific CT-based ophthalmic anatomy in modeling iodine-125 eye plaque brachytherapy dose distributions
Tien CJ, Astrahan MA, Kim JM, Materin M, Chen Z, Nath R, Liu W. Incorporating patient-specific CT-based ophthalmic anatomy in modeling iodine-125 eye plaque brachytherapy dose distributions. Brachytherapy 2017, 16: 1057-1064. PMID: 28778599, DOI: 10.1016/j.brachy.2017.06.014.Peer-Reviewed Original ResearchConceptsEye modelDisc distanceDose differenceTumor apexPrescription doseOcular parametersPlaque SimulatorOcular structuresSubstantial dose differencesTarget volumePlaque positionDosimetric parametersPatientsClinical planningDosimetric impactSignificant differencesBrachytherapy planningSeed strengthPlaquesBrachytherapy dose distributionsDose distributionPatient-specific modelsDifferencesTumorsRetina