2010
Intraflagellar Transport Proteins Are Essential for Cilia Formation and for Planar Cell Polarity
Cao Y, Park A, Sun Z. Intraflagellar Transport Proteins Are Essential for Cilia Formation and for Planar Cell Polarity. Journal Of The American Society Of Nephrology 2010, 21: 1326-1333. PMID: 20576807, PMCID: PMC2938599, DOI: 10.1681/asn.2009091001.Peer-Reviewed Original ResearchConceptsPlanar cell polarityIntraflagellar transport proteinsCell polarityCilia formationIFT mutantsIFT proteinsDefective planar cell polarityTransport proteinsCore PCP componentsKidney cyst formationConserved roleEarly developmental stagesCiliary assemblyIFT genesPCP componentsCilia formMulticiliated cellsPronephric ductGene productsMaternal contributionBasal bodiesMultiple organismsDevelopmental stagesMaternal depositionProtein
2009
Cilia localization is essential for in vivo functions of the Joubert syndrome protein Arl13b/Scorpion
Duldulao NA, Lee S, Sun Z. Cilia localization is essential for in vivo functions of the Joubert syndrome protein Arl13b/Scorpion. Development 2009, 136: 4033-4042. PMID: 19906870, PMCID: PMC2778746, DOI: 10.1242/dev.036350.Peer-Reviewed Original ResearchConceptsCilia formationVivo functionJoubert syndromeSeries of deletionsSonic hedgehog (Shh) signalingCilia localizationCiliary localizationNull mutantsPoint mutantsGene productsHedgehog signalingArl13bCiliary defectsMutantsKidney ductsZebrafishCiliaAutosomal recessive disorderAbnormal ultrastructureScorpionsRecessive disorderLocalizationRecent studiesKnockdownSignaling