1996
Cocaine-abusing Parturients Undergoing Cesarean Section
Kain Z, Mayes L, Ferris C, Pakes J, Schottenfeld R. Cocaine-abusing Parturients Undergoing Cesarean Section. Anesthesiology 1996, 85: 1028-1035. PMID: 8916819, DOI: 10.1097/00000542-199611000-00010.Peer-Reviewed Original ResearchConceptsCocaine-abusing parturientsCesarean section deliverySection deliveryCesarean sectionCocaine useOperative blood lossDiastolic blood pressureDiastolic hypertensionPeripartum eventsAbruptio placentaeMaternal morbidityObstetric outcomesCohort studyFetal distressBlood lossBlood pressureIndependent predictorsVentricular dysrhythmiasAnesthetic implicationsEpidural anesthesiaIschemic episodesPregnant womenPrenatal careUnivariate analysisParturients
1995
Thrombocytopenia in pregnant women who use cocaine
Kain Z, Mayes L, Pakes J, Rosenbaum S, Schottenfeld R. Thrombocytopenia in pregnant women who use cocaine. American Journal Of Obstetrics And Gynecology 1995, 173: 885-890. PMID: 7573263, DOI: 10.1016/0002-9378(95)90360-7.Peer-Reviewed Original ResearchConceptsLow platelet countDrug-free groupPlatelet countCocaine groupHuman immunodeficiency virus statusCocaine-abusing parturientsRate of thrombocytopeniaIndependent risk factorAssociation of thrombocytopeniaCocaine-using groupIllicit drug useParturient populationSeropositive womenCohort studyPregnant womenDrug groupsPrenatal centersMedical recordsRisk factorsVirus statusMedical conditionsThrombocytopeniaIllicit drug usageNineteen subjectsOpiate group
1993
Cocaine Abuse in the Parturient and Effects on the Fetus and Neonate.
Kain Z, Rimar S, Barash P. Cocaine Abuse in the Parturient and Effects on the Fetus and Neonate. Anesthesia & Analgesia 1993, 77: 835. PMID: 8214673, DOI: 10.1213/00000539-199310000-00030.Peer-Reviewed Original ResearchConceptsCocaine abuseIntraoperative anesthetic managementUse of cocainePrecipitate deliveryPlacental abruptionPreterm laborAnesthetic managementOrgan involvementPremature ruptureSyphilis serologyPregnant womenPrenatal careHematologic systemIndependent contributorsCocaine useAlcohol useIllicit drugsParturientsNeonatesFetusesImportant predictorCocaineWomenAbuseAbruption
1992
Effect of Cocaine Use on the Fetus
Kain Z, Kain T, Scarpelli E. Effect of Cocaine Use on the Fetus. New England Journal Of Medicine 1992, 327: 1393-1394. PMID: 1406850, DOI: 10.1056/nejm199211053271917.Peer-Reviewed Original ResearchCocaine Exposure in utero: Perinatal Development and Neonatal Manifestations - Review
Kain Z, Kain T, Scarpelli E. Cocaine Exposure in utero: Perinatal Development and Neonatal Manifestations - Review. Journal Of Toxicology Clinical Toxicology 1992, 30: 607-636. PMID: 1433431, DOI: 10.3109/15563659209017946.Peer-Reviewed Original ResearchConceptsCocaine exposureTeratogenic effectsProspective human studiesMonths of pregnancyIllicit drugsMost animal studiesMajor structural malformationsPrenatal careHuman studiesAnimal studiesStructural malformationsFetal developmentPerinatal developmentCocaine useLittle specific informationHuman dataPregnancyUteroExposureDrugsAbnormalitiesMalformationsCareCocaineMonths
1991
Enhanced Lung Maturation in Cocaine-Exposed Rabbit Fetuses
Kain Z, Chinoy M, Antonio-Santiago M, Marchitelli R, Scarpelli E. Enhanced Lung Maturation in Cocaine-Exposed Rabbit Fetuses. Pediatric Research 1991, 29: 534-537. PMID: 1866207, DOI: 10.1203/00006450-199106010-00003.Peer-Reviewed Original ResearchConceptsLung weightLung maturationAccelerated lung maturationDry lung weightRespiratory distress syndromeWet lung weightSerum cortisol levelsFetal amniotic fluidFetal rabbit lungCocaine-exposed fetusesCocaine-addicted mothersInitial lungDistress syndromeFetal exposureMaternal exposureD gestationLung distensibilityPregnant damsCortisol surgeBody weightAmniotic fluidCortisol levelsRabbit fetusesRabbit lungsSeptal wall