2011
Cardiac output and not blood pressure correlates with cerebral oxygenation after phenylephrine and ephedrine treatment of anesthesia-induced hypotension
Meng L, Alexander B, Rinehart J, Kain Z, Mantulin W, Cannesson M. Cardiac output and not blood pressure correlates with cerebral oxygenation after phenylephrine and ephedrine treatment of anesthesia-induced hypotension. European Journal Of Anaesthesiology 2011, 28: 66-67. DOI: 10.1097/00003643-201106001-00209.Peer-Reviewed Original ResearchCommentaries on ‘Non‐pharmacological interventions for assisting the induction of anaesthesia in children’ with a response by the review authors
Kain Z, Strom S, Kim J, Splinter W, Cyna A. Commentaries on ‘Non‐pharmacological interventions for assisting the induction of anaesthesia in children’ with a response by the review authors. Evidence-Based Child Health A Cochrane Review Journal 2011, 6: 137-140. DOI: 10.1002/ebch.671.Peer-Reviewed Original Research
2001
Premedication and parental presence revisited
Kain Z. Premedication and parental presence revisited. Current Opinion In Anaesthesiology 2001, 14: 331. PMID: 17019112, DOI: 10.1097/00001503-200106000-00009.Peer-Reviewed Original ResearchSensory Stimuli and Anxiety in Children Undergoing Surgery: A Randomized, Controlled Trial
Kain Z, Wang S, Mayes L, Krivutza D, Teague B. Sensory Stimuli and Anxiety in Children Undergoing Surgery: A Randomized, Controlled Trial. Anesthesia & Analgesia 2001, 92: 897-903. PMID: 11273921, DOI: 10.1097/00000539-200104000-00018.Peer-Reviewed Original ResearchConceptsInduction of anesthesiaChildren Undergoing SurgeryPostoperative day 1Postoperative behavioral changesSensory stimuliPost Hospitalization Behavior QuestionnaireUndergoing surgeryBehavioral recoveryIncreased complianceStimulation groupDay 1AnesthesiaControl groupAnesthesia maskOperating room lightsSurgeryAnxiety of childrenBehavioral interventionsOperating roomChildrenBehavioral changesExhibit low levelsBehavior QuestionnaireInductionAnxiety
2000
Midazolam: Effects on Amnesia and Anxiety in Children
Kain Z, Hofstadter M, Mayes L, Krivutza D, Alexander G, Wang S, Reznick J. Midazolam: Effects on Amnesia and Anxiety in Children. Anesthesiology 2000, 93: 676. PMID: 10969300, DOI: 10.1097/00000542-200009000-00016.Peer-Reviewed Original ResearchConceptsOral midazolamMidazolam administrationAnterograde amnesiaGood anterograde amnesiaSignificant anterograde amnesiaInduction of anesthesiaSignificant anxiolytic effectMidazolam groupGeneral anesthesiaSignificant group differencesAnxiolytic effectsBusy operating roomSurgical proceduresPostintervention testingDrug AdministrationControl groupMidazolamBaseline testingAnxiety measurement toolAnxiety of childrenOperating roomAdministrationGroup differencesPicture cardsAnesthesia
1999
Preoperative Anxiety and Intraoperative Anesthetic Requirements
Maranets I, Kain Z. Preoperative Anxiety and Intraoperative Anesthetic Requirements. Anesthesia & Analgesia 1999, 89: 1346. DOI: 10.1213/00000539-199912000-00003.Peer-Reviewed Original ResearchConceptsIntraoperative anesthetic requirementsMaintenance of anesthesiaAnesthetic requirementsPropofol dosesPreoperative anxietyBaseline anxietyHypnotic componentAnesthetic stateIntraoperative propofol requirementsLaparoscopic tubal ligationCross-sectional studyHigh baseline anxietyAnxiety levelsBispectral index monitorMore propofolAnesthetic regimenIndependent predictorsPropofol requirementsInitial doseTubal ligationLarge dosesPatientsState anxietyAnxious patientsAnesthesiaAn alternative method to alleviate postoperative nausea and vomiting in children
Wang S, Hofstadter M, Kain Z. An alternative method to alleviate postoperative nausea and vomiting in children. Journal Of Clinical Anesthesia 1999, 11: 231-234. PMID: 10434220, DOI: 10.1016/s0952-8180(99)00035-5.Peer-Reviewed Original ResearchConceptsPostoperative nauseaGeneral anesthesiaTreatment groupsControl groupASA physical status IPediatric surgery centersPhysical status IElective outpatient surgeryVisual analog scaleChildren ages 6Intravenous ondansetronAntiemetic effectRescue therapyStatus IRecurrent nauseaAnalog scaleOutpatient surgerySurgery centersNauseaVomitingEffective treatmentTreatment sequenceAge 6SurgeryAnesthesia
1998
Parental Presence during Induction of Anesthesia versus Sedative Premedication
Kain Z, Mayes L, Wang S, Caramico L, Hofstadter M. Parental Presence during Induction of Anesthesia versus Sedative Premedication. Anesthesiology 1998, 89: 1147-1156. PMID: 9822003, DOI: 10.1097/00000542-199811000-00015.Peer-Reviewed Original ResearchConceptsInduction of anesthesiaMidazolam groupControl groupParental presenceOral midazolamEnd pointParental presence groupPrimary end pointSecondary end pointsParental anxiety scoresPerioperative periodPreoperative periodPreoperative anxietySedative premedicationAnesthesia maskAnesthesiaMidazolamOperating roomAnxiety scoresParent anxietyChildrenLess anxietyInterventionAnxietyInduction
1996
Parental Presence during Induction of Anesthesia
Kain Z, Mayes L, Caramico L, Silver D, Spieker M, Nygren M, Anderson G, Rimar S. Parental Presence during Induction of Anesthesia. Anesthesiology 1996, 84: 1060-1067. PMID: 8623999, DOI: 10.1097/00000542-199605000-00007.Peer-Reviewed Original ResearchConceptsInduction of anesthesiaSerum cortisol concentrationsLow baseline levelsParental presencePhysiologic measuresBaseline levelsCortisol concentrationsPreoperative behavioral interventionsMultivariate linear regression analysisOutpatient surgeryIntervention groupLinear regression analysisControl groupParent-absent groupBaseline temperamentAnesthesiaBehavioral interventionsChild's ageSignificant differencesChildrenRegression analysisInterventionLow trait anxietyTrait anxietyAnxiety
1994
Physiology and management of cocaine exposure preceding emergency anesthesia and surgery.
Kain Z, Rosenbaum S. Physiology and management of cocaine exposure preceding emergency anesthesia and surgery. Current Opinion In Anaesthesiology 1994, 7: 293. DOI: 10.1097/00001503-199406000-00016.Peer-Reviewed Original ResearchManagement of tracheobronchial and esophageal foreign bodies in children: A survey study
Kain Z, O'Connor T, Berde C. Management of tracheobronchial and esophageal foreign bodies in children: A survey study. Journal Of Clinical Anesthesia 1994, 6: 28-32. PMID: 8142095, DOI: 10.1016/0952-8180(94)90114-7.Peer-Reviewed Original ResearchConceptsForeign bodyInhalation inductionGastroesophageal tractPediatric anesthesiaAnatomic locationMultiple logistic regression analysisRapid sequence inductionInduction of anesthesiaForeign body locationEsophageal foreign bodiesChoice of drugCurrent anesthetic managementChoice of inductionAnesthetic managementCricoid pressureIntravenous inductionMask inductionSupraglottic areaTracheobronchial treeClinical scenariosMost anatomic locationsAnesthesia experienceAnesthesiaPractice typeSafety pin