2017
Quantitative Limits on Small Molecule Transport via the Electropermeome — Measuring and Modeling Single Nanosecond Perturbations
Sözer EB, Levine ZA, Vernier PT. Quantitative Limits on Small Molecule Transport via the Electropermeome — Measuring and Modeling Single Nanosecond Perturbations. Scientific Reports 2017, 7: 57. PMID: 28246401, PMCID: PMC5428338, DOI: 10.1038/s41598-017-00092-0.Peer-Reviewed Original Research
2015
Picosecond and Terahertz Perturbation of Interfacial Water and Electropermeabilization of Biological Membranes
Vernier PT, Levine ZA, Ho MC, Xiao S, Semenov I, Pakhomov AG. Picosecond and Terahertz Perturbation of Interfacial Water and Electropermeabilization of Biological Membranes. The Journal Of Membrane Biology 2015, 248: 837-847. PMID: 25796485, PMCID: PMC4565733, DOI: 10.1007/s00232-015-9788-7.Peer-Reviewed Original ResearchConceptsSubnanosecond Electric PulsesTerahertz electromagnetic radiationComplementary molecular dynamics simulationsTerahertz frequenciesElectromagnetic radiationField reversalElectric pulsesElectric fieldInterfacial waterElectropore formationMolecular dynamics simulationsPulsesElectric potentialConductive structuresWater dipolesDynamics simulationsPhospholipid bilayersBilayersPicosecondsRemote monitoringBiological membranesModel membranesFieldPSRadiation
2009
Electroporating Fields Target Oxidatively Damaged Areas in the Cell Membrane
Vernier PT, Levine ZA, Wu YH, Joubert V, Ziegler MJ, Mir LM, Tieleman DP. Electroporating Fields Target Oxidatively Damaged Areas in the Cell Membrane. PLOS ONE 2009, 4: e7966. PMID: 19956595, PMCID: PMC2779261, DOI: 10.1371/journal.pone.0007966.Peer-Reviewed Original ResearchConceptsLiving cellsComplex biomolecular assembliesPlasma membraneMolecular basisGenetic materialMembrane componentsCell membraneBiomolecular assembliesPermeabilization procedureModel membranesElectroporation protocolReversible electropermeabilizationOxidative stressElectropermeabilizationMembraneCell suspensionsDetailed understandingMolecular dynamics simulationsGene therapyCellsConsiderable knowledgeAssemblyDynamics simulationsPharmaceutical agents